Search results for "Case-control study"

showing 10 items of 563 documents

Physical inactivity in patients with COPD, a controlled multi-center pilot-study

2010

Physical activity (PA) has been reported to be reduced in severe chronic obstructive pulmonary disease (COPD). Studies in moderate COPD are currently scarce. The aim of the present study was to investigate physical activity in daily life in patients with COPD (n=70) and controls (n=30).A multi-center controlled study was conducted. PA was assessed using a multisensor armband device (SenseWear, BodyMedia, Pittsburgh, PA) and is reported as the average number of steps per day, and the time spent in mild and moderate physical activity.Patients suffered from mild (n=9), moderate (n=28), severe (n=23) and very severe (n=10) COPD. The time spent in activities with mild (80 + or - 69 min vs 160 + …

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyActivities of daily livingPilot ProjectsSettore MED/10 - Malattie Dell'Apparato RespiratorioMotor ActivitySeverity of Illness IndexArticlePulmonary Disease Chronic ObstructiveForced Expiratory VolumeSeverity of illnessActivities of Daily LivingMedicineCOPDHumansIn patientCOPD Physical activityAgedCOPDAnalysis of Variancebusiness.industryPhysical activityDisease progressionRespiratory diseaseCase-control studyStepsMiddle Agedmedicine.diseaseActivity monitorItalyCase-Control StudiesPhysical therapyDisease ProgressionExercise TestEnergy expenditureFemaleAnalysis of variancebusiness
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Alternative ways of expressing FEV1 and mortality in elderly people with and without COPD

2013

Expressing forced expiratory volume in 1 s (FEV1) as % predicted relies on the assumption of proportional variability and generalisability of prediction equations that may be unrealistic, especially for elderly people. We evaluated the prognostic implications of alternative ways of expressing FEV1. We enrolled 318 patients with chronic obstructive pulmonary disease (COPD) and 475 controls in the Salute Respiratoria nell'Anziano (SARA) study. The risk for 5-, 10- and 15-year mortality associated with FEV1 was studied by expressing FEV1 % pred, standardised by height cubed (FEV1 · Ht(-3)) and as a multiple of the sex-specific first percentile (FEV1 quotient (FEV1Q)). In the group with COPD, t…

Pulmonary and Respiratory MedicineSpirometryMalemedicine.medical_specialtyPediatricsPercentilePrognosiPulmonary diseaseSettore MED/10 - Malattie Dell'Apparato RespiratorioRate ratioPulmonary Disease Chronic ObstructiveElderly populationInternal medicineForced Expiratory VolumeHumansMedicineElderly peopleRespiratory Function TestAgedCOPDmedicine.diagnostic_testbusiness.industryRespiratory Function Tests; Spirometry; Humans; Treatment Outcome; Prognosis; Case-Control Studies; Aged; Middle Aged; Forced Expiratory Volume; Male; Female; Pulmonary Disease Chronic ObstructiveCase-control studyrespiratory systemMiddle AgedPrognosismedicine.diseaseRespiratory Function Testsrespiratory tract diseasesTreatment OutcomeSpirometryCase-Control StudiesFemalebusinessCase-Control StudieHuman
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Risk factors and effectiveness of preventive measures against influenza in the community

2012

Please cite this paper as: Castilla et al. (2013) Risk factors and effectiveness of preventive measures against influenza in the community. Influenza and Other Respiratory Viruses 7(2) 177–183. Background  The role of different risk exposures and preventive measures against influenza has not been well established. Objective  The aim of this study was to evaluate risk factors and measures to prevent influenza infection in the community. Methods  We conducted a multicenter case–control study. Cases were 481 outpatients aged 18 years or older with laboratory-confirmed influenza A(H1N1)09 in the 2009–2010 season in Spain. A control was selected for each case from outpatients from the same area …

Pulmonary and Respiratory Medicinemedicine.medical_specialtyHand washingEpidemiologybusiness.industryPublic healthMedical recordPublic Health Environmental and Occupational HealthCase-control studyVaccinationInfectious DiseasesEnvironmental healthEpidemiologyImmunologyHealth caremedicineInfection controlbusinessInfluenza and Other Respiratory Viruses
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El tabaquismo pasivo en adultos

