Search results for "Cement"

showing 10 items of 2662 documents

Value of texture analysis on gadoxetic acid–enhanced MRI for differentiating hepatocellular adenoma from focal nodular hyperplasia

2019

OBJECTIVE. The objective of our study was to assess the diagnostic performance of texture analysis (TA) on gadoxetic acid-enhanced MR images for differentiation of hepatocellular adenoma (HCA) from focal nodular hyperplasia (FNH).MATERIALS AND METHODS. This study included 40 patients (39 women and one man) with 51 HCAs and 28 patients (27 women and one man) with 32 FNH lesions. All lesions were histologically proven with preoperative MRI performed with gadoxetic acid. Two readers reviewed all the imaging sequences to assess the qualitative MRI characteristics. The T2-weighted fast spin-echo, hepatic arterial phase (HAP), and hepatobiliary phase (HBP) sequences were used for TA. Textural fea…

AdultGadolinium DTPAMaleGadoxetic acidCarcinoma Hepatocellulargenetic structuresAdolescenthepatocellular adenomaContrast MediaSensitivity and Specificity030218 nuclear medicine & medical imagingAdenoma Liver CellDiagnosis Differential03 medical and health sciences0302 clinical medicineImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imagingTexture (crystalline)Agedfocal nodular hyperplasiabusiness.industryLiver NeoplasmsFocal nodular hyperplasiatexture analysiGeneral MedicineHepatocellular adenomaMiddle Agedmedicine.diseaseImage EnhancementMagnetic Resonance Imagingdigestive system diseases030220 oncology & carcinogenesisFemaleMr imagesNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaValue (mathematics)medicine.drugMRI
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Gadoxetic acid-enhanced MRI of transient hepatic enhancement differences: Another cause of hypointense observation on hepatobiliary phase

2018

Purpose: To retrospectively determine the frequency, natural history and factors associated with the presence of transient hepatic enhancement difference showing hypointensity on hepatobiliary phase images of gadoxetic acid-enhanced MRI. Materials and methods: Gadoxetic acid-enhanced MRI of 125 patients (91 men; 34 women) with transient hepatic enhancement difference were retrospectively reviewed. Three readers qualitatively and quantitatively evaluated MR imaging features and evolution at follow up. The Chi-square test, Fisher's exact test and Kruskall-Wallis rank test were used for statistical analysis. Results: Transient hepatic enhancement difference were hypointense on hepatobiliary ph…

AdultGadolinium DTPAMaleGadoxetic acidGadoxetic acidContrast MediaAbdomen/GI030218 nuclear medicine & medical imagingHemodynamics/flow dynamic03 medical and health sciences0302 clinical medicineImage Processing Computer-AssistedHumansMedicineRadiology Nuclear Medicine and imagingStatistical analysisAgedRetrospective StudiesAged 80 and overUnivariate analysisbusiness.industryLiver DiseasesGeneral MedicineMiddle AgedImage EnhancementMagnetic Resonance ImagingMr imagingHyperintensityMR-imagingExact testLiver030220 oncology & carcinogenesisMultivariate AnalysisHepatocytesHepatobiliary phaseFemalebusinessNuclear medicinemedicine.drugEuropean Journal of Radiology
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Preliminary experience with the application of Gadolinium-DTPA before MR imaging-guided laser-induced interstitial thermotherapy of brain tumors

1997

The purpose of this study was to investigate the potential value of i.v. gadolinium-diethylenetriamine penta-acetic acid (Gd-DTPA) applied before MRI-guided laser-induced interstitial thermotherapy (LITT) of brain tumors without original enhancement, especially in defining total lesion size during therapy. MRI-guided LITT was performed on two patients with astrocytoma WHO II. For both patients, Gd-DTPA was administered intravenously after a first irradiation period and LITT was continued after pulling back the light guide to coagulate the upper parts of the tumor. In both patients, the whole irreversible damaged zone of the second irradiation period after Gd-DTPA showed an intense increase …

