Search results for "Cardiac"

showing 10 items of 1495 documents

Chemical partitioning and DNA fingerprinting of some pistachio (Pistacia vera L.) varieties of different geographical origin

2019

The genus Pistacia (Anacardiaceae family) is represented by several species, of which only P. vera L. produces edible seeds (pistachio). Despite the different flavor and taste, a correct identification of pistachio varieties based on the sole phenotypic character is sometimes hard to achieve. Here we used a combination of chemical partitioning and molecular fingerprinting for the unequivocal identification of commercial pistachio seed varieties (Bronte, Kern, Kerman, Larnaka, Mateur and Mawardi) of different geographical origin. The total phenolic content was higher in the variety Bronte followed by Larnaka and Mawardi cultivars. The total anthocyanin content was higher in Bronte and Larnak…

Anthocyanin0106 biological sciencesAnacardiaceaePlant ScienceHorticulture01 natural sciencesBiochemistryAnthocyaninsLinoleic Acidchemistry.chemical_compoundSettore BIO/10 - BiochimicaProanthocyanidinsAnacardiaceaeCultivarFatty acidsMolecular BiologyPhylogenyFlavonoidsPistacia veraSeedGeographyPistaciabiology010405 organic chemistryInternal transcribed spacer (ITS)General MedicineFatty acidbiology.organism_classificationDNA Fingerprinting0104 chemical sciencesHorticultureAnacardiaceae; Anthocyanins; Fatty acids; Flavonoids; Internal transcribed spacer (ITS); Pistacia vera; Proanthocyanidins; Biochemistry; Molecular Biology; Plant Science; HorticultureProanthocyanidinchemistryDNA profilingAnthocyaninPistacia lentiscusPistaciaSeedsFlavonoidProanthocyanidinMolecular FingerprintingOleic Acid010606 plant biology & botanyPhytochemistry
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CardioPulse: developments in the treatment of aortic aneurysms in 2014

2015

Since the introduction of EndoVascular Aortic Repair (EVAR) for the treatment of abdominal aortic aneurysms (AAA) more than 20 years ago, the technique has evolved rapidly, from tubular grafts for fairly simple abdominal aortic anatomy, to bifurcated, fenestrated, branched, or parallel grafts for complex aortic aneurysms, no longer confined to the infrarenal abdominal aorta.

Aortic Aneurysm ThoracicAortic RuptureEndovascular ProceduresBiomedical Technology610 Medicine & healthEquipment DesignSettore MED/22 - Chirurgia Vascolare2705 Cardiology and Cardiovascular MedicineBlood Vessel Prosthesis10020 Clinic for Cardiac SurgeryBlood Vessel Prosthesis ImplantationHumansaortic aneurysmAortic Aneurysm Abdominal
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RUPTURE OF AN AORTIC DISSECTION INTO THE RIGHT ATRIUM IN A PATIENT WITH PREVIOUS AORTIC VALVE REPLACEMENT: A CASE REPORT

2005

We report the case of a 73-year-old man with a history of previous aortic valve replacement in 1990 and rupture of an aortic dissection into the right atrium. The patient was admitted to the emergency room because of chest pain, stopped not long after. The electrocardiogram did not show any signs of ischemia and myocardial enzymes were not increased. Transthoracic echocardiography revealed aortic root dilation (maximum diameter 60 mm) extended to the aortic arch, and the presence of a flow from the ascending aorta to the right atrium (evocative of a fistula between the two chambers). The aortic valvular prosthesis function was good. Transesophageal echocardiography confirmed an aorta-right …

Aortic aneurysmFistulaAortic dissectionAscending aortaCardiac surgeryShunts.
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Focus on the unique mechanisms involved in thoracic aortic aneurysm formation in bicuspid aortic valve versus tricuspid aortic valve patients: clinic…

