Search results for "Casein"

Determination of milk production losses in Valle del Belice sheep following experimental infection of Mycoplasma agalactiae

2015

Abstract Economic losses due to contagious agalactia (CA) in small ruminant herds are mainly associated with significant reductions in or complete loss of dairy production, mortality, abortions, ill thrift, early culling and costs of control. With the aim of estimating milk production losses caused by CA, 46 primiparous lactating Valle del Belice ewes were monitored after experimental infection. Sixty days after lambing, two ewes were each experimentally infected with a single dose of 10 8  CFU/ml of a live Mycoplasma agalactiae strain in both teats by intracanalicular route. Three days after inoculation, the infection was spread manually by the milkers dipping their hands in the pooled mil…

Influenza del genotipo per l'alfa s1 caseina sulla qualità del latte di capre Maltesi

2010

INTRODUZIONE I numerosi studi sui polimorfismi lattoproteici della capra hanno evidenziato per il gene che codifica per l’alfa (s1)-caseina (CSN1S1) 17 alleli: A, B1, B2, B3, B4, C, D, E, F, G, O1, O2, H, I, L, M, N. Tali alleli sono stati associati a differenti tassi di sintesi di caseina e classificati in quattro gruppi quantitativi: alleli forti (A, B1, B2, B3, B4, C, H, L, M) intermedi (E ed I) e deboli (D, F e G) che sintetizzano rispettivamente un alto (circa 3,5 g/l), medio (circa 1,1 g/l), e basso (0,45 g/l) quantitativo di alfa (s1)-caseina, più alleli nulli (01, 02 e N) che non sintetizzano alfa (s1)-caseina (1, 2). Le varianti genetiche per l’alfa (s1)-caseina influenzano in misu…

Effects of αs1-casein and k- casein genotypes on nutrient intake and milk production in Girgentana goats: a further investigation

2013

The influence of polymorphism at αs1-casein locus (CSN1S1) on goat milk properties is adequately known, whereas the knowl- edge is limited on the effects of κ-casein gene variants (CSN3), C-093 and the association between variants of CSN1S1 and CSN3 Milking technique in jenny: effects on milk production genes. This study aimed to investigate the effect of some CSN1S1-CSN3 composite genotypes (CG) on feed intake and milk production of 95 Girgentana goats from 6 experiments (551 Rossella Di Palo, Diana Neri, Barbara Ariota, Rosanna Serafini, observations). Goats, genotyped using specific PCR protocols at DNA level and IEF technique at milk protein level, were equal at αs2-casein and β-casein …

Effect of CSN1S1 G allele on some characteristics of milk produced by Cinisara cows

2017

In bovine milk about 37-40% of total casein is represented by s1-casein. The CSN1S1 G allele is characterised by a less efficient protein synthesis (about 40%) compared with the other known alleles because of the insertion, in the 19th exon, of a Long Interspersed Nuclear Element relict responsible for a reduced mRNA stability. The lower proportion of s1-casein in milk is associated with faster formation, higher firmness and greater resistance to compression of the curd. The purpose of this study was to analyse the G allele distribution at the CSN1S1 locus in Cinisara breed and its influence on some milk traits. The Cinisara is a small Sicilian breed for which, recently, recovery and safe…

Feed intake, milk composition and cheesemaking properties in Girgentana grazing goats with different genotype at αs1-casein and K-casein

2009

Milk ability for cheese manufacturing depends on both animals utilization of dietary nutrients and genetic polymorphism of caseins. It is well known that strong alleles associated with high content of as1-casein increase cheese-making properties of goat milk, whereas there is little information about effect of genetic variants of κ-casein. The aim of this experiment was to investigate the effect of some composite as1-casein and κ-casein genotypes n changing feeding behavior at pasture and milk yield and properties of Girgentana goats. Forty goats were genotyped at as1, as2, b and κ-casein loci using specific PCR protocols at DNA level and IEF technique at milk protein level. Twelve goats, d…

Effetti della dieta su utilizzazione nutrizionale, risposte metabolico-ormonali, produzione e qualità del latte di capre Girgentane a diversa attitud…

2012

Casein-loaded proteoliposomes: novel delivery strategy to inhibit Aβ1-40 fibrillogenesis in Alzheimer disease

2018

Background: Alzheimer's disease (AD) is a chronic and progressive syndrome, which represents the most common cause of dementia worldwide. A pathological and characteristic AD hallmark is the deposition of amyloid plaques, composed by well-ordered amyloid β-peptide (Aβ) fibers, in brain tissue. The Aβ aggregation process follows typical nucleation-polymerization kinetics, characterized by structural intermediates with specific dimensions, morphologies and cytotoxic activity. Some evidences shifted researchers’ attention to smaller soluble Aβ prefibrillar oligomers as they result the most toxic species. Therefore, novel therapeutic strategies target oligomers or prefibrillar aggregates rather…

Characterization Of Casein-Loaded Proteoliposomes, Potential Inhibitors In Amyloid Fibrillogenesis

Casein-loaded proteoliposomes: Drug Delivery Systems and Potential Inhibitors in Aβ1-40 Fibrillogenesis

2018

Alzheimer's disease (AD) represents the most common cause of dementia worldwide. The early symptom is usually a short-term memory loss, followed by symptoms including problems with language, disorientation, mood swings, loss of motivation, not managing self-care, and behavioral issues, until loss of body functions and, ultimately, death. The cause of AD is poorly understood and the diagnosis is complex. One of the main AD hallmarks is the extracellular deposition in brain tissue of proteinaceous amyloid plaques, composed by well-ordered fibrillary aggregates of the amyloid β-peptide (Aβ). The Aβ aggregation process follows typical nucleation-polymerization kinetics, characterized by structu…

Comparison of Sulla-hay and Sulla-silage in the lactating ewes and their effects on milk and cheese characteristics

2002

Abstract Two methods of storage of Sulla- and oat-grass (silage or hay) were compared. Forty-six homogeneous lactating ewes, housed indoors, were divided into two groups and after 35 days of diet adjustment, were fed ad libitum twice a day, either Sulla- ( Hedysarum coronarium L.) and oat-hay (control group) or Sulla- and oat-silage in partial substitution of hay (silage group). Both groups were fed with 0.5 kg of commercial concentrate. The dietary treatment started 60 days post-lambing and lasted for 58 days. Every day, the feeding intake for each group was recorded. Individual milk yield was measured weekly and at the same time, milk samples were collected and analysed by Milko-Scan 605.…