Search results for "Caps"

Constructions with shell nouns in English: their dual role in information packaging

2018

Les construccions encapsuladores en anglès i la doble funció en l'emmagatzematge de la informació
 Aquest treball se centra en les propietats funcionals i estructurals d’un tipus de fórmules focals en anglès: les construccions del tipus N-be-that (Schmid 2001), com en The problem is that he is jealous, a les quals denominem fórmules amb encapsuladors (FFSNs, segons la denominació en anglès). La funció dels noms en aquest patró consisteix a crear closques conceptuals (Schmid 1997) dins de les quals s’encapsula el contingut proposicional, una operació afavorida pel vincle coreferencial que hi ha entre les dues parts del patró. Les dades proporcionades pel BNC mostren dues manifestacions …

Abstract nouns as metadiscursive shells in academic discourse

2018

El discurs acadèmic es caracteritza per l’abundància de noms abstractes, com ara anàlisi, recerca, procés, concepte, aproximació o rol. Considerats mecanismes cohesius, atès que el seu significat discursiu es determina per referència al context en què apareixen, han rebut denominacions diverses en la bibliografia anglosaxona (anaphoric, signaling, carrier, shell o metadiscursive nouns). A partir de les propostes de Schmid (2000) i Jiang i Hyland (2016, 2017), aquest article explora la funció metadiscursiva d’aquests noms com a encapsuladors d’informacions complexes en un corpus de resums acadèmics elaborats per estudiants universitaris per als seus Treballs de Final de Grau. El treball abor…

Nucleotide sequence of a ssRNA phage from Acinetobacter: kinship to coliphages.

2002

The complete nucleotide sequence of ssRNA phage AP205 propagating in Acinetobacter species is reported. The RNA has three large ORFs, which code for the following homologues of the RNA coliphage proteins: the maturation, coat and replicase proteins. Their gene order is the same as that in coliphages. RNA coliphages or Leviviridae fall into two genera: the alloleviviruses, like Qβ, which have a coat read-through protein, and the leviviruses, like MS2, which do not have this coat protein extension. AP205 has no read-through protein and may therefore be classified as a levivirus. A major digression from the known leviviruses is the apparent absence of a lysis gene in AP205 at the usual positio…

CAPS!Mārketinga komunikāciju nozīme zīmola virzīšanā.

2016

Bakalaura darba tēma ir “CAPS! mārketinga komunikāciju nozīme zīmola virzīšanā”. Bakalaura darba mērķis ir novērtēt un analizēt SIA “Taste CAPS!”mārketinga komunikāciju sistēmu un kāda ir tās nozīme CAPS! zīmola virzīšanā, kā arī atklāt sistēmas trūkumus un piedāvāt priekšlikumus CAPS! mārketinga komunikāciju sistēmas pilnveidei un zīmola attīstībai. Bakalaura darbs sastāv no 3 nodaļām. Pirmajā nodaļa ir apkopota informācija, kas iegūta, analizējot Latvijas un ārvalstu mārketinga speciālistu atziņas par mārketingu, zīmolu un mārketinga komunikāciju veidiem un līdzekļiem. Otrajā nodaļa tika novērtēts CAPS! zīmols un veikts CAPS! mārketinga komunikāciju izvērtējums. Trešajā nodaļa tika veikts…

Synthesis of mesoporous silica nanoparticles (MSNs) and encapsulation of cisplatin for targeted cancer therapies

2014

The aim of this PhD thesis is to elaborate mesoporous silica nanoparticles (MSNs) able to sustain the release of cisplatin into the intracellular compartments of solid tumors. The parametric study shows that morphological, structural and textural properties of MSNs-MCM-41, synthesized by sol-gel reaction by using TEOS as a silica source and CTAB as a structure-directing agent, depend on pH, stirring speed, temperature and extraction process of CTAB. The synthesis atmosphere has to be controlled in order to avoid the presence of ethanol and carbonate species which are responsible of necks between particles generating unstable suspensions of MSNs.MSNs were functionalized in order to control t…

PML nuclear body-residing proteins sequentially associate with HPV genome after infectious nuclear delivery.

2019

Subnuclear promyelocytic leukemia (PML) nuclear bodies (NBs) are targeted by many DNA viruses after nuclear delivery. PML protein is essential for formation of PML NBs. Sp100 and Small Ubiquitin-Like Modifier (SUMO) are also permanently residing within PML NBs. Often, large DNA viruses disassemble and reorganize PML NBs to counteract their intrinsic antiviral activity and support establishment of infection. However, human papillomavirus (HPV) requires PML protein to retain incoming viral DNA in the nucleus for subsequent efficient transcription. In contrast, Sp100 was identified as a restriction factor for HPV. These findings suggested that PML NBs are important regulators of early stages o…

Purified Membrane-Containing Procapsids of Bacteriophage PRD1 Package the Viral Genome

2009

Icosahedral-tailed double-stranded DNA (dsDNA) bacteriophages and herpesviruses translocate viral DNA into a preformed procapsid in an ATP-driven reaction by a packaging complex that operates at a portal vertex. A similar packaging system operates in the tailless dsDNA phage PRD1 (Tectiviridae family), except that there is an internal membrane vesicle in the procapsid. The unit-length linear dsDNA genome with covalently linked 5'-terminal proteins enters the procapsid through a unique vertex. Two small integral membrane proteins, P20 and P22, provide a conduit for DNA translocation. The packaging machinery also contains the packaging ATPase P9 and the packaging efficiency factor P6. Here we…

Coxsackievirus B3-Induced Cellular Protrusions: Structural Characteristics and Functional Competence▿†

2011

ABSTRACT Virus-induced alterations in cell morphology play important roles in the viral life cycle. To examine the intracellular events of coxsackievirus B3 (CVB3) infection, green monkey kidney (GMK) cells were either inoculated with the virus or transfected with the viral RNA. Various microscopic and flow cytometric approaches demonstrated the emergence of CVB3 capsid proteins at 8 h posttransfection, followed by morphological transformation of the cells. The morphological changes included formation of membranous protrusions containing viral capsids, together with microtubules and actin. Translocation of viral capsids into these protrusions was sensitive to cytochalasin D, suggesting the …

Viral Entry and Receptors

2007

General Applications of Viscoelastics

2000

The many and diverse physicochemical characteristics of viscoelastic substances impose both their desired and undesired effects clinically. As there is no single ideal substance to meet clinical stipulations, individual viscoelastic characteristics should be considered with respect to demand. Georg Eisner described viscoelastic agents as a tool for space-occupying measures (in tissues, in space or on surfaces) applied by the use of special techniques (Eisner, 1980; Eisner, 1983). In surgery, viscoelastic substances protect tissues and cells from mechanical trauma, serve to separate tissues, occupy space, break away adhesions, stop bleeding, coat, act as manipulative instruments and move tis…