2013

OBJECTIVES: The involvement of different factors in the onset of thoracic aortic aneurysm (TAA) in patients with a bicuspid aortic valve (BAV) vs those with a tricuspid aortic valve (TAV) is well recognized. However, the molecular, genetic and cellular mechanisms driving TAA remain unclear. The aim of this study was to identify the different mechanisms involved in TAA development in patients with BAV vs TAV. METHODS: Aorta specimens and DNA samples were collected from 24 BAV (18 men and 6 women; mean age: 54.2 ± 14.39 years) and 110 TAV (79 men and 31 women, mean age: 66 ± 9.8 years) patients. A control group of 128 subjects (61 men and 67 woman, mean age: 61.1 ± 5.8 years) was also enrolle…

Aortic valveMaleThoracicHeart Valve DiseasesApoptosisPilot ProjectsBicuspid aortic valve; Clinical implications; Identifying different genetic and histological profiles; Thoracic aortic aneurysm; Tricuspid aortic valve; Adult; Aged; Aortic Aneurysm Thoracic; Aortic Valve; Apoptosis; Comorbidity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heart Valve Diseases; Histocytochemistry; Humans; Male; Matrix Metalloproteinase 9; Middle Aged; Pilot Projects; Polymorphism Single Nucleotide; Risk Factors; Tricuspid ValveComorbidityBicuspid aortic valveBicuspid Aortic Valve DiseaseGene FrequencyFibrosisRisk FactorsClinical implicationsTricuspid valvebiologyHistocytochemistryGeneral MedicineSingle NucleotideMiddle AgedAortic Aneurysmmedicine.anatomical_structureMatrix Metalloproteinase 9Aortic ValveCardiologyFemaleTricuspid ValveCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineAdultmedicine.medical_specialtyBicuspid aortic valveGenotypeThoracic aortic aneurysmTricuspid aortic valvePolymorphism Single Nucleotidemedicine.arteryInternal medicineThoracic aortic aneurysmAscending aortamedicineSettore MED/05 - Patologia ClinicaHumansGenetic Predisposition to DiseasePolymorphismIdentifying different genetic and histological profilesAgedAortaAortic Aneurysm Thoracicbusiness.industryAngiotensin-converting enzymeSettore MED/23 - Chirurgia Cardiacamedicine.diseasebiology.proteinSurgerybusinessEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
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Outcomes of aortic valve repair according to valve morphology and surgical techniques

2012

OBJECTIVES: The aim of this study was to assess the impact of aortic valve morphology and different surgical aortic valve repair techni- ques on long-term clinical outcomes. METHODS: Between February 2003 and May 2010, 216 patients with aortic insufficiency underwent aortic valve repair in our institu- tion. Ages ranged between 26 and 82 years (mean 53 ± 15 years). Aortic valve dysfunctions, according to functional classification, were: type I in 55 patients (25.5%), type II in 126 (58.3%) and type III in 35 (16.2%). Sixty-six patients (27.7%) had a bicuspid valve. Aortic valve repair techniques included sub-commissural plasty in 138 patients, plication in 84, free-edge reinforcement in 80,…

Aortic valveMaleTime Factorsmedicine.medical_treatmentKaplan-Meier EstimateAortic valve repairRecurrenceRisk FactorsMitral valve80 and overHospital MortalityCoronary Artery BypassAortaUltrasonographyAged 80 and overTricuspid valveCalcinosisCardiac Valve AnnuloplastyMiddle AgedAortic valve repair • Bicuspid aortic valve • Tricuspid aortic valve • Aortic annulus stabilization medicine.anatomical_structureTreatment OutcomeAortic ValveReplantationcardiovascular systemCardiologyChordae TendineaeMitral ValveFemaleChordae tendineaeCardiology and Cardiovascular MedicineAdult; Aged; Aged 80 and over; Aorta; Aortic Valve; Aortic Valve Insufficiency; Blood Vessel Prosthesis Implantation; Calcinosis; Chordae Tendineae; Coronary Artery Bypass; Disease-Free Survival; Female; Hospital Mortality; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mitral Valve; Proportional Hazards Models; Recurrence; Replantation; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography; Cardiac Valve Annuloplasty; Suture TechniquesPulmonary and Respiratory MedicineAdultmedicine.medical_specialtyAortic Valve InsufficiencyRisk AssessmentCardiac Valve AnnuloplastyDisease-Free SurvivalBlood Vessel Prosthesis ImplantationBicuspid valveInternal medicinemedicineHumansAgedProportional Hazards ModelsMitral valve repairbusiness.industrySuture TechniquesSettore MED/23 - Chirurgia CardiacaOriginal ArticlesSurgerySurgerybusiness
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A multicentre European registry to evaluate the Direct Flow Medical transcatheter aortic valve system for the treatment of patients with severe aorti…

