Search results for "Cause"

showing 10 items of 6525 documents

The function of neuromuscular system in maximal stretch-shortening cycle exercises: Comparison between power- and endurance-trained athletes.

1994

Abstract Differences in neuromuscular function between power athletes ( n = 10) and endurance athletes ( n = 10) were investigated in six different experimental conditions. In drop jumps and in stretch-shortening cycle (SSC) exercises on the sledge (sledge jumps), the subjects performed about 10 maximal jumps from the optimum dropping height (O) as well as from the dropping height of optimum −40 cm (O − 40) and optimum +40 cm (O + 40). The five to six best jumps were taken for further analysis. In every condition the power group had better physical performance compared to their endurance counterparts. During the pre-activity, the rate of electromyographic (EMG) development of the power athl…

medicine.medical_specialtybiologyAthletesPower groupBiophysicsNeuroscience (miscellaneous)Concentricbiology.organism_classificationmedicine.disease_causeStretch shortening cyclePower (physics)JumpingPhysical medicine and rehabilitationPhysical performancePhysical therapymedicineEccentricNeurology (clinical)MathematicsJournal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
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Involvement of Different networks in mammary gland involution after the pregnancy/lactation cycle: Implications in breast cancer

2015

Early pregnancy is associated with a reduction in a woman's lifetime risk for breast cancer. However, different studies have demonstrated an increase in breast cancer risk in the years immediately following pregnancy. Early and long-term risk is even higher if the mother age is above 35 years at the time of first parity. The proinflammatory microenvironment within the mammary gland after pregnancy renders an "ideal niche" for oncogenic events. Signaling pathways involved in programmed cell death and tissue remodeling during involution are also activated in breast cancer. Herein, the major signaling pathways involved in mammary gland involution, signal transducer and activator of transcripti…

medicine.medical_specialtybiologyClinical BiochemistryMammary glandCell BiologyTransforming growth factor betamedicine.disease_causemedicine.diseaseBiochemistryChromatin remodelingmedicine.anatomical_structureEndocrinologyBreast cancerInternal medicineGeneticsmedicinebiology.proteinCancer researchInvolution (medicine)Signal transductionCarcinogenesisMolecular BiologyMammary gland involutionIUBMB Life
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SFRR-E Young Investigator AwardeeαB-crystallin modulation after acute exercise in skeletal muscle: the role of oxidative stress and fiber composition.

2015

αB-crystallin (CRYAB) is a member of the small heat shock proteins implicated in various biological functions, particularly in skeletal muscle where it is involved in adaptive remodelling processes, activation of gene transcription and stabilization of nascent proteins.In this research we analysed αB-crystallin' response in mouse gastrocnemius at 15' and 30' of recovery from an acute aerobic exercise (1hour), correlating its modulation with oxidative stress level and fiber composition, red (RG) and white gastrocnemius (WG).We found for the first time that the acute exercise lead to a short term, specific increase of phospho-αB-crystallin level (pCRYAB) in the RG, while no changes were obser…

medicine.medical_specialtybiologySkeletal muscleOxidative phosphorylationmedicine.disease_causeBiochemistryHsp70medicine.anatomical_structureEndocrinologyHsp27BiochemistryCrystallinPhysiology (medical)Internal medicinemedicinebiology.proteinPhosphorylationAerobic exerciseOxidative stressFree radical biologymedicine
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A case report of double etiology of ecthyma gangrenosum

2019

Rationale Ecthyma gangrenosum is a cutaneous infection, most commonly occurring during sepsis evolution with Pseudomonas aeruginosa on an immunocompromised background. There have been rare case reports in previously healthy children and rarer are the cases with double etiology. Patient concerns We present the case of a female Caucasian patient, aged 1 year and 8 months, who developed severe sepsis during flu evolution with predominant respiratory and cerebral manifestations. On admission, at skin level, there was noticed a necrotic coccygeal ulceration (with rapid increasing dimensions 0.5/0.5 cm in 24 hours), and with the transformation from a dry necrosis in a sphacelus at the periphery a…

