Search results for "Cape"

Il difficoltoso percorso del Piano paesaggistico siciliano

2020

Nel 1999, la Sicilia, con anticipo rispetto alle regioni ritenute all’avanguardia nella gestione del proprio territorio e del proprio paesaggio, aveva individuato nello strumento del Piano Paesaggistico il mezzo attraverso cui perseguire la protezione e la salvaguardia del proprio patrimonio culturale e naturale. Alla caparbia e avveduta intuizione però sono succeduti anni di lungaggini amministrative, di numerosi silenzi e scellerati colpi di spugna. Dopo ventun anni, sono finalmente stati adottati e approvati i piani paesistici di gran parte dei 17 ambiti identificati dal documento del 1999. E qual è la reazione di quei territori che frattanto, in un ventennio, hanno subito non pochi camb…

Investigating visual practices in educational settings : Schoolscapes, language ideologies and organizational cultures

2017

Isstahstischana kā no semmes wehl wairak augļus warr dabbuht nekā lihdsschim dabbuhts [Izstāstīšana kā no zemes vēl vairāk augļus var dabūt]

1836

Padomi laukkopībā, veterinārijā, ugunsdrošībā , mājturībā un dārzkopībā. Grāmatā kopā 1., 2. un 3. nodaļa, katrai sava paginācija – 16 lpp.

A Territorial Approach to the Production of Urban and Rural Landscape.

2018

The authors, starting from the examination of the historic data of Palermo landscapes on the south-east side, draws up an analysis of the landscape by illustrating the environmental characteristics and the intervention of man in its transformations. Therefore, determined by a certain point to refer to, the author, on the basis of archival, literary, and existing graphic documentation, has therefore sought to illustrate the evolution of the landscape in the geographical area of Maredolce while still presenting relations with the territory of Palermo. Examining the diaries at the end of the eighteenth century with the help of the water colored planks of the sites taking into account the great…

Interpolative mapping of mean precipitation in the Baltic countries by using landscape characteristics

2011

Maps of the long-term mean precipitation involving local landscape variables were generated for the Baltic countries, and the effectiveness of seven modelling methods was compared. The precipitation data were recorded in 245 meteorological stations in 1966–2005, and 51 location-related explanatory variables were used. The similarity-based reasoning in the Constud software system outperformed other methods according to the validation fit, except for spring. The multivariate adaptive regression splines (MARS) was another effective method on average. The inclusion of landscape variables, compared to reverse distance-weighted interpolation, highlights the effect of uplands, larger water bodies …

Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil Granulocytes

2021

Myeloid cell arginase-mediated arginine depletion with consecutive inhibition of T cell functions is a key component of tumor immune escape. Both, granulocytic myeloid-derived suppressor cells (G-MDSC) and conventional mature human polymorphonuclear neutrophil granulocytes (PMN) express high levels of arginase 1 and can act as suppressor cells of adaptive anti-cancer immunity. Here we demonstrate that pharmacological inhibition of PMN-derived arginase 1 not only prevents the suppression of T cell functions but rather leads to a strong hyperactivation of T cells. Human PMN were incubated in cell culture medium in the absence or presence of an arginase inhibitor. T cells from healthy donors w…

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

2019

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this "convergence" of adaptive immunity among different individuals remain poorly understood. To quantitatively describe epitope immunogenicity, here we propose a supervised machine learning framework generating probabilistic estimates of immunogenicity, termed "immunogenicity scores," based on the numerical features computed through sequence-based simulation approximating the molecular scanning process of peptides presented onto major histocompatibility complex (MHC) by the human T cell receptor (T…

The Linguistic Landscape of the Valencian Community: A Comparative Analysis of Bilingual and Multilingual Signs in Three Different Areas

2019

During the last decades, the promotion of multilingualism has been key when designing linguistic policies in Europe. Previous research studies have focused on how languages are employed in fields such as education, media, and urban sites, among others. Bearing all this in mind, the aim of this paper is to analyse the linguistic landscapes of three municipalities located in a bilingual region in Spain, that of the Valencian Community. Thus, issues such as language contact, language dominance, and the languages used by a number of institutions on private and public signs were examined. As for the method, over 140 pictures of language signs were taken in order to examine language contact, lang…

Retention forestry and biodiversity conservation: a parallel with agroforestry

2013

In forested landscapes two general management systems – retention forestry and agroforestry – have been proposed as potentially efficient components of landscape approaches to ease the conflict between biodiversity objectives and human needs. In two recent reviews, Gustafsson et al. (2012) and Lindenmayer et al. (2012) provide a global overview of current knowledge about the practice and ecological roles of retention forestry. A few years ago, Bhagwat et al. (2008) produced a similar review addressing the role of agroforestry in biodiversity conservation. Here we draw a parallel between research on the ecological effects of retention forestry and agroforestry. We argue that conservation sci…

Do native white-clawed crayfish impact macroinvertebrate assemblages in Mediterranean limestone headwaters?

2019

Crayfish are among the largest aquatic macroinvertebrates in rivers and streams. Their trophic ecology is important for the understanding of the functioning of benthic communities. This is relevant in key areas, such as headwaters, as they partly condition the processes occurring downstream. To shed light on the effects of native white-clawed crayfish,Austropotamobius pallipes, on local macroinvertebrate assemblages from running headwaters, a three-month mesocosm-based field study was designed. Collection and subsequent analysis of benthic samples under different crayfish density levels yielded a set of metrics indicative of short-term impacts at general and taxonomic scales. Neither signif…