Search results for "Carboni"

Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy

2006

The Cancer Imaging Program of the National Cancer Institute convened a workshop to assess the current status of hypoxia imaging, to assess what is known about the biology of hypoxia as it relates to cancer and cancer therapy, and to define clinical scenarios in which in vivo hypoxia imaging could prove valuable.Hypoxia, or low oxygenation, has emerged as an important factor in tumor biology and response to cancer treatment. It has been correlated with angiogenesis, tumor aggressiveness, local recurrence, and metastasis, and it appears to be a prognostic factor for several cancers, including those of the cervix, head and neck, prostate, pancreas, and brain. The relationship between tumor oxy…

X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors.

2015

1-N-Alkylated-6-sulfamoyl saccharin derivatives were prepared and assayed as carbonic anhydrase inhibitors (CAIs). During X-ray crystallographic experiments an unexpected hydrolysis of the isothiazole ring was evidenced which allowed us to prepare highly potent enzyme inhibitors with selectivity for some isoforms with medical applications.

Dosimetria ESR con alanina per adronterapia per protoni e ioni carbonio

2014

Are the determinants of CO2 emissions converging among OECD countries?

2013

This paper studies convergence in CO2emission intensity (CO2 emissions over GDP) among OECD countries over the period 1960-2008 based on its determinants, namely, energy intensity (energy consumption over GDP) and the so-called carbonisation index (CO2 emissions over energy consumption). We apply the Phillips and Sul (2007) methodology, which tests for the existence of convergence clubs. Our results highlight that differences in emission intensity convergence are more determined by differences in convergence of the carbonisation index rather than by differences in the dynamic convergence of energy intensity.

Protein expression profiles in Bathymodiolus azoricus exposed to cadmium

2019

Proteomic changes in the "gill-bacteria complex" of the hydrothermal vent mussel B. azoricus exposed to cadmium in pressurized chambers ((Incubateurs Pressurises pour l'Observation en Culture d'Animaux Marins Profonds - IPOCAMP) were analyzed and compared with the non-exposed control group. 2-D Fluorescence Difference Gel Electrophoresis (2D-DIGE) showed that less than 1.5% of the proteome of mussels and symbiotic bacteria were affected by a short-term (24 h) Cd exposure. Twelve proteins of the more abundant differentially expressed proteins of which six were up-regulated and six were down-regulated were excised, digested and identified by mass spectrometry. The identified proteins included…

Physiological advantages of dwarfing in surviving extinctions in high-CO2 oceans

2015

Excessive CO 2 in the present-day ocean-atmosphere system is causing ocean acidification, and is likely to cause a severe biodiversity decline in the future, mirroring effects in many past mass extinctions. Fossil records demonstrate that organisms surviving such events were often smaller than those before, a phenomenon called the Lilliput effect. Here, we show that two gastropod species adapted to acidified seawater at shallow-water CO 2 seeps were smaller than those found in normal pH conditions and had higher mass-specific energy consumption but significantly lower whole-animal metabolic energy demand. These physiological changes allowed the animals to maintain calcification and to parti…

Trends and patterns in the evolution of vascular plants: macroevolutionary implications of a multilevel taxonomic analysis

2010

Cascales-Minana, B., Munoz-Bertomeu, J., Ros, R., Segura, J. 2010: Trends and patterns in the evolution of vascular plants: macroevolutionary implications of a multilevel taxonomic analysis. Lethaia, 10.1111/j.1502-3931.2009.00212.x Studying the macroevolutionary patterns of vascular plants from the Silurian to the present-day provides a global record of plant life history. Evolutionary rates (origination, extinction and diversification) for families, orders, classes and divisions were analysed, as was abundance and richness for 21 time intervals. An accumulative analysis, based on the total plant fossil record, the accumulated extinctions and relative diversity, was also carried out. The d…

New insights into the reading of Paleozoic plant fossil record discontinuities

2011

Studying the discontinuity patterns of Paleozoic vascular plants provides a global vision of these key events from the multivariate methods viewpoint. Non-metric multidimensional scaling, detrended correspondence analysis and cluster analysis have been employed together with a set of diversity and abundance measures and an evaluation of the geologic constraints from the plant fossil record data. The results reveal four clear significant discontinuities in terms of taxonomic composition and record representativeness during the early-middle Devonian, Devonian–Carboniferous, Mississippian–Pennsylvanian and early-late Permian. Due to the controversial character of the plant fossil record data a…

Comportamento di nanocompositi PA6/CNT in flusso elongazionale non isotermo

2012

Si sono preparate fibre a matrice poliammidica caricate con CNT. Sono state utilizzate due diverse tipologie di CNT a differente fattore di forma e grado di purezza, ossidate mediante plasma di ossigeno. Le misure di viscosità elongazionale hanno evidenziato che l’introduzione della carica comporta un incremento della MS a fronte di una diminuzione della BSR per tutti i materiali caricati. La tipologia e la funzionalizzazione dei CNT hanno delle notevoli ricadute sul diverso comportamento reologico. Studi morfologici hanno evidenziato che dopo la funzionalizzazione si registrano livelli di dispersione, allineamento e adesione interfacciale più alti. La natura delle interazioni matrice-caric…

Lower Bashkirian fusulinoideans from the upper part of the Tagnana Formation (Carboniferous, NW Algeria)

2021

The upper member of the Tagnana Formation of the Djebel Bechar Group (informally the Tagnana-3 or Tagnana Ill member) yielded fusulinoideans and other related foraminifera of the genera Pseudoendothyra (rare), Pseudostajfella (Semistaffella) (rare), Millerella, Pseudonovel/a, Plectostaffella, Eostaffella and Mediocris. The presence of Eostaffellina (rare) and Endostaffella is doubtful. The difference between Millerella and Eostaffella cannot be adequately defined by evolute versus involute coiling. Pseudonovella Kireeva, 1949 is redefined to include Seminovella Rauzer-Chernousova, 1951. The foraminifera are from two samples, one from close to the top and the other from near the base of the …