Search results for "Canth"

showing 10 items of 262 documents

Molecular modes of action of cantharidin in tumor cells

2005

Cancer chemotherapy is often limited by patient's toxicity and tumor drug resistance indicating that new drug development and modification of existing drugs is critical for improving the therapeutic response. Traditional Chinese medicine is a rich source of potential anticancer agents. In particular, cantharidin (CAN), the active principle ingredient from the blister beetle, Mylabris, has anti-tumor activity, but the cytotoxic mechanism is unknown. In leukemia cells, cantharidin induces apoptosis by a p53-dependent mechanism. Cantharidin causes both DNA single- and double-strand breaks. Colony-forming assays with knockout and transfectant cells lines showed that DNA polymerase beta, but not…

DNA RepairDNA damageDNA repairBlister beetleAntineoplastic AgentsApoptosisDNA polymerase betaBiologyBiochemistrychemistry.chemical_compoundCell Line TumorHumansPharmacologyGeneticsCantharidinBase excision repairEndonucleasesbiology.organism_classificationDNA-Binding ProteinsOxidative StresschemistryCantharidinCancer researchERCC1DNA DamageNucleotide excision repairBiochemical Pharmacology
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Traditionally used Thai medicinal plants: in vitro anti-inflammatory, anticancer and antioxidant activities.

2009

In order to assess traditional Thai claims about the therapeutic potential of medicinal plants and to select plants for future phytochemical research, nine plant species with anti-inflammatory uses were selected from Thai textbooks and assessed for their in vitro anti-inflammatory, antiproliferative and antioxidant activities.Nuclear factor-kappaB (NF-kappaB) inhibitory effects in stably transfected HeLa cells were determined by luciferase assay, and effects on LPS-induced pro-inflammatory mediators prostaglandin E2 (PGE2), interleukin (IL)-6, IL-1beta, and tumour necrosis factor (TNF)alpha in primary monocytes were assessed by ELISA. Cytotoxic activities were examined against HeLa cells, h…

DPPHmedicine.drug_classCell SurvivalInterleukin-1betaAnti-Inflammatory AgentsPharmacognosyAsteraceaeTransfectionAnti-inflammatoryAntioxidantsDinoprostoneMonocytesHeLachemistry.chemical_compoundInhibitory Concentration 50MagnoliopsidaPhenolsDrug DiscoveryMedicineHumansGynuraPharmacologyPlants MedicinalTraditional medicinebiologyDose-Response Relationship Drugbusiness.industryInterleukin-6Plant ExtractsTumor Necrosis Factor-alphaNF-kappa Bbiology.organism_classificationThailandOroxylum indicumAntineoplastic Agents PhytogenicPolygonaceaeRhinacanthus nasutusPhytochemicalchemistryDrug Resistance NeoplasmBignoniaceaeLipid PeroxidationMedicine TraditionalInflammation MediatorsbusinessHeLa CellsJournal of ethnopharmacology
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Intestinal helminth communities of the long-finned pilot whale (Globicephala melas) off the Faroe Islands.

1993

SUMMARYThe intestines of 170 long-finned pilot whales, Globicephala melas, caught off the Faroe Islands (N.E. Atlantic) were examined for helminth parasites. Eight species were detected but only 4 occurred in at least 10% of the sample. No core or recurrent group of species were identified and no correlations between abundances of species were significant. Diversity values were far below those reported for other endotherms. Colonization by helminths was random, whales not being readily colonized. These features point to largely unpredictable, isolationist infracommunities, there being little potential for inter-specific interactions. Older hosts tended to harbour more diverse infracommuniti…

DenmarkCetaceaPilot whaleAcanthocephalaHelminthsparasitic diseasesHelminthsAnimalsAtlantic OceanbiologyCommunityEcologyEcologyMarine habitatsWhalesSpecies diversitybiology.organism_classificationGlobicephala melasBiological EvolutionIntestinesInfectious DiseasesCestodaAnimal Science and ZoologyParasitologySpecies richnessTrematodaParasitology
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Sexual segregation of Echinorhynchus borealis von Linstow, 1901 (Acanthocephala) in the gut of burbot (Lota lota Linnaeus)

