Search results for "Celastraceae"

showing 3 items of 3 documents

Environmental and Biochemical Factors Controlling the in Vitro Emergence of Somatic Embryos in European Spindle Tree (Euonymus europaeus L)

2000

The European spindle tree (Euonymus europaeus L. Celastraceae) is a shrubby tree widely distributed in temperate regions of western European countries from the northern part of France to St. Petersburg and the western part of Russia. The Celastraceae comprises 55 genera, including at least 850 known species of trees and shrubs which are found in tropical and temperate regions. Various secondary metabolites are elaborated in the family including steroids, triterpenoids, sesquiterpene, peptide ore alkaloids. The spindle tree is commonly found in quickset hedges and small broad-leaved forests when the soil is deep, moist, clayey and chalky. The leaves are relatively small (3–4 cm long) simple …

CelastraceaeTriterpenoidSomatic embryogenesisbiologyEcotypevisual_artBotanyvisual_art.visual_art_mediumTemperate climateEuropean Spindle-TreeBarkEuonymus europaeusbiology.organism_classification
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Antinociceptive effects of an extract, fraction and an isolated compound of the stem bark of Maytenus rigida

2012

The antinociceptive activity of the Maytenus rigida Mart. (Celastraceae) ethanol extract and its ethyl acetate fraction as well as of (-)-4'-methylepigallocatechin (1), a previously isolated compound, was demonstrated in vivo. ED50 for 1 in the writhing test was 14.14 mg/kg. The acetic acid-induced writhing was inhibited by 98.4, 84.4, and 58.3%, respectively, when mice were treated with the ethanol extract, ethyl acetate fraction, and 1. In the hot plate test, mice pretreated with 1 showed significantly increased reaction times (60-89%). Oral administration of 1 significantly inhibited first and second phases of the formalin-induced pain (50 and 26.5%, respectively), whereas indomethacin i…

EthanolbiologyStereochemistryChemistry(-)-4'-methylepigallocatechinAnalgesicEthyl acetatelcsh:RS1-441PharmacologyCelastraceaebiology.organism_classificationCelastraceaelcsh:Pharmacy and materia medicachemistry.chemical_compoundantinociceptive activityMaytenus rigidaOral administrationIn vivoGeneral Pharmacology Toxicology and PharmaceuticsHot plate testanti-inflammatory activityED50Revista Brasileira de Farmacognosia
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Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2

2005

In the present study, we report that three new lupane triterpenes (1-3), in addition to 16 known ones (4-19), were isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis. Their structures were elucidated by spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC, and HMBC). The natural compounds and derivatives 6a, 6b, 9a, and 9b have been tested for potential anti-inflammatory activity, and several compounds including 3-epicalenduladiol (2), 11alpha-hydroxy-glochidone (3), rigidenol (6), acetoxy-rigidenol (6a), 11alpha-acetoxy-30-chloro-3-oxo-lup-20(29)-ene (6b), betulin (9), 28-acetoxy-betulin (9a), epibetul…

StereochemistryClinical BiochemistryPharmaceutical SciencePharmacognosyNitric OxideBiochemistryDinoprostoneTerpeneCelastraceaeMiceStructure-Activity Relationshipchemistry.chemical_compoundTriterpeneDrug DiscoveryAnimalsMolecular Biologychemistry.chemical_classificationBetulinbiologyMaytenusMacrophagesSpectrum AnalysisOrganic ChemistryBiological activityBacterial InfectionsMaytenusbiology.organism_classificationAntineoplastic Agents PhytogenicTriterpenesTerpenoidEndotoxinsPlant LeaveschemistryMolecular MedicineBioorganic & Medicinal Chemistry
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