Search results for "Canada"
showing 10 items of 103 documents
Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC st…
2006
Abstract Objective Estimate the prevalence of urinary incontinence (UI), overactive bladder (OAB), and other lower urinary tract symptoms (LUTS) among men and women in five countries using the 2002 International Continence Society (ICS) definitions. Methods This population-based, cross-sectional survey was conducted between April and December 2005 in Canada, Germany, Italy, Sweden, and the United Kingdom using computer-assisted telephone interviews. A random sample of men and women aged ≥ 18 yr residing in the five countries and who were representative of the general populations in these countries was selected. Using 2002 ICS definitions, the prevalence estimates of storage, voiding, and po…
Results of the Thyroid Cancer Alliance international patient/survivor survey: Psychosocial/informational support needs, treatment side effects and in…
2013
To comprehensively assess the experience of a large, diverse cohort and identify potential care improvements, the Thyroid Cancer Alliance, an international patient/survivor group coalition, surveyed thyroid cancer patients/survivors worldwide.English, German, French or Spanish versions of a self-developed 43-item questionnaire were completed, predominantly online, by 2398 respondents from the US (37.9%), Germany (21.3%), the UK (11.5%), Canada (11.4%), France (9%), and 35 other countries. Females and differentiated thyroid carcinoma patients each comprised ~87% of respondents. Diagnosis occurred at age 30-59 years in 71.8%, within1 (1-5) year(s) before survey completion in 16.4% (55%).At di…
Safety and efficacy of alirocumab in a real-life setting: the ODYSSEY APPRISE study
2020
Abstract Aims To obtain safety and efficacy data of alirocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in a real-life setting in high cardiovascular (CV) risk patients with heterozygous familial hypercholesterolaemia (HeFH) or very-high low-density lipoprotein cholesterol (LDL-C) levels despite maximally tolerated dose of statin ± other lipid-lowering therapies (MTD ± LLTs). ODYSSEY APPRISE was a prospective, single-arm, Phase 3b open-label (≥12 weeks to ≤ 30 months) European/Canadian study with alirocumab. Methods and results Patients received alirocumab 75 or 150 mg every 2 weeks, with dose adjustment based on physician’s judgment. In total, 994 patients were enrolled …
A CASCADE of effects of bisphenol A
2009
International audience
Global treatment patterns and outcomes among patients with recurrent and/or metastatic head and neck squamous cell carcinoma: Results of the GLANCE H…
2020
Abstract Objectives Given a lack of universally-accepted standard-of-care treatment for patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC), study objectives were to assess treatment utilization and survival outcomes for R/M HNSCC in the real-world setting. Materials and methods A multi-site retrospective chart review was conducted in Europe (Germany, United Kingdom, Italy, Spain), Asia Pacific (Australia, South Korea, Taiwan), and Latin/North America (Brazil and Canada) to identify patients who initiated first-line systemic therapy for R/M HNSCC between January 2011 and December 2013. Patients were followed through December 2015 to collect clinical characte…
CEO’s Letter Accompanying the Report on Corporate social Responsibility of Canadian Listed Firms: An Analysis of the Content and the Links with Some …
2016
International audience; The disclosure of Corporate Social Responsibility (CSR) by Canadian firms is not mandatory. This provides an ideal context to describe the nature of what is being freely disclosed by large firms and to study the firms’ characteristics which lead to such disclosure. We searched all TSX listed firms to find those which disclose a CSR report accompanied by a letter from the CEO. In the end, we study 89 CEO’s letters; that is, all the firms disclosing both a CSR report and a CEO’s letter. We first looked at the nature of the elements disclosed. We classified them in 3 categories: (1) actual accomplishments in the field of CSR, (2) values and (3) future objectives. The «a…
Oxygen isotope composition of North American bobcat (Lynx rufus) and puma (Puma concolor) bone phosphate: implications for provenance and climate rec…
2015
Feline carnivores are threatened by illegal wildlife trade. Tracing the provenance of unknown felid tissues via stable isotope analysis could provide important information in wildlife crime investigations. The oxygen isotope composition of mammalian skeletal phosphate (δ(18)Op) is widely applied to trace the origin of animal remains and to reconstruct migratory patterns in palaeontological, archaeological, ecological and wildlife forensic applications. Teeth and bones of terrestrial mammals form at constant body temperature in isotope equilibrium with body water, which is predominantly controlled by ingested meteoric water (δ(18)Ow) that varies systematically with latitude, altitude and cli…
Par emigrācijas (no Liepājas uz Kanādu) demogrāfisko ietekmi laika posmā no 1906. līdz 1914. gadam
2021
Darbā tiek apskatīta emigrācijas plūsma no Krievijas Impērijas uz Kanādu caur Libau (mūsdienās – Liepāju) ostu laika posmā no 1906. – 1914. gadam, kad starp Libau un Ziemeļameriku bija tieša jūras ceļu satiksme. Pētījuma pamatā ir oriģinālie kuģniecības manifesti, kas tiek salīdzināti un pretstatīti akadēmiskajiem pētījumiem par dažādām emigrantu grupām Kanādā. Pieejamie dati par galvenajām etniskajām grupām astoņu gadu posmā tiek salīdzināti, pretstatīti un papildināti ar aptaujāto emigrantu, kas emigrējuši no Krievijas Impērijas uz Kanādu šajā laika posmā, pēcteču teikto un Libau ostas apstākļu analīzi šīs emigrācijas laikā, kas balstīta šī laika krievu, britu, amerikāņu, ebreju un latvie…
Flow cytometry diagnosis in myelodysplastic syndrome: Current practice in Latin America and comparison with other regions of the world
2019
Background: Flow cytometry (FC) is a valuable tool for the diagnosis of myelodysplastic syndromes (MDS). We present results of a survey carried out to evaluate FC current practice for MDS diagnosis in Latin America (LA), focusing on markers used and characteristics of the clinical diagnostic report. Compliance to IMDSflow recommendations was also evaluated. These practices were then compared with those used in other countries. Methods: An online survey was sent through the Grupo Latino-Americano de Mielodisplasia to LA cytometrists and other international scientific societies. Results: 91 responses from 15 LA countries were received. The median of the number of markers used was 20 +/- 4.5, …
Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells
2015
Abstract Ethnopharmacological relevance Traditional medicine of the Native Americans has a long tradition of medicinal plants, which also influenced modern oncology. For instance, podophyllotoxin the active ingredient of Podophyllum peltatum L. (Berberidaceae) used by Native Americans to treat warts led to the development of etoposide and teniposide. In the present investigation, we studied 10 medicinal plants used by the Gwich׳in First Nation of West-Canada, which have been used against diverse diseases including cancer. Material and methods Sensitive and multidrug-resistant (MDR) tumor cell lines expressing various ATP-binding cassette (ABC) transporters (P-glycoprotein/ ABCB1/MDR1 , MRP1…