Search results for "Cataracts"

Refractive changes in nuclear, cortical and posterior subcapsular cataracts. Effect of the type and grade

2015

Purpose: To determine the effect of main morphological types and grades of age-related cataracts on refractive error. Methods: We measured 276 subjects with optical compensation prior to the development of cataract. We evaluated 224 eyes with nuclear cataract, 125 with cortical cataract, and 103 with posterior subcapsular (PSC) cataract classified with LOCSIII. We measured visual acuity (VA) with their spectacles and best-corrected visual acuity (BCVA) with chart in decimal scale to obtain the optimal compensation with cataract. We evaluated the differences between compensations. Results: A significant myopic shift was observed in nuclear cataract from low to mild grade (p = 0.031), the sam…

Axial Elongation following Cataract Surgery during the First Year of Life in the Infant Aphakia Treatment Study

2012

PURPOSE To compare ocular axial elongation in infants after unilateral cataract surgery corrected with a contact lens (CL) or primary intraocular lens (IOL) implantation. METHODS Baseline axial length (AL) was measured at the time of cataract surgery (1-6 months) and at age 1 year. AL at baseline and age 1 year and the change in length/mo were analyzed in relation to treatment modality, cataractous versus fellow eye, and age at surgery using linear mixed models. RESULTS Mean baseline AL did not differ between the CL and IOL groups for either cataractous or fellow eyes. Eyes with cataracts were shorter than fellow eyes by an average of 0.6 mm (95% confidence interval [CI], 0.4-0.8 mm; P < 0.…

The combination of diffractive and refractive multifocal intraocular lenses to provide full visual function after cataract surgery.

2009

PURPOSE To investigate if implantation of a far dominant refractive multifocal intraocular lens (IOL) in one eye and a near dominant diffractive multifocal IOL in the fellow eye improves range of vision following cataract surgery. METHODS This was a prospective, nonrandomized, case-control study involving 20 patients (40 eyes) scheduled for cataract surgery. Inclusion criteria were bilateral cataracts, minimum age 50 years, availability for follow-up visits, and informed consent. All patients received a far dominant refractive multifocal IOL (ReZoom, Abbott Medical Optics) in their dominant eye and a near dominant diffractive multifocal IOL (Tecnis ZM900, AMO) in their nondominant eye. Preo…

Visual outcomes and complications of congenital cataract surgery

2019

Corresponding author at: Department of Ophthalmology, 14, rue Paul-Gaffarel, 21000 Dijon, France. This work is issued from the oral presentation during the 123rd congress of the French Ophthalmological Society.; International audience; PURPOSE: To describe the visual results and postoperative complications of congenital cataract surgeries performed between 2005 and 2016. METHODS: A retrospective consecutive case series of congenital cataract surgeries was carried out at the Dijon University Hospital in France. Intraocular lens implantation was primary or secondary according to age. Pre- and post-operative assessment was performed through ophthalmologic consultations with orthoptic measureme…

Marinesco-Sjögren syndrome caused by a new SIL1 frameshift mutation

2015

no abstract available

The posterior chamber phakic refractive lens (PRL): a review

2012

Implantation of phakic intraocular lenses (pIOLs) is a reversible refractive procedure, preserving the patient’s accommodative function with minimal induction of higher order aberrations compared with corneal photoablative procedures. Despite this, as an intraocular procedure, it has potential risks such as cataracts, chronic uveitis, pupil ovalization, corneal endothelial cell loss, pigmentary dispersion syndrome, pupillary block glaucoma, astigmatism, or endophthalmitis. Currently, only two models of posterior chamber pIOLs are commercially available, the implantable collammer lens (STAAR Surgical Co.) and the phakic refractive lens (PRL; Zeiss Meditec). The number of published reports on…

Presbyopia and the aging eye: Existing refractive approaches and their potential impact on dry eye signs and symptoms.

2020

Every part of the human body is subject to aging, including the eye. Increased prevalence of dry eye disease with age is widely acknowledged: aging threatens ocular surface homeostasis, altering the normal functioning of the lacrimal functional unit and potentially leading to signs and symptoms of dry eye. Parallelly, two additional degenerative processes take place within the crystalline lens, leading to presbyopia and cataractogenesis. With continuously increasing life expectancies both conditions are expected to impact society further. Correction strategies for presbyopia and cataracts either directly or indirectly challenge ocular surface additionally. On one hand, contact lens presbyop…

Pattern Dystrophy of the Macula in a Case of Steinert Disease

2013

&lt;b&gt;&lt;i&gt;Introduction:&lt;/i&gt;&lt;/b&gt; Myotonic dystrophies are typically associated with ocular complications like ptosis, weakness of the ocular muscle and cataracts, but also with less recognized retinal changes. &lt;b&gt;&lt;i&gt;Case Report:&lt;/i&gt;&lt;/b&gt; A 41-year-old female with type 1 myotonic dystrophy complained of progressive vision loss. Slit lamp examination revealed the presence of typical bilateral polychromatic cataract with posterior subcapsular component. Dilated fundus examination was remarkable for bilateral macular depigmented changes. Multimodal imaging analysis of the macula suggested the presence of a butterfly-shaped pattern dystrophy. &lt;b&gt;&l…

The Role of Autophagy in Eye Diseases

2021

Autophagy is a catabolic process that ensures homeostasis in the cells of our organism. It plays a crucial role in protecting eye cells against oxidative damage and external stress factors. Ocular pathologies of high incidence, such as age-related macular degeneration, cataracts, glaucoma, and diabetic retinopathy are of multifactorial origin and are associated with genetic, environmental factors, age, and oxidative stress, among others; the latter factor is one of the most influential in ocular diseases, directly affecting the processes of autophagy activity. Alteration of the normal functioning of autophagy processes can interrupt organelle turnover, leading to the accumulation of cellula…

2015

Ocular signs in Fabry disease have generally been regarded to be primarily of diagnostic value. We explored whether ocular findings, alone or in particular in combination with the α-galactosidase A gene mutation, have predictive value for disease severity. Data from the Fabry Outcome Survey (FOS), a large, global database sponsored by Shire, were selected for adult patients who had undergone ophthalmological examination. Three ocular signs were assessed: cornea verticillata, tortuous conjunctival and/or retinal vessels, and cataract. Fabry disease severity was measured using FOS Mainz Severity Score Index and modifications thereof. Ophthalmological data were available for 1203 (699 female, …