2002

Pulmonary and Respiratory Medicinemedicine.medical_specialtyText miningbusiness.industryFamily medicineCase-control studymedicineMEDLINEOdds ratioOccupational exposureProspective cohort studybusinessMeta-Analysis as TopicArchivos de Bronconeumología
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Severe asthma features in children: A case–control online survey

2016

Background Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe. The aim of this study was to provide a detailed characterization of children with severe asthma treated in specialized pediatric asthma centers across Italy. Methods We conducted a web-based data collection of family, environmental, clinical and laboratory characteristics of 41 patients aged 6–17 years with severe asthma, defined according to the recent guidelines of the European Respiratory Society and the American Thoracic Society, and 78 age-matched peers with non-severe persistent asthma. The patients have been enrolled from …

Quality of lifeMalePediatricsmedicine.medical_specialtyAllergyAdolescentmacromolecular substancesSeverity of Illness IndexPediatricsAtopy03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesSeverity of illnessmedicineHumansAsthma; Atopy; Children; Lung function; Quality of life; Pediatrics Perinatology and Child Health030212 general & internal medicineChildChildrenAsthmaRespiratory Function Testbusiness.industryAtopyResearchCase-control studyAsthma; Atopy; Children; Lung function; Quality of life; Adolescent; Asthma; Case-Control Studies; Child; Female; Humans; Italy; Male; Quality of Life; Respiratory Function Tests; Severity of Illness Index; Surveys and Questionnaires; Pediatrics Perinatology and Child HealthOdds ratioAdolescent; Asthma; Case-Control Studies; Child; Female; Humans; Italy; Male; Quality of Life; Respiratory Function Tests; Severity of Illness Index; Surveys and QuestionnairesPerinatology and Child Healthmedicine.diseaseAsthmaLung functionrespiratory tract diseasesRespiratory Function Tests030228 respiratory systemItalyCase-Control StudiesExhaled nitric oxidePediatrics Perinatology and Child HealthFemalebusinessCase-Control StudieHuman
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Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.

2019

Purpose: To evaluate the roles of known myopia-associated genetic variants for development of myopic macular degeneration (MMD) in individuals with high myopia (HM), using case-control studies from the Consortium of Refractive Error and Myopia (CREAM). Methods: A candidate gene approach tested 50 myopia-associated loci for association with HM and MMD, using meta-analyses of case-control studies comprising subjects of European and Asian ancestry aged 30 to 80 years from 10 studies. Fifty loci with the strongest associations with myopia were chosen from a previous published GWAS study. Highly myopic (spherical equivalent [SE] ≤ -5.0 diopters [D]) cases with MMD (N = 348), and two sets of cont…

Refractive errorCandidate genegenetic structuresEmmetropiaGenome-wide association studySensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]Macular DegenerationMathematical and Statistical TechniquesMedicine and Health SciencesMyopiaGeriatric OphthalmologyDioptreVisual ImpairmentsAged 80 and overMultidisciplinaryQRetinal DegenerationStatisticsRGenomicsMetaanalysisPhenotypeResearch DesignPhysical SciencesMedicineRetinal DisordersFemaleAnatomyResearch Articlemedicine.medical_specialtyScienceOcular AnatomySingle-nucleotide polymorphismResearch and Analysis MethodsRetinaOcular SystemOphthalmologyGeneticsGenome-Wide Association StudiesmedicineHumansStatistical Methodsbusiness.industryGene Expression ProfilingCase-control studyBiology and Life SciencesComputational BiologyGenetic VariationCorrectionHuman GeneticsMacular degenerationGenome Analysismedicine.diseaseeye diseasesOphthalmologyGenetic LociGeriatricsMacular DisordersCase-Control StudiesEyessense organsbusinessHeadMathematicsPloS one
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Residential Exposure to PM2.5 Components and Risk of Childhood Non-Hodgkin Lymphoma in Denmark: A Nationwide Register-Based Case-Control Study

2020

In a recent study, we observed an increased risk of childhood non-Hodgkin lymphoma (NHL) associated with exposure to fine atmospheric particulate matter (PM2.5) and black carbon (BC). In this nationwide register-based case-control study, we focus on specific components of PM2.5 in relation to childhood NHL in Denmark (1981&ndash