AdultGadolinium DTPAMalePathologymedicine.medical_specialtySpatial expansionGadoliniumchemistry.chemical_elementAstrocytomaDrug Administration ScheduleLesionGadolinium DTPAOrganometallic CompoundsmedicineHumansRadiology Nuclear Medicine and imagingBrain Neoplasmsbusiness.industryAstrocytomaLight guideHyperthermia InducedPentetic AcidImage Enhancementmedicine.diseaseMagnetic Resonance ImagingMr imagingchemistryFemaleLaser TherapySignal intensitymedicine.symptomNuclear medicinebusinessFollow-Up StudiesJournal of Magnetic Resonance Imaging
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Assessment of tumor microcirculation with dynamic contrast-enhanced MRI in patients with esophageal cancer: initial experience.

2008

PURPOSE: To investigate the feasibility and impact of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) on tumor characterization and response to radiochemotherapy (RCT) in patients with esophageal cancer. MATERIALS AND METHODS: A total of 48 patients underwent DCE-MRI to assess tumor microcirculation based on a two-compartment model function. Effects of RCT on kinetic parameters were studied in 12 patients with squamous cell carcinoma. RESULTS: Tumor microcirculation differs with respect to histological subtype: squamous cell carcinomas showed lower values of amplitude A (leakage space, P = 0.015) and higher contrast agent exchange rates (k(21), P = 0.225) compared with adenoc…

AdultGadolinium DTPAMalemedicine.medical_specialtyEsophageal NeoplasmsUrologyContrast MediaAdenocarcinomaMicrocirculationlaw.inventionRandomized controlled triallawmedicineCarcinomaImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingAgedObserver Variationmedicine.diagnostic_testbusiness.industryMicrocirculationTherapeutic effectMagnetic resonance imagingEsophageal cancerMiddle Agedmedicine.diseaseImage EnhancementMagnetic Resonance ImagingTreatment OutcomeDynamic contrast-enhanced MRICarcinoma Squamous CellFeasibility StudiesHistopathologyFemaleRadiologybusinessJournal of magnetic resonance imaging : JMRI
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Chronic Thromboembolic Pulmonary Hypertension: Pre- and Postoperative Assessment with Breath-hold MR Imaging Techniques

2004

To evaluate the potential of breath-hold magnetic resonance (MR) imaging techniques in morphologic and functional assessment of patients with chronic thromboembolic pulmonary hypertension (CTEPH) before and after surgery.Thirty-four patients with CTEPH were examined before and after pulmonary thromboendarterectomy (PTE). For morphologic assessment, contrast material-enhanced MR angiography was used; for assessment of hemodynamics, velocity-encoded gradient-echo sequences and cine gradient-echo sequences along the short axis of the heart were performed. Contrast-enhanced MR angiography was compared with selective digital subtraction angiography (DSA) for depiction of central thromboembolic m…

AdultGadolinium DTPAMalemedicine.medical_specialtyHypertension Pulmonarymedicine.medical_treatmentContrast MediaMagnetic Resonance Imaging CineEndarterectomyPulmonary ArterySensitivity and SpecificityVentricular Function LeftMagnetic resonance angiographyPostoperative ComplicationsHeart SeptumImage Processing Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesAgedThrombectomyEndarterectomymedicine.diagnostic_testPulmonary thromboendarterectomybusiness.industryHemodynamicsAngiography Digital SubtractionMagnetic resonance imagingDigital subtraction angiographyMiddle AgedImage Enhancementmedicine.diseaseMagnetic Resonance ImagingPulmonary hypertensionmedicine.anatomical_structureChronic DiseaseAngiographyVentricular Function RightFemaleRadiologyPulmonary EmbolismbusinessBlood Flow VelocityMagnetic Resonance AngiographyFollow-Up StudiesArteryRadiology
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Kardiale MRT : Änderungen der normalisierten myokardialen Gadolinium-Anreicherung über die Zeit nach Kontrastmittelinjektion in Patienten mit akuter …

