Search results for "Cave"

showing 10 items of 606 documents

Prefacio: Lost in the Stars

2020

SI tratta della prefazione a: J.J. Moreso, Lo normativo: variedades y variaciones, ISBN 978-84-259-1855-1, Centro de Estudios Politícos y Constitucionales, Madrid 2020

Settore IUS/20 - Filosofia Del DirittoPlatone caverna (mito della)ordinamento giuridico
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The beginning of the Neolithic in Southern Italy and Sicily

2018

Abstract The process of Neolithization of Southern Italy and Sicily covers about 500 years (6200–5700 cal BC) and involves two cultural horizons: Archaic Impressed Ware or “Impresse Arcaiche” and Advanced Impressed Ware or “Impresse Evolute”. In Southern Italy the Neolithic peopling from the East is characterized by a “package” of plenty domesticated plants and livestock; in Sicily the adoption of the new economical system is apparently more slow and with no evidences of ruptures between the Mesolithic groups and first farmers. In this paper we present the chronological and cultural framework of the sixth millennium BC within the area of investigation, with an up-to-date bibliography about …

Settore L-ANT/01 - Preistoria E Protostoria010506 paleontologyClimate01 natural sciencesCave0601 history and archaeologyNeolithicDomesticationSicilyShort durationMesolithic0105 earth and related environmental sciencesEarth-Surface ProcessesOpen airShoregeographygeography.geographical_feature_category060102 archaeologybusiness.industrySettore L-ANT/09 - Topografia Anticasettlement strategie06 humanities and the artsArchaeologyLivestockSouthern ItalybusinessSettlement (litigation)MesolithicQuaternary International
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Petrographic characterization of quartzite tools from the Palaeolithic site of San Teodoro cave (Sicily): Study on the provenance of lithic raw mater…

2022

A petrographic characterization has been used here, for the first time, in the study of lithic raw materials exploited in prehistoric Sicily. Our research interests one of the oldest archaeological sites with evidence of the early human peopling of the island (∼15kyr ago): San Teodoro Cave, in northeastern Sicily. Two geological Formations, Numidian and Monte Soro Flysch gave origin to well-rounded pebbly quartzite elements scattered in the marine terraces surrounding the cave and likely exploited as one of the sources of the raw materials for the production of lithic tools by the Epigravettian communities having settled the place. The preference for one of the two qualities of quartzite is…

Settore L-ANT/01 - Preistoria E ProtostoriaArcheologyLithic artefacts Quartzite Epigravettian Palaeolithic San Teodoro CaveSettore L-ANT/09 - Topografia AnticaSettore GEO/01 - Paleontologia E PaleoecologiaSettore BIO/08 - AntropologiaSettore GEO/09 -Georis. Miner.e Appl.Mineral.-Petrogr. per l'Ambi.ed i B.Cult.Journal of Archaeological Science: Reports
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Within the symbolic world of the prehistoric hunters: A GIS-based and 3D model analysis of sites with complexes of linear incisions in western Sicily

2021

Abstract The prehistoric peopling of Sicily has left scattered traces of symbolic activities through well-known rock art expressions in caves and rock shelters located all around the island (among the most significant, the sites of Addaura, Racchio and Genovese). A peculiar phenomenon is the incision of linear signs, often grouped on the same rocky walls, hidden in fissures or placed at the entrance of the underground chambers of caves. In this report, we investigate a sample of these graphic expressions from a spatial and technical point of view. A GIS-based approach presents the territorial pattern providing insight, on a macroscale, into the intentional positioning of the sign complexes.…

Settore L-ANT/01 - Preistoria E ProtostoriaArcheologygeographygeography.geographical_feature_category060102 archaeology010401 analytical chemistrySign (semiotics)3d modelSettore L-ANT/09 - Topografia Antica06 humanities and the artsSettore BIO/08 - Antropologia01 natural sciencesArchaeology0104 chemical sciencesComputer Science ApplicationsPrehistoryCaveAnthropology3D models Rock art Spatial analysis Symbols Anthropology Prehistory0601 history and archaeologyThe SymbolicRock art
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Immaginazione

2022

The most recent discoveries deriving from the exchanges between aesthetics and neuroscience – especially those stressing the importance of the sensory-motor system in both scientific and aesthetic experience – have raised a particular attention on the subjectivity of mental processes, especially those related to the knowledge processes, and on the role of imagination. These results have, still nowadays, influence and confirmation in literature, which many scholars interested in a cognitivistic approach consider as related, if not just the same, to the ability of mankind to make tools and, thus, to make sense. An example of this reciprocal influence of neuroscience and literature is without …

Settore L-FIL-LET/14 - Critica Letteraria E Letterature ComparateSiri Hustvedt Margaret Cavendish experimental philosophy neuroaesthetics masquerade.
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Il fondamento estetico del pensiero di Stanley Cavell.

2011

Settore M-FIL/04 - Esteticapensiero di Stanley Cavell.fondamento estetico
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Multiple solutions with sign information for a (p,2)-equation with combined nonlinearities

2020

We consider a parametric nonlinear Dirichlet problem driven by the sum of a p-Laplacian and of a Laplacian (a (p,2)-equation) and with a reaction which has the competing effects of two distinct nonlinearities. A parametric term which is (p−1)-superlinear (convex term) and a perturbation which is (p−1)-sublinear (concave term). First we show that for all small values of the parameter the problem has at least five nontrivial smooth solutions, all with sign information. Then by strengthening the regularity of the two nonlinearities we produce two more nodal solutions, for a total of seven nontrivial smooth solutions all with sign informations. Our proofs use critical point theory, critical gro…

Settore MAT/05 - Analisi MatematicaConstant sign and nodal solutionFlow invarianceConvex–concave problemStrong comparison principleCritical groupNonlinear regularity
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Lipid and apoprotein composition of HDL in partial or complete CETP deficiency