2015

Helminths often occupy defined niches in the gut of their definitive hosts. In the dioecious acanthocephalans, adult males and females usually have similar gut distributions, but sexual site segregation has been reported in at least some species. We studied the intestinal distribution of the acanthocephalan Echinorhynchus borealis von Linstow, 1901 (syn. of E. cinctulus Porta, 1905) in its definitive host, burbot (Lota lota Linnaeus). Over 80% of female worms were found in the pyloric caeca, whereas the majority of males were in the anterior two-thirds of the intestine. This difference was relatively consistent between individual fish hosts. Worms from different parts of the gut did not dif…

Ecological nichebiologyspatial distributionEcologyNichemicrohabitatZoologyAquatic animalEchinorhynchus cinctulussex ratiobiology.organism_classificationthorny-headed wormsnicheEchinorhynchidaeParasite hostingHelminthsta1181ParasitologyMatingAcanthocephalabody sizeSex ratioFolia Parasitologica
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Coincidental loss of bacterial virulence in multi-enemy microbial communities.

2014

The coincidental virulence evolution hypothesis suggests that outside-host selection, such as predation, parasitism and resource competition can indirectly affect the virulence of environmentally-growing bacterial pathogens. While there are some examples of coincidental environmental selection for virulence, it is also possible that the resource acquisition and enemy defence is selecting against it. To test these ideas we conducted an evolutionary experiment by exposing the opportunistic pathogen bacterium Serratia marcescens to the particle-feeding ciliate Tetrahymena thermophila, the surfacefeeding amoeba Acanthamoeba castellanii, and the lytic bacteriophage Semad11, in all possible combi…

Ecological selectionBacteriophageNatural SelectionBacteriophagesANTAGONISTIC COEVOLUTIONLISTERIA-MONOCYTOGENESSerratia marcescens1183 Plant biology microbiology virologyGeneticsSERRATIA-MARCESCENSAcanthamoeba castellanii0303 health sciencesMultidisciplinaryEcologybiologyQTetrahymenaRAcanthamoeba castellaniiMedicineResearch ArticleEvolutionary ProcessesVirulence FactorsAntagonistic CoevolutionScienceMicrobial ConsortiaeducationVirulenceMicrobiologyMicrobial EcologyMicrobiologyEvolution Molecular03 medical and health sciencesmulti-enemy microbial communitiesWater environment030304 developmental biologySTAPHYLOCOCCUS-AUREUSEvolutionary BiologyPSEUDOMONAS-AERUGINOSA VIRULENCE030306 microbiologybacterial virulenceDICTYOSTELIUM-DISCOIDEUMBiology and Life SciencesBacteriologybiology.organism_classificationOrganismal EvolutionArtificial SelectionTETRAHYMENA-THERMOPHILAEvolutionary EcologyMicrobial Evolutionta1181AMEBA ACANTHAMOEBA-CASTELLANIILEGIONELLA-PNEUMOPHILABacteriaMEDIA COMPOSITION INFLUENCESPLoS ONE
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Acanthocephala in fish from the Bothnian Bay, Finland

1990

A sample of 7266 fish from 31 species was obtained from the north-eastern Bothnian Bay, Baltic Sea, from 1975 to 1982. Twenty-six fish species were found to be infected with seven acanthocephalan species identified as Echinorhynchus salmonis, E. bothniensis, E. borealis, E. gadi, Acanthocephalus anguillae, A. lucii and Neoechinorhynchus rutili. Acanthocephalus lucii was the only acanthocephalan not to attain sexual maturity M at least one species of fish. Fourteen new host records were found for E. bothniensis. A total of 1576 acanthocephalan infections was found; in most cases these were single species infections, but in 108 cases infections of two, and in two cases of three species were o…

EcologyRange (biology)Acanthocephalus anguillaeHelminthsGadusAnimal Science and ZoologyAquatic animalBiologybiology.organism_classificationAcanthocephalaEcology Evolution Behavior and SystematicsLeuciscus idusCoregonus widegreniJournal of Zoology
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Typification of the name Senecio pygmaeus (Asteraceae), with some additional taxonomic and phytogeographic remarks