2011

PURPOSE An increased normalized gadolinium accumulation (NGA) in the myocardium during early washout has been used for the diagnosis of acute myocarditis (AM). Due to the fact that the pharmacokinetics of contrast agents are complex, time-related changes in NGA after contrast injection are likely. Because knowledge about time-related changes of NGA may improve the diagnostic accuracy of MR, our study aimed to estimate the time course of NGA after contrast injection in patients as well as in healthy volunteers. MATERIALS AND METHODS An ECG-triggered inversion recovery SSFP sequence with incrementally increasing inversion times was repetitively acquired over the 15 minutes after injection of …

AdultGadolinium DTPAMalemedicine.medical_specialtymedia_common.quotation_subjectGadoliniumCardiac-Gated Imaging TechniquesMedizinchemistry.chemical_elementContrast MediaSensitivity and SpecificityPharmacokineticsReference ValuesInternal medicineHealthy volunteersmedicineImage Processing Computer-AssistedContrast (vision)HumansRadiology Nuclear Medicine and imagingIn patientMuscle Skeletalmedia_commonbusiness.industryMyocardiumWashoutSteady-state free precession imagingMiddle AgedImage EnhancementMagnetic Resonance ImagingMyocardial ContractionMyocarditischemistryContrast injectionAcute DiseaseInjections IntravenousCardiologyFemalebusiness
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Magnetically labeled water perfusion imaging of the uterine arteries and of normal and malignant cervical tissue: initial experiences.

1998

Purpose: The aim of this pilot study was to evaluate a magnetically labeled water perfusion imaging technique as a non-contrast-enhanced approach to demonstrate the uterine artery, its branches, and to assess the cervical uterine blood flow in healthy volunteers and in patients with advanced uterine cervical carcinoma (FIGO IIB-IVA). Methods and Materials: Seven healthy volunteers (mean age, 29 years) and twenty-two patients (mean age, 52 years) with advanced cancer of the uterine cervix (FIGO IIB-IVA) were prospectively examined by magnetically labeled water perfusion imaging at different inversion delay times (300–900 ms). The magnetic resonance imaging (MRI) findings of all patients were…

AdultGadolinium DTPAPathologymedicine.medical_specialtyBiomedical EngineeringBiophysicsHemodynamicsContrast MediaUterine Cervical NeoplasmsPerfusion scanningCervix UteriSensitivity and Specificitymedicine.arterymedicineHumansRadiology Nuclear Medicine and imagingUterine arteryCervixAgedNeoplasm Stagingmedicine.diagnostic_testNeovascularization Pathologicbusiness.industryUterusHemodynamicsWaterMagnetic resonance imagingBlood flowArteriesMiddle AgedImage EnhancementMagnetic Resonance ImagingPerfusionmedicine.anatomical_structureDynamic contrast-enhanced MRIFemaleNuclear medicinebusinessPerfusionBlood Flow VelocityMagnetic resonance imaging
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Cardiac Magnetic Resonance with Delayed Enhancement of the Right Ventricle in patients with Left Ventricle primary involvement: diagnosis and evaluat…

2020

: Cardiac Magnetic Resonance (CMR) allows an accurate Right Ventricle (RV) assessment that could be of great relevance in diseases causing inflammation or fibrosis. The aim of this study was to evaluate the concomitant involvement of the RV in patients with delayed enhancement (DE) of the Left Ventricle (LV-DE) using CMR. We retrospectively enrolled 95 (male n. 66; age 55±18years; BMI 26±5kg/m2) consecutive patients with LV-DE who underwent a CMR (Achieva 1.5 T, Philips) for different indications: post-ischemic dilated cardiopathy (PDM), hypertrophic cardiomyopathy (HCM), myocardial infarction (MI), myocarditis/pericarditis (MP) and congenital heart disease (CD). We assessed the presence an…

AdultHeart Defects CongenitalMaleMagnetic Resonance SpectroscopyHeart VentriclesStroke VolumeMiddle AgedDelayed EnhancementMagnetic Resonance ImagingRight VentricleHumansCardiac Magnetic ResonanceCardiomyopathiesSettore MED/36 - Diagnostica Per Immagini E RadioterapiaLeft VentricleAgedRetrospective StudiesActa bio-medica : Atenei Parmensis
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AISF update on the diagnosis and management of adult-onset lysosomal storage diseases with hepatic involvement.