medicine.medical_specialtybiologybusiness.industryTeicoplaninPseudomonas aeruginosaGeneral Medicinemedicine.diseasemedicine.disease_causebiology.organism_classificationDermatologyEnterococcus faecalisSepsisEcthyma gangrenosum03 medical and health scienceschemistry.chemical_compound0302 clinical medicinechemistryAmikacin030220 oncology & carcinogenesisLinezolidEtiologyMedicine030212 general & internal medicinebusinessmedicine.drugMedicine
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PO-0779 Which Parameters Are Mandatory In Urinary Tract Infection In Children?

2014

Background The protocol of investigations in urinary tract infection (UTI) in children mandatory includes urianalysis, uroculture, reactive C protein (RCP), blood urea (BUN), renal ultrasonography and scintigraphy. Each one of these has limits to perform in children. Aims To establish the correlations between UTI investigations for argumentation the therapeutic decision. Methods Retrospective study of hospitalised paediatric patients for UTI. The study parameters were: age, symptoms, RCP, BUN, uroculture, renal ultrasonography, urinanalysis (leukocytes, nitrites, pH, density, proteins, erythrocytes, ascorbic acid-AA). Results Were studied 243 hospitalised and treated with antibiotics UTI. U…

medicine.medical_specialtybiologymedicine.diagnostic_testbusiness.industrymedicine.drug_classUrinary systemAntibioticsRetrospective cohort studyGuidelineurologic and male genital diseasesbiology.organism_classificationScintigraphymedicine.disease_causefemale genital diseases and pregnancy complicationsSurgeryProteusEnterococcusInternal medicinePediatrics Perinatology and Child HealthMedicinebusinessStaphylococcusArchives of Disease in Childhood
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Bloodstream infections in intensive care unit patients: Distribution and antibiotic resistance of bacteria

2015

Vincenzo Russotto,1 Andrea Cortegiani,1 Giorgio Graziano,2 Laura Saporito,2 Santi Maurizio Raineri,1 Caterina Mammina,2 Antonino Giarratano1 1Department of Biopathology and Medical Biotechnologies (DIBIMED), Section of Anaesthesia, Analgesia, Intensive Care and Emergency, Paolo Giaccone University Hospital, University of Palermo, Palermo, Italy; 2Department of Sciences for Health Promotion and Mother-Child Care, University of Palermo, Palermo, Italy Abstract: Bloodstream infections (BSIs) are among the leading infections in critically ill patients. The case-fatality rate associated with BSIs in patients admitted to intensive care units (ICUs) reaches 35%–50%. The emergence and diffusi…

medicine.medical_specialtybloodstream infectionsmedicine.drug_classAntibioticsICU; MDR; antibiotic; bloodstream infections; intensive care unit; multidrug resistantSettore MED/41 - AnestesiologiaReviewBloodstream infectionmedicine.disease_causelcsh:Infectious and parasitic diseaseslaw.inventionAntibiotic resistancelawIntensive careEpidemiologyMDRmedicinelcsh:RC109-216Pharmacology (medical)Intensive care unitMED/41 - ANESTESIOLOGIAIntensive care medicinePharmacologybiologybusiness.industryAntibioticAcinetobacterbiology.organism_classificationIntensive care unitMultiple drug resistanceInfectious DiseasesMultidrug resistantStaphylococcus aureusICUAntibiotic; Bloodstream infections; ICU; Intensive care unit; MDR; Multidrug resistantbusiness
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Interrelationships between oxidative stress and MMP-9 in subjects with severe obstructive sleep apnea syndrome

