Search results for "CTL"

Melanoma-Reactive Class I-Restricted Cytotoxic T Cell Clones Are Stimulated by Dendritic Cells Loaded with Synthetic Peptides, but Fail to Respond to…

2003

Abstract Immunization with heat shock proteins (hsp) isolated from cancer cells has been shown to induce a protective antitumor response. The mechanism of hsp-dependent cellular immunity has been attributed to a variety of immunological activities mediated by hsp. Hsp have been shown to bind antigenic peptides, trim the bound peptides by intrinsic enzymatic activity, improve endocytosis of the chaperoned peptides by APCs, and enhance the ability of APCs to stimulate peptide-specific T cells. We have investigated the potential capacity of hsp70 and gp96 to function as a mediator for Ag-specific CTL stimulation in an in vitro model for human melanoma. Repetitive stimulation of PBLs by autolog…

The adiabatic strictly-correlated-electrons functional : kernel and exact properties

2016

We investigate a number of formal properties of the adiabatic strictly-correlated electrons (SCE) functional, relevant for time-dependent potentials and for kernels in linear response time-dependent density functional theory. Among the former, we focus on the compliance to constraints of exact many-body theories, such as the generalised translational invariance and the zero-force theorem. Within the latter, we derive an analytical expression for the adiabatic SCE Hartree exchange-correlation kernel in one dimensional systems, and we compute it numerically for a variety of model densities. We analyse the non-local features of this kernel, particularly the ones that are relevant in tackling p…

Painlevé analysis and exact solutions for the coupled Burgers system

2006

We perform the Painleve test to a system of two coupled Burgers-type equations which fails to satisfy the Painleve test. In order to obtain a class of solutions, we use a slightly modified version of the test. These solutions are expressed in terms of the Airy functions. We also give the travelling wave solutions, expressed in terms of the trigonometric and hyperbolic functions.

On deformation of Poisson manifolds of hydrodynamic type

2001

We study a class of deformations of infinite-dimensional Poisson manifolds of hydrodynamic type which are of interest in the theory of Frobenius manifolds. We prove two results. First, we show that the second cohomology group of these manifolds, in the Poisson-Lichnerowicz cohomology, is ``essentially'' trivial. Then, we prove a conjecture of B. Dubrovin about the triviality of homogeneous formal deformations of the above manifolds.

Positivity, complex FIOs, and Toeplitz operators

2018

International audience; We establish a characterization of complex linear canonical transformations that are positive with respect to a pair of strictly plurisubharmonic quadratic weights. As an application, we show that the boundedness of a class of Toeplitz operators on the Bargmann space is implied by the boundedness of their Weyl symbols.

Integrable systems, Frobenius manifolds and cohomological field theories

2022

In this dissertation, we study the underlying geometry of integrable systems, in particular tausymmetric bi-Hamiltonian hierarchies of evolutionary PDEs and differential-difference equations.First, we explore the close connection between the realms of integrable systems and algebraic geometry by giving a new proof of the Witten conjecture, which constructs the string taufunction of the Korteweg-de Vries hierarchy via intersection theory of the moduli spaces of stable curves with marked points. This novel proof is based on the geometry of double ramification cycles, tautological classes whose behavior under pullbacks of the forgetful and gluing maps facilitate the computation of intersection…

Subdirectly irreducible generalized sums of upper semilattice ordered systems of algebras

2002

In [15] the generalized sum of an upper (F 1 , F 2 )-semilattice ordered system of algebras was defined. In this paper we find necessary and sufficient conditions under which this construction yields subdirectly irreducible algebras.

Normed vector spaces consisting of classes of convex sets

1965

Spectral approach to the scattering map for the semi-classical defocusing Davey–Stewartson II equation

2019

International audience; The inverse scattering approach for the defocusing Davey–Stewartson II equation is given by a system of D-bar equations. We present a numerical approach to semi-classical D-bar problems for real analytic rapidly decreasing potentials. We treat the D-bar problem as a complex linear second order integral equation which is solved with discrete Fourier transforms complemented by a regularization of the singular parts by explicit analytic computation. The resulting algebraic equation is solved either by fixed point iterations or GMRES. Several examples for small values of the semi-classical parameter in the system are discussed.

Rational solutions to the KPI equation from particular polynomials

2022

Abstract We construct solutions to the Kadomtsev–Petviashvili equation (KPI) from particular polynomials. We obtain rational solutions written as a second spatial derivative of a logarithm of a determinant of order n . We obtain with this method an infinite hierarchy of rational solutions to the KPI equation. We give explicitly the expressions of these solutions for the first five orders.