2016

Aims Our aim was to assess the clinical outcomes of the Direct Flow Medical Transcatheter Aortic Valve System (DFM-TAVS), when used in routine clinical practice. Methods and results This is a prospective, open-label, multicentre, post-market registry of patients treated with DFM-TAVS according to approved commercial indications. Echocardiographic and angiographic data were evaluated by an independent core laboratory and adverse events were adjudicated and classified according to VARC-2 criteria by an independent clinical events committee. The primary endpoint was freedom from all-cause mortality at 30 days post procedure. Secondary endpoints included procedural, early safety and efficacy en…

Aortic valveMalemedicine.medical_specialtyCardiac Catheterizationmedicine.medical_treatmentAortic Valve InsufficiencyRegurgitation (circulation)030204 cardiovascular system & hematologyTranscatheter Aortic Valve Replacement03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineClinical endpointHumans030212 general & internal medicineHeart valveProspective StudiesRegistriesCardiac catheterizationAgedAged 80 and overHeart Valve Prosthesis Implantationbusiness.industryAortic Valve Stenosismedicine.disease3. Good healthClinical trialStenosismedicine.anatomical_structureTreatment OutcomeAortic valve stenosisAortic ValveHeart Valve ProsthesisCardiologyFemaleCardiology and Cardiovascular MedicinebusinessEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Echocardiographic and angiographic evaluation of left ventricular function during percutaneous transluminal aortic valvuloplasty.

1992

Transesophageal echocardiography was used to study the effect of the balloon inflation on left ventricular function in 20 patients with critical aortic stenosis undergoing balloon valvuloplasty. Balloon inflation caused an increase of end-diastolic (15% to 34%) and end-systolic (57% to 72%) left ventricular volume. Left ventricular wall stress increased from 30 +/- 10 x 10(3) dyn/cm2 at diastole and 121 +/- 40 x 10(3) dyn/cm2 at systole to 44 +/- 11 x 10(3) dyn/cm2 and 191 +/- 55 x 10(3) dyn/cm2, respectively, when the balloon was inflated (P less than 0.05). Turbulent regurgitant jet across the mitral valve increased from 15 +/- 2% to 25 +/- 3% during balloon inflation (P less than 0.01). …

Aortic valveMalemedicine.medical_specialtymedicine.medical_treatmentDiastoleMyocardial InfarctionBalloonCoronary AngiographyVentricular Function LeftCatheterizationRisk FactorsMitral valveInternal medicineCoronary CirculationmedicineHumansSystoleCardiac OutputAgedAged 80 and overbusiness.industryHemodynamicsMitral Valve InsufficiencyBlood flowAortic Valve StenosisMiddle Agedmedicine.diseaseAortic valvuloplastyStenosismedicine.anatomical_structureEchocardiographyAortic Valvecardiovascular systemCardiologyFemaleCardiology and Cardiovascular MedicinebusinessCatheterization and cardiovascular diagnosis
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Early structural degeneration of Mitroflow aortic valve: Another issue in addition to the mismatch?

