Search results for "Carcinogen"

showing 10 items of 6867 documents

Prospective Validation of Facial Nerve Monitoring to Prevent Nerve Damage During Robotic Drilling

2019

Facial nerve damage has a detrimental effect on a patient's life, therefore safety mechanisms to ensure its preservation are essential during lateral skull base surgery. During robotic cochlear implantation a trajectory passing the facial nerve at <0.5 mm is needed. Recently a stimulation probe and nerve monitoring approach were developed and introduced clinically, however for patient safety no trajectory was drilled closer than 0.4 mm. Here we assess the performance of the nerve monitoring system at closer distances. In a sheep model eight trajectories were drilled to test the setup followed by 12 trajectories during which the ENT surgeon relied solely on the nerve monitoring system and…

medicine.medical_specialtylcsh:Surgery610 Medicine & healthENT surgeon03 medical and health sciences0302 clinical medicinerobotic surgerymedicineotorhinolaryngologic diseasesRobotic surgeryCochlear implantation610 Medicine & healthOriginal Research630 Agriculturebusiness.industrynerve stimulation electrodemonopolar and bipolarMonitoring systemlcsh:RD1-811Microcomputed tomography620 EngineeringFacial nerveneurophysiology monitoringSurgeryrobotic cochlear implantationRobotic systems030220 oncology & carcinogenesisSkull base surgery570 Life sciences; biologySurgerybusiness030217 neurology & neurosurgeryFrontiers in Surgery
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Peripheral facial palsy following ventriculoperitoneal shunt. The lesson we have learned

2018

The most frequent complications after shunt surgery are infective and obstructive. Other types are less common, and eventually occur due to technical errors during brain ventricular puncture, opening the intraperitoneal cavity or the tunnelling of the catheter between the two points. Although rare, there are well-reported complications related to the poor positioning of the distal catheter, with perforation of organs and tissues.We report a very rare case of a male patient with normal pressure hydrocephalus submitted to ventriculoperitoneal shunt. During tunnelling of the shunt stylet, a peripheral facial palsy due to injury to the extra cranial segment of the facial nerve occurred.To the b…

medicine.medical_specialtylcsh:SurgeryFacial nerve paralysis Normal pressure hydrocephalus Ventriculoperitoneal shunt complicationslcsh:RC346-42903 medical and health sciences0302 clinical medicineNormal pressure hydrocephalusmedicinelcsh:Neurology. Diseases of the nervous systemMastoid regionPeripheral facial palsybusiness.industrySettore MED/27 - Neurochirurgialcsh:RD1-811medicine.diseaseFacial nerveSurgeryStyletShunt (medical)Catheter030220 oncology & carcinogenesisSurgeryNeurology (clinical)Complicationbusiness030217 neurology & neurosurgery
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Surgical Management of Retraction Pockets: Does Mastoidectomy have a Role?

2021

Abstract Introduction Retraction pocket is a condition in which the eardrum lies deeper within the middle ear. Its management has no consensus in literature. Objective To assess the role of mastoidectomy in the management of retraction pockets added to a tympanoplasty. Methods Prospective study of patients with retraction pocket and referred to surgery. The patients were randomly assigned to two groups: one managed with tympanoplasty and mastoidectomy and the other group with tympanoplasty only. The minimum follow-up considered was 12 months. The outcomes were: integrity of eardrum, recurrence, and hearing status. Results This study included 43 patients. In 24 cases retraction occurred in t…

medicine.medical_specialtymastoidectomymedicine.medical_treatmentlcsh:MedicineMastoidectomyMastoidectomy Middle ear Ossiculoplasty Otitis media Tympanic membrane Tympanoplasty03 medical and health sciences0302 clinical medicinetympanoplastymedicineossiculoplasty030223 otorhinolaryngologyOriginal Researchtympanic membraneOssicular chainAir volumebusiness.industrylcsh:Rotitis mediaTympanoplastylcsh:Otorhinolaryngologylcsh:RF1-547Settore MED/32 - AudiologiaSurgerySettore MED/31 - Otorinolaringoiatriamedicine.anatomical_structureOtorhinolaryngologymiddle ear030220 oncology & carcinogenesisMiddle earbusinessEardrumHearing.statusRetraction pocketInternational Archives of Otorhinolaryngology
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Needs Assessment in Care of Adults With Anorectal Malformations and Exstrophy-Epispadias Complex in Germany