2012

Hyperalphalipoproteinemia, as observed in patients who are either homozygous or heterozygous for cholesteryl ester transfer protein (CETP) deficiency, has been shown to be associated with striking changes in apolipoprotein size distribution, namely, of high-density lipoprotein (HDL) and HDL-like particles. We compared the effect of varying degrees of CETP activity on the HDL apolipoprotein profile in Caucasian CETP-deficient subjects and following pharmacological decrease in CETP activity, using Size Exclusion Chromatography followed by Reverse Phase Protein Array (SEC RPA). The main HDL-associated apolipoproteins (Apo), i.e. ApoA-I, ApoA-II, ApoC-I, and ApoC-III, co-eluted with the HDL pea…

Settore MED/09 - Medicina InternaApolipoprotein BCholesterol Ester Transfer Proteinmedicine.disease_causereverse phase protein arraychemistry.chemical_compoundExonMutationbiologyHomozygotescavenger receptor class B1size exclusion chromatographyLipidCholesteryl ester transfer proteinLipidstorcetrapibApolipoproteinBiochemistryELISAlipids (amino acids peptides and proteins)hyperalphalipoproteinemiaCardiology and Cardiovascular MedicineLipoproteins HDLHumandalcetrapibmedicine.medical_specialtyHeterozygoteDalcetrapibHypercholesterolemiaapolipoproteinhigh-density lipoproteinInternal medicineCholesterylester transfer proteinmedicineAnimalsHumansCholesteryl ester transfer protein; dalcetrapib; high-density lipoprotein; reverse phase protein array; scavenger receptor class B1; size exclusion chromatography; torcetrapib; apolipoprotein; hyperalphalipoproteinemia; ELISAPharmacologybusiness.industryAnimalPoint mutationCholesterol HDLTorcetrapibnutritional and metabolic diseasesLipid MetabolismCholesterol Ester Transfer Proteinscarbohydrates (lipids)Disease Models AnimalEndocrinologyApolipoproteinschemistrybiology.proteinbusinessLipoprotein
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Developing drug strategies for the neuroprotective treatment of acute ischemic stroke

2015

Developing new treatment strategies for acute ischemic stroke in the last twenty years has offered some important successes, but also several failures. Most trials of neuroprotective therapies have been uniformly negative to date. Recent research has reported how excitatory amino acids act as the major excitatory neurotransmitters in the cerebral cortex and hippocampus. Furthermore, other therapeutic targets such as free radical scavenger strategies and the anti-inflammatory neuroprotective strategy have been evaluated with conflicting data in animal models and human subjects with acute ischemic stroke. Whereas promising combinations of neuroprotection and neurorecovery, such as citicoline,…

Settore MED/09 - Medicina InternaBioinformaticsNeuroprotectionlaw.inventionBrain ischemiachemistry.chemical_compoundRandomized controlled triallawAnimalsHumansMedicinePharmacology (medical)Strokebusiness.industryGeneral NeurosciencedrugIschemic cascadeFree radical scavengermedicine.diseaseStrokeNeuroprotective AgentschemistryCerebrolysinneuroprotectionNeurology (clinical)businessNeuroscienceCiticolinemedicine.drugExpert Review of Neurotherapeutics
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eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency.

2014

Mutations in the CETP gene resulting in defective CETP activity have been shown to cause remarkable elevations of plasma HDL-C levels, with the accumulation in plasma of large, buoyant HDL particles enriched in apolipoprotein E. Genetic CETP deficiency thus represents a unique tool to evaluate how structural alterations of HDL impact on HDL atheroprotective functions. Aim of the present study was to assess the ability of HDL obtained from CETP-deficient subjects to protect endothelial cells from the development of endothelial dysfunction. HDL isolated from one homozygous and seven heterozygous carriers of CETP null mutations were evaluated for their ability to down-regulate cytokine-induced…

Settore MED/09 - Medicina InternaCHOLESTEROL EFFLUXApolipoprotein BEpidemiologylcsh:MedicineANTIINFLAMMATORY PROPERTIESmedicine.disease_causeBiochemistryVascular Medicinechemistry.chemical_compoundHigh-density lipoproteinEnosMedicine and Health SciencesEndothelial dysfunctionlcsh:ScienceMutationMultidisciplinarybiologyHomozygoteCETP; eNOS; HDL;NeurochemistryLipidsGenetic EpidemiologyeNOSlipids (amino acids peptides and proteins)AnatomyNeurochemicalsLipoproteins HDLResearch Articlemedicine.medical_specialtyDrug Research and DevelopmentHDLNitric Oxide Synthase Type IIILipoproteinsENDOTHELIAL FUNCTIONINHIBITIONCardiologyDown-RegulationVascular Cell Adhesion Molecule-1Nitric OxideCELL-ADHESION MOLECULE-1Lipid Metabolism Inborn ErrorsESTER TRANSFER PROTEINInternal medicineCETPCholesterylester transfer proteinHuman Umbilical Vein Endothelial CellsmedicineHumansNITRIC-OXIDE SYNTHASEInflammationClinical GeneticsPharmacologyCholesterollcsh:RTorcetrapibEndothelial CellsBiology and Life SciencesProteinsnutritional and metabolic diseasesLipid MetabolismAtherosclerosismedicine.diseasebiology.organism_classificationCholesterol Ester Transfer Proteinscarbohydrates (lipids)MetabolismEndocrinologychemistryOther Clinical MedicineMutationImmunologyCardiovascular Anatomybiology.proteinlcsh:QTORCETRAPIBClinical MedicineHIGH-DENSITY-LIPOPROTEINSCAVENGER RECEPTOR BI
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