2018

We reported two cases of early structural valve degeneration (SVD) with Mitroflow prosthesis in aortic position in patients above the age of 65 years. Microscopic aspects have been analysed to investigate the intrinsic mechanism of SVD. New techniques to improve the structure and the preservation of this prosthesis are needed in order to reduce potential dangerous early complications.

Aortic valvePulmonary and Respiratory Medicinemedicine.medical_specialtyAortic stenosimedicine.medical_treatmentCase ReportDegeneration (medical)030204 cardiovascular system & hematologyProsthesisStructural valve degeneration (SVD); aortic stenosis; prosthesis03 medical and health sciences0302 clinical medicineInternal medicinemedicineStructural valve degeneration (SVD)ProsthesiSettore MED/05 - Patologia ClinicaIn patient030212 general & internal medicineAortic stenosis; Prosthesis; Structural valve degeneration (SVD); Pulmonary and Respiratory Medicinebusiness.industryaortic stenosisSettore MED/23 - Chirurgia Cardiacamedicine.anatomical_structureCardiologyprosthesisbusiness
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Transcatheter Heart Valve Implantation in Bicuspid Patients with Self-Expanding Device

2021

Bicuspid aortic valve (BAV) patients are conventionally not treated by transcathether aortic valve implantation (TAVI) because of anatomic constraint with unfavorable outcome. Patient-specific numerical simulation of TAVI in BAV may predict important clinical insights to assess the conformability of the transcathether heart valves (THV) implanted on the aortic root of members of this challenging patient population. We aimed to develop a computational approach and virtually simulate TAVI in a group of n.6 stenotic BAV patients using the self-expanding Evolut Pro THV. Specifically, the structural mechanics were evaluated by a finite-element model to estimate the deformed THV configuration in …

Aortic valveTechnologymedicine.medical_specialtybicuspid aortic valveQH301-705.5medicine.medical_treatment0206 medical engineeringDiastoleBioengineering02 engineering and technology030204 cardiovascular system & hematologyBicuspid aortic valve Finite-element analysis Fluid–solid interaction Transcatheter aortic valve implantationArticle03 medical and health sciences0302 clinical medicineBicuspid aortic valveInternal medicinemedicine.arterymedicineCardiac skeletonHeart valveBiology (General)transcatheter aortic valve implantationAortabusiness.industryTSettore ING-IND/34 - Bioingegneria IndustrialeStentmedicine.diseasefluid–solid interaction020601 biomedical engineeringAortic wallmedicine.anatomical_structurefinite-element analysiscardiovascular systemCardiologybusinessBioengineering
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TAVI imaging: over the echocardiography

2020

Aortic valve stenosis (AS) is a common valvular heart disease. Recently, transcatheter aortic valve implantation (TAVI) has changed the treatment of severe AS in elderly patients with contraindications to traditional surgical replacement. Echocardiography is conventionally used as the first imaging modality to assess the presence and severity of AS and to provide anatomical and functional information. Nowadays, imaging techniques play a crucial role in the planning of TAVI to define suitable candidates. Computed tomography (CT) is essential to display the anatomy of the aortic valve complex (including aortic annulus, Valsalva sinuses, coronary arteries ostia, sinotubular junction), thoracoa…

Aortic valvemedicine.medical_specialtyAortic valve stenosisCoronary Angiography030218 nuclear medicine & medical imagingTranscatheter Aortic Valve Replacement03 medical and health sciences0302 clinical medicineMagnetic resonance imagingmedicineHumansRadiology Nuclear Medicine and imagingCardiac skeletonComputed tomographyNeuroradiologyAgedIncidental FindingsTranscatheter aortic valve implantationmedicine.diagnostic_testbusiness.industryvalvular heart diseaseSettore ING-IND/34 - Bioingegneria IndustrialeMagnetic resonance imagingInterventional radiologyGeneral Medicinemedicine.diseaseCoronary arteriesmedicine.anatomical_structureEchocardiography030220 oncology & carcinogenesisAortic valve stenosiscardiovascular systemRadiologybusinessTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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