2023

A thorough research on the scientific activity of Guglielmo Gasparrini, Giovanni Gussone and Augustin Pyramus De Candolle allowed the authors to adress a research in several European herbaria looking for the type of the name Senecio pygmaeus DC. The original specimen sent by Gussone and mentioned in the protologue by Candolle is still kept at G-DC and is designated as the lectotype, whilst three other herbarium sheets, preserved at NAP-GUSS, PAL and PAV herbaria respectively, in all probability belong to the same gathering, and are considered as isolectotypes. The authors provide an updated description of this taxon in order to better point out its diagnostic characters. However, further bi…

EcologySettore BIO/02 - Botanica Sistematicabotanical exploration herbarium Mediterranean flora nomenclatural type Senecio leucanthemifolius Sicily taxonomy vascular floraPlant ScienceEcology Evolution Behavior and SystematicsMediterranean Botany
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First Record of the Genus Acanthixalus Laurent, 1944 from the Upper Guinean Rain Forest, West Africa, with the Description of a New Species

2003

Abstract We describe a new species of Acanthixalus from southwestern Ivory Coast. Acanthixalus sonjae sp. nov. differs from the Central African Acanthixalus spinosus genetically by 4.6 % in the investigated 16S rRNA. Morphologically adult frogs are very similar to A. spinosus. Male A. sonjae have wider heads and probably smaller gular glands than A. spinosus. Tadpoles of A. sonjae differ by much longer tails. Acanthixalus sonjae males are apparently mute. The new species is semiaquatic and lives in large water-filled cavities of trees in secondary and primary rain forest. Tadpoles complete metamorphosis in three months. They are at least partly carnivorous.

Ecologymedia_common.quotation_subjectRainforestBiologybiology.organism_classificationWest africaAcanthixalus spinosusGenusAcanthixalus sonjaeAnimal Science and ZoologyMetamorphosisAcanthixalusEcology Evolution Behavior and Systematicsmedia_commonJournal of Herpetology
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Case 3684Elasmostethus dorsalisJakovlev, 1876 (currentlyElasmucha dorsalis; Insecta, Heteroptera): proposed precedence overAcanthosoma vicinumUhler, …

2015

The purpose of this application, under Article 23.9.3 of the Code, is to conserve the widely used specific name Elasmucha dorsalis (Jakovlev, 1876) for a species of subsocial acanthosomatid bug from East Asia. The name is threatened by the senior subjective synonym Elasmucha vicina (Uhler, 1861), which has seldom been used since its first publication. Therefore, precedence of the name Elasmucha dorsalis (Jakovlev, 1876) is proposed.

ElasmostethusbiologyEcologyHeteropteraZoologyTaxonomy (biology)AcanthosomaAcanthosomatidaebiology.organism_classificationNomenclatureSpecific nameThe Bulletin of Zoological Nomenclature
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Taxonomic Status of Neoechinorhynchus Agilis (Acanthocephala, Neoechinorhynchidae), with a Description of two New Species of the Genus from the Atlan…

2014

2 Section of Hydrobiont Diseases, Pacifi c Research. Fisheries Center, Shevchenko str., 4, Vladivostok, 690950 Russia Taxonomic Status of Neoechinorhynchus agilis (Acanthocephala, Neoechinorhynchidae), with a De- scription of Two New Species of the Genus from the Atlantic and Pacifi c Mullets (Teleostei, Mugili- dae). Tkach, Ie. V., Sarabeev, V. L., Shvetsova, L. S. — Th e wide variability in morphological features, geographical and host ranges of mullet acanthocephalan parasite Neoechinorhynchus agilis (Rudolphi, 1819), raises the question of taxonomic status of this species. Rudolphi's type and Yamagutis voucher specimens, as well as our own material from the WW Pacifi c and NE Atlantic r…

EoacanthocephalamediterraneanZoologymugil cephaluscеверо-восточная атлан- ти каchelon labrosusMulletсредиземное мореAcanthocephalaGenusShevchenkoAnimaliaEcology Evolution Behavior and SystematicsTaxonomyTeleosteibiologyазово-черноморский бассейнMugilChelonBiodiversitybiology.organism_classificationNeoechinorhynchidaeNeoechinorhynchidaeazov-black seaQL1-991northeast atlanticAnimal Science and ZoologyAcanthocephalaZoologyNeoechinorhynchidaVestnik Zoologii
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