Search results for "Cement"

Muscular transcriptome in postmenopausal women with or without hormone replacement.

2007

The loss of muscle mass and strength with aging is well characterized, but our knowledge of the molecular mechanisms underlying the development of sarcopenia remains incomplete. Although menopause is often accompanied with first signs of age-associated changes in muscle structure and function, the effects of hormone replacement therapy (HRT) or menopause-related decline in estrogen production in the muscles of postmenopausal women is not well understood. Furthermore the knowledge of the global transcriptional changes that take place in skeletal muscle in relation to estrogen status has thus far been completely lacking. We used a randomized double-blinded study design together with an explor…

Intramuscular sex steroid hormones are associated with skeletal muscle strength and power in women with different hormonal status

2015

International audience; Estrogen (E2)-responsive peripheral tissues, such as skeletal muscle, may suffer from hormone deficiency after menopause potentially contributing to the aging of muscle. However, recently E2 was shown to be synthesized by muscle and its systemic and intramuscular hormone levels are unequal. The objective of the study was to examine the association between intramuscular steroid hormones and muscle characteristics in premenopausal women (n = 8) and in postmenopausal monozygotic twin sister pairs (n = 16 co-twins from eight pairs) discordant for the use of E2-based hormone replacement. Isometric skeletal muscle strength was assessed by measuring knee extension strength.…

Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference.

2009

The present study employs a conditioned place preference procedure (CPP) to examine the effects of exposure to the cannabinoid agonist WIN 55212-2 (WIN) (0.1 and 0.5mg/kg) during adolescence on the reinforcing properties of +/-3,4-methylenedioxymetamphetamine hydrochloride (MDMA) (1.25 and 2.5mg/kg) in mice. On postnatal day (PD) 27, animals received a daily injection of the assigned treatment on 5 consecutive days, and three days later the place conditioning procedure was initiated (PD 35). The results suggest that pre-exposure to cannabinoids strengthens the properties of MDMA and favors reinstatement of the craving for the drug, which endorses the gateway hypothesis.

CB1 cannabinoid receptor-mediated aggressive behavior

2013

This study examined the role of cannabinoid CB1 receptors (CB1r) in aggressive behavior. Social encounters took place in grouped and isolated mice lacking CB1r (CB1KO) and in wild-type (WT) littermates. Cognitive impulsivity was evaluated in the delayed reinforcement task (DRT). Gene expression analyses of monoaminooxidase-A (MAO-A), catechol-o-methyl-transferase (COMT), 5-hydroxytriptamine transporter (5-HTT) and 5-HT1B serotonergic receptor (5HT1Br) in the median and dorsal raphe nuclei (MnR and DR, respectively) and in the amygdala (AMY) were performed by real time-PCR. Double immunohistochemistry studies evaluated COMT and CB1r co-localization in the raphe nuclei and in the cortical (AC…

Le financement des études supérieures par l'emprunt

1973

La necrópolis tardo-antigua del Tossal de les Basses (Alicante, España): tipología y primera aproximación interpretativa y cronológica

2015

Se presenta en este artículo un resumen del estudio pormenorizado que hemos realizado sobre una importante necrópolis tardo-antigua que, hoy por hoy y pese a su extensión y número total de individuos (cerca del millar), no puede vincularse con ningún núcleo urbano de importancia. Su desarrollo desde mediados del s. IV hasta la llegada de los musulmanes a inicios del s. VIII, y la aparición de un nuevo asentamiento y necrópolis alto-medieval en sus cercanías, hacen a esta necrópolis fundamental para entender la evolución de la zona con posterioridad a la desaparición en el s. III de la ciudad romana de Lucentum. Summary of detailed study we performed on a late ancient cementery were unable t…

Behaviour of the high temperature corrosion of metals (TiAl3) coated with titanium aluminide

2010

During this study, intermetallic coatings TiAlx (x=1,2,3) were performed on titanium substrates: pure titanium and the commercial alloy, TA6V. The aim of this study was to elaborate aluminiure coatings on the surface and characterize the behaviour of these coated materials in oxidation at high temperature under air laboratory, under air enriched with water vapour and with sulfur. The coated materials were tested at three temperatures: 700°C, 800°C and 900°C. The coatings were realized at 1000°C by the pack-cementation process. The coatings realized are always adherent to the substrate. During oxidation the retrodiffusion of aluminium changes the nature of the phases and the organisation of …

Synthesis and characterisation of pack cemented aluminide coatings on metals

2004

Abstract The exposition of metallic materials to high temperature environments leads to their corrosion because of oxidation or sulphidation. One way to protect such materials is to produce an Al 2 O 3 layer which needs to be continuous enough to limit diffusion of oxygen or metallic elements, and withstand this corrosion. Since a few years, it has been proved that aluminide compounds are one of the most effective materials to achieve this goal. Indeed, they possess sufficient Al and many beneficial mechanical properties when exposed to high temperature conditions to make possible the formation of a protective Al 2 O 3 scale. This study is aimed at the elaboration of iron, nickel and molybd…

Amorphous Silicon Nanotubes via Galvanic Displacement Deposition

2013

Amorphous silicon nanotubes were grown in a single step into a polycarbonate membrane by a galvanic displacement reaction conducted in aqueous solution. In order to optimize the process, a specifically designed galvanic cell was used. SEM images, after polycarbonate dissolution, showed interconnected nanotube bundles with an average length of 18 μm and wall thickness of 38 nm.The deposited silicon was revealed by EDS analysis, whilst X-ray diffraction and Raman spectroscopy showed that nanotubes have an amorphous structure. Silicon nanotubes were also characterized by photo-electrochemical measurements that showed n-type conductivity and optical gap of ~1.6 eV. Keywords: Silicon nanotubes, …

ESRA19-0640 The effect of intravenous dexamethasone on pain relief, blood glucose and lactate levels after hip atheroplasty

2019

Background and aims Dexamethasone provides anti-inflammatory and analgesic effect, but induces hyperglycemia and may increase serum lactate. the aim was to determine the effect of dexamethasoneon analgesia, blood glucose and lactate after hip arthroplasty. Methods This prospective randomized study includes 32 patients undergoing hip replacement. It was provided SA and patients received multimodal analgesia. the experimental group received Dexamethasone 8 mg i/v before surgery and 4 mg i/v in a 6 and 12 hours after the first dose. the control group did not receive any glucocorticoids. Blood glucose and lactate were measured before surgery,at 18:00 and 6:00 on the POD1. Patients filled in a p…