2020

Lysosomal storage diseases (LSDs) are a heterogeneous group of inherited disorders caused by loss-of-function mutations in genes encoding for lysosomal enzymes/proteins. The consequence is a progressive accumulation of substrates in these intracellular organelles, resulting in cellular and tissue damage. The overall incidence is about 1/8000 live births, but is likely underestimated. LSDs are chronic progressive multi-systemic disorders, generally presenting with visceromegaly, and involvement of the central nervous system, eyes, the skeleton, and the respiratory and cardiovascular systems. The age at onset and phenotypic expression are highly variable, according to the specific enzymatic d…

AdultHepatosplenomegalyLysosomal acid lipase deficiencyBioinformaticsOrganomegaly03 medical and health sciencesLiver disease0302 clinical medicinemedicineCholesteryl ester storage disease Enzyme replacement therapy Gaucher disease Lysosomal acid lipase Niemann–Pick disease deficiency Substrate reduction therapyHumansSubstrate reduction therapyEnzyme Replacement TherapySocieties MedicalNiemann-Pick DiseasesAcid sphingomyelinase deficiencyGaucher DiseaseHepatologybusiness.industryGastroenterologyWolman DiseaseEnzyme replacement therapymedicine.diseaseLysosomal Storage DiseasesSphingomyelin PhosphodiesteraseItaly030220 oncology & carcinogenesis030211 gastroenterology & hepatologymedicine.symptombusinessNiemann–Pick diseaseLysosomesVisceromegalyDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Physiological Estrogen Replacement May Enhance the Effectiveness of the Gonadotropin-Releasing Hormone Agonist in the Treatment of Hirsutism

1994

GnRH agonists (GnRH-A) have been used for the treatment of hirsutism in women with ovarian hyperandrogenism. However, significant side-effects, including vasomotor symptoms and bone loss, have prevented the long term use of this therapy. In this study, we evaluated the effects of low dose (physiological) estrogen replacement on the side-effects and clinical and hormonal parameters of 22 hirsute women with ovarian hyperandrogenism when treated with a long-acting GnRH-A, Decapeptyl. Ten patients with Ferriman-Gallwey (FG) scores averaging 13.4 +/- 1.5 were randomly assigned to be treated with Decapeptyl alone (3.75 mg, im, every 28 days for 6 months), and 12 other patients with FG scores aver…

AdultHirsutismendocrine systemmedicine.medical_specialtyAdolescentmedicine.drug_classEndocrinology Diabetes and MetabolismClinical BiochemistryOvaryMedroxyprogesterone AcetateGonadotropin-releasing hormoneBiochemistryGonadotropin-Releasing HormoneEndocrinologyGonadotropin-releasing hormone agonistInternal medicinemedicineHumansMedroxyprogesterone acetateEstrogen replacementConjugated Equine EstrogensTestosteronehirsutismTriptorelin PamoateVasomotorbusiness.industryEstrogen Replacement TherapyBiochemistry (medical)HyperandrogenismObstetrics and GynecologyDrug SynergismGeneral Medicinemedicine.diseaseMenstruationmedicine.anatomical_structureEndocrinologyEstrogenGonadotropins PituitaryAndrogensDrug Therapy CombinationFemalebusinesshormones hormone substitutes and hormone antagonistsHormonemedicine.drugObstetrical & Gynecological Survey
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