Search results for "Cardiac"

Ventricular arrhythmias in children: The uselessness of MRI

2008

Color superposition: a new modality for contrast echocardiography.

1987

To improve the estimation of endocardial borders in echocardiography, a technique has been developed to combine images from contrasted and noncontrasted echocardiograms of the same heart-phase using a color superposition mode. This method allows both experienced as well as less experienced examiners to define the endocardial borders more reproducibly and objectively. This is achieved by displaying tissue structures as gray level images while the ventricular cavity is marked selectively by the color display of the contrast material zone. Results of volume estimations of the left ventricle by different examiners using several imaging modes including color superposition display are presented.

An atlas- and data-driven approach to initializing reaction-diffusion systems in computer cardiac electrophysiology

2016

The cardiac electrophysiology (EP) problem is governed by a nonlinear anisotropic reaction-diffusion system with a very rapidly varying reaction term associated with the transmembrane cell current. The nonlinearity associated with the cell models requires a stabilization process before any simulation is performed. More importantly, when used in a 3-dimensional (3D) anatomy, it is not sufficient to perform this stabilization on the basis of isolated cells only, since the coupling of the different cells through the tissue greatly modulates the dynamics of the system. Therefore, stabilization of the system must be performed on the entire 3D model. This work develops a novel procedure for the i…

Étude de la Dynamique des Ondes Spirales à l'Échelle Cellulaire par Modèles Expérimental et Numérique

2012

Among the death due to the cardiac problems, the arrhythmias play a major role, particularly the atrial disorders. This alarming situation attracts an intense research, but it is still limited by the availability of experimental models to reproduce the triggering mechanisms of arrhythmias at the cellular level and extensions of these anomalies. Whether they occur on a healthy or pathological heart, or they are benign or potentially dangerous (risk of sudden death), the arrhythmias constitute an important chapter of the cardiology. This thesis is interested in the studying and modeling of the arrhythmias at a cellular scale. Thus the problems of this thesis can be summarized briefly by the f…

Definition of a mutual reference shape based on information theory and active contours

2013

In this paper, we propose to consider the estimation of a reference shape from a set of different segmentation results using both active contours and information theory. The reference shape is then defined as the minimum of a criterion that benefits from both the mutual information and the joint entropy of the input segmentations. This energy criterion is here justified using similarities between information theory quantities and area measures, and presented in a continuous variational framework. This framework brings out some interesting evaluation measures such as the specificity and sensitivity. In order to solve this shape optimization problem, shape derivatives are computed for each te…

Leveraging Uncertainty Estimates to Improve Segmentation Performance in Cardiac MR

2021

International audience; In medical image segmentation, several studies have used Bayesian neural networks to segment and quantify the uncertainty of the images. These studies show that there might be an increased epistemic uncertainty in areas where there are semantically and visually challenging pixels. The uncertain areas of the image can be of a great interest as they can possibly indicate the regions of incorrect segmentation. To leverage the uncertainty information, we propose a segmentation model that incorporates the uncertainty into its learning process. Firstly, we generate the uncertainty estimate (sample variance) using Monte-Carlo dropout during training. Then we incorporate it …

Using Polynomial Loss and Uncertainty Information for Robust Left Atrial and Scar Quantification and Segmentation

2022

Automatic and accurate segmentation of the left atrial (LA) cavity and scar can be helpful for the diagnosis and prognosis of patients with atrial fibrillation. However, automating the segmentation can be difficult due to the poor image quality, variable LA shapes, and small discrete regions of LA scars. In this paper, we proposed a fully-automatic method to segment LA cavity and scar from Late Gadolinium Enhancement (LGE) MRIs. For the loss functions, we propose two different losses for each task. To enhance the segmentation of LA cavity from the multicenter dataset, we present a hybrid loss that leverages Dice loss with a polynomial version of cross-entropy loss (PolyCE). We also utilize …

Left-Ventricle Segmentation of SPECT Images of Rats

2015

Single-photon emission computed tomography (SPECT) imaging of the heart is helpful to quantify the left-ventricular ejection fraction and study myocardial perfusion scans. However, these evaluations require a 3-D segmentation of the left-ventricular wall on each phase of the cardiac cycle. This paper presents a fast and interactive graph cut method for 3-D segmentation of the left ventricle (LV) of rats in SPECT images. The method is carried out in three steps. First, 3-D sampling of the LV cavity is made in a spherical-cylindrical coordinate system. Then, a graph-cut-based energy minimization procedure provides delineation of the myocardium centerline surface. From there, it is possible to…

Walk tests : a standardizable tool to assess capacities in cardio-vascular disease

2011

Cardiovascular and cerebrovascular diseases remain the first cause of mortality and handicap in the world. With the improvements in the management of the acute phase, the number of patients with limited exercise capacity due to chronic cardiovascular disease is increasing. The aim of this thesis was to conduct a thorough study of the use of standardized walk tests to assess exercise capacity in coronary artery disease patients. We first explain the concepts of handicap and quality of life in chronic diseases, and the need for functional evaluations in order to assess their impact and evolution. We then present the current modalities of cardiac rehabilitation, emphasizing the importance of p…

Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction

2015

Up to 80% of individuals with myotonic dystrophy type 1 (DM1) will develop cardiac abnormalities at some point during the progression of their disease, the most common of which is heart blockage of varying degrees. Such blockage is characterized by conduction defects and supraventricular and ventricular tachycardia, and carries a high risk of sudden cardiac death. Despite its importance, very few animal model studies have focused on the heart dysfunction in DM1. Here, we describe the characterization of the heart phenotype in a Drosophila model expressing pure expanded CUG repeats under the control of the cardiomyocyte-specific driver GMH5-Gal4. Morphologically, expression of 250 CUG repeat…