Search results for "Cain"
showing 10 items of 410 documents
D-TMS IN COCAINE ADDICTION: preliminary findings
2015
Cocaine-related disorders are currently among the most devastating mental disease as they leads to profound disturbances in an individual’s behaviour resulting in tremendous economic, social, and moral costs. Imaging studies in human have shown a reduction of dopamine (DA) receptors accompanied by a lesser release of endogenous DA in the ventral striatum (AVT) of cocaine subjects thereby resulting in a ‘dopamine-impoverished’ brain[1-2]. This perturbations lead to neuroadpatations in several other circuits which are related to motivation, inhibitory control, and memory which finally determ compulsive-impulsive self drug administration[3]. The lasting reduction in physiological activity of t…
Effects of Propofol (Intravenous Propofol Emulsion) on Cell Membranes Measured by Electrofusion and Electroporation
2011
The influence of propofol (CAS 2078-54-8 (intravenous propofol emulsion) on cell membrane properties was investigated in vitro with techniques of cell electrofusion and cell electroporation. Human lymphoma cells and plant protoplasts were chosen as a model system. Propofol (intravenous propofol emulsion) decreased the electrofusion yield of the cells and their membrane permeability. A 50% decrease in relative electrofusion was observed in human lymphoma cells in the presence of about 0.05 mmol/l propofol (intravenous propofol emulsion) and in plant protoplasts in the presence of about 0.1 mmol/l. The fusion of human lymphoma cells was inhibited to 100% at concentrations higher than 0.2 mmol…
Comparing illicit drug use in 19 European cities through sewage analysis
2012
Abstract: The analysis of sewage for urinary biomarkers of illicit drugs is a promising and complementary approach for estimating the use of these substances in the general population. For the first time, this approach was simultaneously applied in 19 European cities, making it possible to directly compare illicit drug loads in Europe over a 1-week period. An inter-laboratory comparison study was performed to evaluate the analytical performance of the participating laboratories. Raw 24-hour composite sewage samples were collected from 19 European cities during a single week in March 2011 and analyzed for the urinary biomarkers of cocaine, amphetamine, ecstasy, methamphetamine and cannabis u…
Masculinité transnationale et corps-mâle dans les romans d’Abdellah Taïa
2016
I romanzi dello scrittore marocchino d'espressione francese Abdellah Taïa esaminano con attenzione la maschilità nel contesto migratorio. Omosessuale ed esiliato, Taïa cerca di costruire la sua identità sessuale secondo il modello occidentale; così facendo, contribuisce alla creazione di una maschilità islamica transnazionale che si decentra, pur restando ancorata all'eredità culturale delle sue terre d'origine. L'articolo si propone di interrogare le modalità di tale costruzione identitaria a partire dagli studi di Connell sulla maschilità egemonica e dalla psicoanalisi lacaniana applicata alla dimensione immaginaria del corpo. The novels of the French Moroccan writer Abdellah Taïa examine…
Meanings of travel in the musical discourse of blues: Roosevelt “Grey Ghost” Williams and “Lonesome Traveller”
2016
El objetivo de este artículo es investigar, desde una perspectiva comunicativa, socio-semiótica y etnomusicológica, la construcción de sentido sobre el viaje y el estilo de vida itinerante (hobo) en el discurso musical del blues. Primero realizaremos una contextualización histórica del viaje en la tradición afroamericana, y después analizaremos el caso del legendario músico texano Roosevelt «Grey Ghost» Williams (1903-1996) y de su composición «Lonesome Traveller» («viajero solitario»), en la que se representa el sujeto y estilo de vida hobo (trabajador migrante y sin hogar). En ese proceso, discutiremos el sentido del viaje como imposición y el sentido del viaje como signo de independencia…
Influence of social stress on the rewarding effects of cocaine
2016
Les relacions socials són un procés crucial en el desenvolupament de l’ésser humà, i en altres espècies socials que viuen en jerarquies socials complexes. L’entorn i l’ambient en el qual es desenvolupa un individu és fonamental, ja que tindrà un gran impacte sobre el seu benestar, el manteniment de la salut i la seua supervivència (Kessler i cols., 2010). La resposta a l'estrés és un factor clau en el manteniment de l'homeòstasi i la salut de l'individu. Aquesta dependrà de la interacció amb l’entorn i l’activitat de certs sistemes regulatoris de l’organisme, com són el sistema nerviós simpàtic i l’eix hipotàlem-hipofisari-adrenal (HPA) (Stratakis i Chrousos, 1995). Diferents tipus d'estrés…
Avant-garde, genre et industrie à l’épreuve de l’auteur. Les films mexicains de Buñuel
2012
Ce cours n’étant pas axé sur l’histoire du cinéma, il ne sera pas question d’approfondir sur l’industrie, la législation, les activités des scénaristes ni des techniciens au sein du cinéma mexicain. Il s’agira plutôt d’analyser une série de films mexicains de Buñuel en vue d’éclairer l’esthétique du cinéma, notamment le style, le genre et la fonction de l’auteur.
Inflammation as a pathway between social stress and enhanced sensitivity to cocaine
2019
La respuesta al estrés es una estrategia adaptativa que nos ayuda a movilizar recursos para enfrentarnos a situaciones que ponen en riesgo nuestra supervivencia (Ulrich-Lai y Herman, 2009). Sin embargo, en nuestra sociedad el estrés constante se ha convertido en un problema relevante. Vivimos en un entorno social complejo que nos obliga a enfrentamos persistentemente a estresores “cotidianos” (Pearlin y Skaff, 1995) como por ejemplo los problemas de conciliación entre la vida laboral y familiar, discusiones de pareja y problemas económicos (Almeida, 2005), que puede llegar a afectar a nuestro bienestar incluso más que eventos más intensos pero menos frecuentes (Serido y cols., 2004). Esta e…
Valutazione di un rolling group ambulatoriale per pazienti con diagnosi di abuso da cocaina
2014
Lo studio utilizza un disegno longitudinale a misure ripetute per la valutazione process-outcome di un rolling groups psicodinamico per pazienti con diagnosi di abuso di cocaina. La terapia condotta su 18 pazienti è stata effettuata all’interno del Centro Clinico Cocainomani dell’ASP di Brescia. Gli strumenti utilizzati sono: DAST-20, OQ-45, DSQ, CALPAS Group, GMLCS. Le analisi condotte attraverso il Multilevel Models evidenziano dei miglioramenti attendibili sia rispetto al sintomo che riguardo al funzionamento psicologico e all’assetto difensivo. La lunghezza della partecipazione alla terapia e la stabilità del gruppo influenzano l’esito. I pazienti che restano di più in trattamento speri…
Quadratus Lumborum Block Reduces Postoperative Opioid Consumption and Decreases Persistent Postoperative Pain Severity in Patients Undergoing Both Op…
2021
Background: New regional techniques can improve pain management after nephrectomy. Methods: This study was a randomized controlled trial conducted at two teaching hospitals. Patients undergoing elective open and laparoscopic nephrectomy were eligible to participate in the trial. A total of 100 patients were divided into a quadratus lumborum block (QLB) group (50 patients) and a control (CON) group (50 patients). At the end of surgery, but while still under general anesthesia, unilateral QLB with ropivacaine was performed on the side of nephrectomy for patients in the QLB group. The main measured outcome of this study was oxycodone consumption via a patient-controlled anesthesia (PCA) pump d…