2018

Introduction: Medical needs of adults with anorectal malformations (ARM) and the exstrophy-epispadias complex (EEC) are not fully understood. Therefore, the aim of the study was to evaluate how affected individuals get along with the current national medical care and what their medical or social long-term requirements are. Patients and Methods: Between 11/2014-07/2016 all adult members (≥18 years, ARM n = 113, EEC n = 126) of the German self-help organizations SoMA e.V. and Blasenekstrophie/Epispadie e.V. were contacted via email or post and asked to fill out an anonymous online questionnaire regarding medical requirements, treatment satisfaction, daily life impairment and expectations rega…

medicine.medical_specialtymedia_common.quotation_subject030232 urology & nephrologyEmpathylong-term quality of life issuesDiseaseComputer-assisted web interviewingEpispadiasPediatrics03 medical and health sciences0302 clinical medicineanorectal malformation (ARM)Health caremedicineexstrophy-epispadias complex (EEC)medical aftercareOriginal Researchmedia_commonbusiness.industrySoft skillslcsh:RJ1-570lcsh:Pediatricsmedicine.diseasehealth careFamily planning030220 oncology & carcinogenesisFamily medicinePediatrics Perinatology and Child HealthNeeds assessmentbusinessFrontiers in Pediatrics
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Innovation in Neurosurgery: The Concept of Cognitive Mapping

2019

In recent years, advances in cortical-subcortical mapping, intraoperative neurophysiology, and neuropsychology have increased the ability to remove intrinsic brain tumors, expanding indications and maximizing the extent of resection. This has provided a significant improvement in progression-free survival, time of malignant transformation (in low-grade gliomas), and overall survival. Although current techniques enable preservation of language and motor functions during surgery, the maintenance of a complex set of functions defined with the term cognition is not always achievable. Cognition is defined as every neural process underlying a high human function and includes motor haptic and visu…

medicine.medical_specialtymedia_common.quotation_subjectElectric Stimulation TherapyEmpathyNeurosurgical ProceduresExecutive Function03 medical and health sciencesPostoperative ComplicationsSpatial ProcessingCognition0302 clinical medicineQuality of life (healthcare)HumansGlioma surgeryMedicineCognitive rehabilitation therapySet (psychology)media_commonBrain MappingCognitive mapBrain Neoplasmsbusiness.industryEloquent areaNeuropsychologyMargins of ExcisionCognitionGliomaSemantics030220 oncology & carcinogenesisNeuropsychological testsSurgeryNeurology (clinical)NeurosurgeryCognition DisordersbusinessOrgan Sparing Treatments030217 neurology & neurosurgeryCognitive psychologyWorld Neurosurgery
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Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue

2017

Fertility-preserving measures are becoming important for patients receiving oncological treatment. One method involves cryopreservation of ovarian tissue and transplanting it when treatment is completed. We report complications resulting from surgical and fertility medicine, and the results of procedures for the removal and transplantation of ovarian tissue carried out within the FertiProtekt network. A survey using a structured questionnaire was conducted among the FertiProtekt network centres between November 2015 and June 2016. The analysis included surgical techniques used to remove and transplant ovarian tissue, surgical complications and results. Laparoscopic removal and transplantati…

medicine.medical_specialtymedia_common.quotation_subjectFertilityOvaryMenstruation03 medical and health sciencesGynecologic Surgical Procedures0302 clinical medicinemedicineHumansFertility preservation610 Medicine & healthLaparoscopyOncofertilitymedia_common030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryOvaryFertility PreservationObstetrics and GynecologyCancermedicine.diseaseSurgeryTransplantationmedicine.anatomical_structureReproductive Medicine030220 oncology & carcinogenesisFemalebusinessDevelopmental BiologyReproductive BioMedicine Online
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The impact of medication-related osteonecrosis of the jaws on the quality of life in cancer patients