Register basedMale010504 meteorology & atmospheric sciencesHealth Toxicology and MutagenesisChildhood Non-Hodgkin LymphomaDenmarkSecondary organic aerosolslcsh:Medicine01 natural sciencescomplex mixturesArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineimmune system diseasesInterquartile rangehemic and lymphatic diseasesAir PollutionMedicineHumans030212 general & internal medicineChildsecondary inorganic aerosols0105 earth and related environmental sciencesAerosolsAir Pollutantsparticulate matter componentsSecondary organic aerosolsbusiness.industryLymphoma Non-Hodgkinlcsh:RPublic Health Environmental and Occupational HealthCase-control studyOdds ratiocarbonaceous particlesEnvironmental ExposureConfidence intervalCancer registryregister-based studychemistryCase-Control StudiesParticulate Matterbusinesschildhood Non-Hodgkin LymphomaDemographyEnvironmental MonitoringInternational Journal of Environmental Research and Public Health
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Air pollution exposure at the residence and risk of childhood cancers in Denmark:A nationwide register-based case-control study

2020

Background: The etiology of childhood cancer is poorly understood. The role of environmental factors, including air pollution (AP) exposure, has been addressed previously, but results so far have been inconclusive. In this study, we investigate the association between long-term AP exposures in relation to childhood cancer subtypes in Denmark (1981–2013). Methods: We conducted a nationwide register-based case-control study. We identified 7745 incident cases of childhood cancers (<20 years) in the Danish Cancer Registry. Four randomly selected (cancer-free) controls were matched to each case according to sex and date of birth. We modelled concentrations of nitrogen dioxide (NO2), fine part…

Register basedmedicine.medical_specialtyRegister-based studyAir pollution exposureDenmarkChildhood cancerAir pollution01 natural sciences03 medical and health sciences0302 clinical medicineInternal medicinemedicine030212 general & internal medicine0101 mathematicslcsh:R5-920business.industry010102 general mathematicsCase-control studyGeneral MedicineOdds ratioConfidence intervalEtiologyResidencebusinesslcsh:Medicine (General)Childhood cancerResearch Paper
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Factors explaining being present at work in the forest industry, case–control study

2015

Objectives: The aim of the study was to examine factors explaining few sickness absence hours (=SAH) among forest industry employees. Methods: The source population consisted of 636 forest industry employees in Finland, of which 140 were used as cases (SAH ≤ 1.5% during the past 6.5 years). Controls (140) were randomly selected from the source population (SAH > 1.5%). The study data were collected via a questionnaire. The response rate was 65.4% (mean age 48.5 years, men 67%). Discriminant and log-linear analysis were used to examine the relationships between variables and study groups. Results: Workers are more likely to have few sickness absences when their overall subjective health condi…

Response rate (survey)Sickness absencemedicine.medical_specialtybusiness.industryHealth conditionCase-control studyPhysical Therapy Sports Therapy and RehabilitationMean ageSource PopulationWork (electrical)Physical therapymedicineForest industrybusinessDemographyPhysiotherapy
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Peripheral Frequency of CD4+ CD28- Cells in Acute Ischemic Stroke: Relationship With Stroke Subtype and Severity Markers.

2015

CD4+ CD28− T cells also called CD28 null cells have been reported as increased in the clinical setting of acute coronary syndrome. Only 2 studies previously analyzed peripheral frequency of CD28 null cells in subjects with acute ischemic stroke but, to our knowledge, peripheral frequency of CD28 null cells in each TOAST subtype of ischemic stroke has never been evaluated. We hypothesized that CD4+ cells and, in particular, the CD28 null cell subset could show a different degree of peripheral percentage in subjects with acute ischemic stroke in relation to clinical subtype and severity of ischemic stroke. The aim of our study was to analyze peripheral frequency of CD28 null cells in subjects…

RiskAcute coronary syndromemedicine.medical_specialtySettore MED/09 - Medicina InternaObservational Study5300Severity of Illness IndexArticleBrain IschemiaBrain ischemiaCD28 AntigensInternal medicineSeverity of illnessmedicineNull cellHumanscardiovascular diseasesStrokeAgedbusiness.industryCase-control studyCD28General MedicineFlow Cytometrymedicine.diseaseLymphocyte Subsetsstroke CD4+ CD28-CD4 Lymphocyte CountPeripheralStrokeCardiovascular DiseasesCase-Control StudiesPhysical therapyCardiologybusiness
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