Search results for "Carcinoma"
showing 10 items of 3529 documents
TP53 mutations and S-phase fraction but not DNA-ploidy are independent prognostic indicators in laryngeal squamous cell carcinoma
2005
To prospectively evaluate the prognostic significance of TP53, H-, K-, and N-Ras mutations, DNA-ploidy and S-phase fraction (SPF) in patients affected by locally advanced laryngeal squamous cell carcinoma (LSCC). Eight-one patients (median follow-up was 71 months) who underwent resective surgery for primary operable locally advanced LSCC were analyzed. Tumor DNA was screened for mutational analysis by PCR/SSCP and sequencing. DNA-ploidy and SPF were performed by flow cytometric analyses. Thirty-six patients (44%) had, at least, a mutation in the TP53 gene. Of them, 22% (8/36) had double mutations and 3% (1/36) had triple mutations. In total, 46 TP53 mutations were observed. The majority (41…
Tumor-associated tissue eosinophilia in tongue squamous cell carcinoma
2020
Tumoren der Ceruminaldrüsen
1987
Tumours originating from the ceruminous glands can be classified into five types: adenomas, adenocarcinomas, adenoid-cystic carcinomas, pleomorphic adenomas and mucoepidermoid carcinomas. The diagnosis is based on histological findings and can be quite difficult if the tumour status has to be determined. Classification into one of the five types of tumours may be facilitated at times by studying the clinical pattern. Three case reports are quoted as examples to illustrate that neoplasias originating from the ceruminous glands can assume considerable proportions and must be considered in differential diagnosis when assessing space-occupying growths in the soft tissue of the neck. Whereas pro…
Mandibular metastasis from carcinoma of the bladder: Report of a case and literature review
2022
Metastases represent about 1% of all malignant tumors of the oral region. Only 12 cases of metastases to the jawbones and 3 to the oral soft tissues from a carcinoma of the bladder are reported in the English literature. Here we report a case of an 86 year-old man with a metastasis to the anterior region of the lower jaw from a transitional cell carcinoma of the bladder treated 5 years before, all-together with a literature review.
Prostatic adenocarcinoma with mandibular metastatic lesion : case report
2007
Metastatic lesions of primary tumors, which originate in different parts of the body, comprise almost 1 % of different types of oral cancers. These lesions can affect either bones or soft tissues in the maxillofacial region. Whenever the maxillofacial area is affected, the most common location is in the molar region of the mandible. The clinical presentation of mandibular metastasis follows a clinical pattern characterized by irradiated dental pain in the third molar region. The most frequent sign is parethesia of the area innervated by the mandibular alveolar dental nerve. Differential diagnosis and treatment of these patients can be extremely difficult because there a number of pathologic…
A case report of coexistence of a sialolith and an adenoid cystic carcinoma in the submandibular gland
2006
Ôhe occurrence of sialoliths in the submandibular gland is 80% due to the specific anatomy of both the gland and its duct. The diagnosis is rather easy because of the obvious clinical signs of the entity. Imaging studies are always necessary in order to treat the patient as effectively as possible. The stones do not tend to occur within the gland as frequently as in the respective duct. The coexistence of sialoliths and malignant tumors is extremely rare. A 70-year-old woman with intraparenchymal stone was operated in our ENT department. In addition to the sialolith the pathological examination revealed the existence of an adenoid cystic carcinoma (ACC), that extended to the neighboring ske…
Valutazione del potenziale anticancro del frutto di Mangifera indica proveniente dalle aree rurali siciliane
2022
Advances in the endoscopic management of malignant biliary obstruction
2020
Biliary obstruction is common in pancreatobiliary malignancies and has a negative impact on the patient’s quality of life, postoperative complications, and survival rates. Particularly in the last decade, there has been enormous progress regarding the diagnostic and therapeutic options in patients with malignant biliary obstruction. Endoscopy has given a new insight in this direction and novel techniques have been developed for the better characterization and treatment of malignant strictures. We herein summarize the available data on the different endoscopic techniques, and clarify their role in the diagnosis and treatment of malignant biliary obstructive disease. Finally, we propose an al…
Evolución de la incidencia y de la supervivencia del carcinoma broncogénico en la provincia de Castellón en el periodo de tiempo comprendido entre 20…
2022
El carcinoma broncogénico (CB) es el más frecuente a nivel mundial y el más letal en ambos sexos. La incidencia del CB varía no sólo entre países sino también entre distintas zonas de un mismo país. Dado que la OMS recomienda disponer de estrategias de lucha contra el cáncer, creemos que analizar su situación en una zona geográfica dada puede contribuir a establecer una correcta planificación sanitaria. En consecuencia, hemos planteado el presente trabajo con los principales objetivos de: 1.- Conocer las principales características anatomopatológicas, clínicas, y epidemiológicas del CB en la provincia de Castellón entre 2004 y 2017. 2.- Analizar la evolución en este tiempo de las tasas de i…
La quimioembolización transarterial en el tratamiento del carcinoma hepatocelular en estadio intermedio. Estudio de los factores predictivos de super…
2014
La QETA es actualmente el tratamiento de elección del CHC en estadio intermedio de la BCLC. A pesar de ser la terapia más utilizada, existen múltiples aspectos por dilucidar, principalmente la identificación de los mejores candidatos dentro del amplio y heterogéneo grupo de pacientes que componen el estadio intermedio. Los objetivos primarios de este estudio han sido establecer la supervivencia global y actuarial asociada al tratamiento con QETA e identificar los factores predictivos de supervivencia mientras que como objetivos secundarios se han analizado la respuesta tumoral completa y objetiva, la supervivencia libre de enfermedad y la seguridad de la terapia. Entre mayo de 2002 y junio …