2016

Obstructive sleep apnea syndrome (OSAS) is significantly and independently associated with an increased risk of cardiovascular diseases, cerebrovascular events and all-cause mortality and some studies have demonstrated that the incidence of cardiovascular events is related to its severity. Our aim was to examine the oxidative status and the matrix metalloproteases (MMP) profile in a group of subjects with OSAS. We enrolled 48 subjects with OSAS, defined after a 1-night cardiorespiratory sleep study, which were subsequently subdivided in two subgroups according to the severity of OSAS: mild-moderate OSAS = “Low”, severe OSAS = “High”. We measured the parameters of oxidative stress, such as l…

medicine.medical_specialtybusiness.industryCardiorespiratory fitnessmedicine.disease_causemedicine.diseaseProtein oxidationLipid peroxidationObstructive sleep apneachemistry.chemical_compoundEndocrinologychemistryInternal medicinemedicineTBARSSleep studyEndothelial dysfunctionbusinessOxidative stress4.2 Sleep and Control of Breathing
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A case of Fitz Hugh Curtis syndrome mimicking an acute abdomen

2021

Fitz Hugh Curtis syndrome, also known as acute perihepatitis, associates pelvic inflammatory disease with the presence of Chlamydia trachomatis or Neisseria gonorrhoeae as the main causative pathogens.
 Symptomatology is a nonspecific one. Right upper quadrant pain, fever, nausea and vomiting are the most commonly encountered symptoms.
 Imaging data are also nonspecific and often show intra-abdominal changes with no particularity.
 As it is difficult to suspect Fitz Hugh Curtis syndrome upon first impression, laparoscopy and direct visualization of the peritoneum and liver adhesions are needed in the diagnostic process. The specific aspect of the fibrinous strands can raise t…

medicine.medical_specialtybusiness.industryCase ReportGeneral Medicinemedicine.diseasemedicine.disease_causeGastroenterologyFitz-Hugh–Curtis syndromePerihepatitisAcute abdomenInternal medicinePelvic inflammatory diseasemedicinemedicine.symptomChlamydia trachomatisbusinessMedicine and Pharmacy Reports
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<tocheading>Original Article</tocheading>

1999

In this double-blind clinical trial 429 patients (217 terbinafine and 212 clotrimazole) were randomized to receive twice daily terbinafine 1% topical solution for 1 week followed by a vehicle application for 3 weeks, or 1% clotrimazole solution for 4 weeks. Patients were evaluated clinically and mycologically at baseline and then at weeks one, two, four (end of treatment), and eight (end of follow-up). To be evaluable the patient needed to have a positive culture for a dermatophyte and positive KOH microscopy and a clinical diagnosis of tinea pedis (interdigital type) at baseline. Effective treatment of tinea pedis was recorded in 181 of 217 (83%) of patients treated for 1 week with terbina…

medicine.medical_specialtybusiness.industryClotrimazoleDermatologyGeneral Medicinemedicine.disease_causemedicine.diseaseDermatologylaw.inventionClinical trialInfectious DiseasesRandomized controlled trialTolerabilitylawmedicineDermatophyteTerbinafinebusinessAdverse effectMycosismedicine.drugMycoses
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The Relationship between an Oxidative Stress Biomarker and Plasma Haemoglobin in Patients with Chronic Kidney Disease

2010

Introduction: Evidence suggests that decreased haemoglobin plasma concentration may be a predictor of adverse cardiovascular events in patients with chronic kidney disease (CKD). We hypothesized that in CKD patients, oxidative stress could influence the development of cardiovascular damage via a relationship with haemoglobin levels. Methods: We assayed plasma levels of the biomarker of oxidative stress 8-ISO-prostaglandin F2α (8-ISO-PGF2α) and of haemoglobin in 193 stage 2–5 CKD patients, investigating their relationship. Eighty healthy subjects and 80 patients with primary hypertension having normal renal function were enrolled as controls. Results: The CKD group was divided according to 8…

medicine.medical_specialtybusiness.industryConfoundingRenal functionAnaemiaHaemoglobins generalmedicine.diseasemedicine.disease_causeNitric oxideKidney-disorderschemistry.chemical_compoundEndocrinologychemistryStatistical significanceInternal medicineInternal MedicinemedicineBiomarker (medicine)Kidney disorderCardiology and Cardiovascular MedicinebusinessOxidative stressKidney diseaseHigh Blood Pressure & Cardiovascular Prevention
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