2020

Background To evaluate the impact of oral health on the quality of life (QOL) of individuals undergoing cancer treatment at the time of diagnosis of medication-related osteonecrosis of the jaw (MRONJ). Material and Methods The present cross-sectional study analyzed patients with MRONJ from 2013 to 2019. The collected data included demographic data, base disease, medications associated with MRONJ, route of administration and time of use, signs, symptoms, and tomographic features of acute MRONJ, staging according to American Association of Oral and maxillofacial Surgeons position paper 2014 (AAOMS), type of dental treatment performed, outcome, and the responses to the Oral Health Impact Profi…

medicine.medical_specialtymedia_common.quotation_subjectMEDLINEDisease03 medical and health sciencesRoute of administration0302 clinical medicineQuality of lifeInternal medicineMedicineGeneral Dentistrymedia_commonOral Medicine and Pathologybusiness.industryResearchMedical recordCancer030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesSAÚDE BUCAL030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASWorrybusinessOsteonecrosis of the jaw
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Longterm quality of life after oncologic surgery and microvascular free flap reconstruction in patients with oral squamous cell carcinoma

2016

Background Quality of life (QoL) has become increasingly important in cancer treatment. It refers to the patient’s perception of the effects of the disease and therapy, and their impact on daily functioning and general feeling of well being. Material and Methods n this prospective study, a total of 100 patients treated at our institution, completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and the specific EORTC QLQ-H&N35 module. The questionnaires were distributed to the patients between 12 and 60 months postoperatively. Results Global QoL score was 58.3 and mean score for functioning scale was 76.7. Fatigue (28.7 ± 26.1), followed by fina…

medicine.medical_specialtymedia_common.quotation_subjectOdontologíaDiseaseFree Tissue FlapsOncologic surgery03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesmedicineCarcinomaHumansProspective StudiesProspective cohort studyGeneral Dentistrymedia_commonMouth neoplasmOral Medicine and Pathologybusiness.industryGeneral surgeryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludhumanitiesSurgeryOtorhinolaryngologyFeeling030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellQuality of LifeFree flap reconstructionSurgeryMouth NeoplasmsbusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Outcome Quality Standards in Pancreatic Oncologic Surgery in Spain

2018

Introduction: To establish quality standards in oncologic surgery is a complex but necessary challenge to improve surgical outcomes. Unlike other tumors, there are no well-defined quality standards in pancreatic cancer. The aim of this study is to identify quality indicators in pancreatic oncologic surgery in Spain as well as their acceptable limits of variability. Methods: Quality indicators were selected based on clinical practice guidelines, consensus conferences, reviews and national publications on oncologic pancreatic surgery between the years 2000 and 2016. Variability margins for each indicator have been determined by statistical process control techniques and graphically represente…

medicine.medical_specialtymedia_common.quotation_subjectPancreatic surgery030230 surgeryOutcome (game theory)Oncologic surgeryPancreatic surgery03 medical and health sciencesPancreatectomy0302 clinical medicinePancreatic cancerOutcome Assessment Health CaremedicineHumansQuality (business)Quality standardsIntensive care medicinePancreasOncologic resectionQuality of Health Caremedia_commonbusiness.industryGeneral Engineeringmedicine.diseaseConfidence intervalPancreatic NeoplasmsSpainHomogeneousSample size determination030220 oncology & carcinogenesisbusinessCirugía Española (English Edition)
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From Illusion to Reality: A Brief History of Robotic Surgery.

2018

Purpose. Robotic surgery is currently employed for many surgical procedures, yielding interesting results. Methods. We performed an historical review of robots and robotic surgery evaluating some critical phases of its evolution, analyzing its impact on our life and the steps completed that gave the robotics its current popularity. Results. The origins of robotics can be traced back to Greek mythology. Different aspects of robotics have been explored by some of the greatest inventors like Leonardo da Vinci, Pierre Jaquet-Droz, and Wolfgang Von-Kempelen. Advances in many fields of science made possible the development of advanced surgical robots. Over 3000 da Vinci robotic platforms are ins…

medicine.medical_specialtymedia_common.quotation_subjecthistory of medicineIllusionsurgical educationHistory of medicineHistory 18th CenturyHistory 21st Century03 medical and health sciencesAutomation0302 clinical medicineRobotic Surgical Proceduresrobotic surgerymedicineHumansRobotic surgeryMedical physicsHistory Ancientmedia_commonHistory 15th Centurybusiness.industryNOTESRobotic Surgical ProceduresHistory 19th CenturySurgical proceduresHistory 20th CenturyHistory Medieval030220 oncology & carcinogenesisRobot030211 gastroenterology & hepatologySurgerySurgical educationbusinessHumanSurgical innovation
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