Search results for "Center"

showing 10 items of 1724 documents

CONSISTENT BONE MARROW-DERIVED CELL MOBILIZATION FOLLOWING REPEATED SHORT COURSES OF GRANULOCYTE-COLONY-STIMULATING FACTOR IN PATIENTS WITH AMYOTROPH…

2009

Background and aims. The aim of this study was to evaluate and characterize the feasibility and safety of bone marrow-derived cell (BMC) mobilization following repeated courses of granulocyte-colony stimulating factor (G-CSF) in patients with amyotrophic lateral sclerosis (ALS). Methods. Between January 2006 and March 2007, 26 ALS patients entered a multicenter trial that included four courses of BMC mobilization at 3-month intervals. In each course, G-CSF (5 mu g/kg b.i.d.) was administered for four consecutive days; 18% mannitol was also given. Mobilization was monitored by flow cytometry analysis of circulating CD34(+) cells and by in vitro colony assay for clonogenic progenitors. Co-exp…

AdultMaleCancer Researchmedicine.medical_specialtySLa - trial clinico - C-GSFImmunologyAntigens CD34Bone Marrow CellsDrug Administration ScheduleColony-Forming Units AssayCell MovementInternal medicineMulticenter trialmedicineImmunology and AllergyHumansCell LineageProspective StudiesAmyotrophic lateral sclerosisProspective cohort studyGenetics (clinical)Hematopoietic Stem Cell MobilizationNeuronsTransplantationMobilizationbusiness.industryStem CellsAmyotrophic Lateral SclerosisGranulocyte-Macrophage Colony-Stimulating FactorCell DifferentiationCell BiologyMiddle Agedmedicine.diseaseHematopoietic Stem CellsBone Marrow-Derived CellHematopoietic Stem Cell MobilizationSurgeryGranulocyte colony-stimulating factorNerve RegenerationSettore MED/26 - NEUROLOGIAGranulocyte macrophage colony-stimulating factorTreatment OutcomeOncologyBiological MarkersFemalebusinessNeurogliaBiomarkersmedicine.drug
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Surgery-triggered and non surgery-triggered Bisphosphonate-related Osteonecrosis of the Jaws (BRONJ): A retrospective analysis of 567 cases in an Ita…

2011

Invasive local procedures are often reported in clinical history of patients suffering from Bisphosphonates-Related Osteonecrosis of the Jaws (BRONJ) but over 40% of spontaneous forms have been also described in literature. We compared age, gender, underlying bone disorders, bisphosphonate therapy, clinical features and surgical outcome of 205 cases (36.2%) of BRONJ non surgery-triggered (group 1) with 362 (63.8%) cases of surgery-triggered forms (group 2). Differences between group 1 and 2 were analysed using Mann-Whitney U and χ2 tests. Statistical analysis was performed using STATA 8. Zoledronate was the most used type of bisphosphonate (63.4% versus 69.0%) and the mandible was the most …

AdultMaleCancer Researchmedicine.medical_specialtyTooth extractionmedicine.medical_treatmentZoledronic AcidSettore MED/28 - Malattie OdontostomatologicheRisk FactorsClinical historySpontaneous formmedicineRetrospective analysisHumansStatistical analysisStage (cooking)AgedRetrospective StudiesAged 80 and overSurgical outcomeBone Density Conservation AgentsDiphosphonatesBRONJOrthognathic Surgical Proceduresbusiness.industryImidazolesOsteonecrosisBisphosphonates-related Osteonecrosis of the JawMiddle AgedBisphosphonateSurgeryZoledronic acidItalyOncologyMulticenter studyFemaleBisphosphonate therapyOral SurgerybusinessJaw Diseasesmedicine.drugOral Oncology
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Where is the beat in that note? Effects of attack, duration, and frequency on the perceived timing of musical and quasi-musical sounds

2019

The perceptual center (P-center) of a sound is typically understood as the specific moment at which it is perceived to occur. Using matched sets of real and artificial musical sounds as stimuli, we probed the influence of attack (rise time), duration, and frequency (center frequency) on perceived P-center location and P-center variability. Two different methods to determine the P-centers were used: Clicks aligned in-phase with the target sounds via the method of adjustment, and tapping in synchrony with the target sounds. Attack and duration were the primary cues for P-center location and P-center variability; P-center variability was found to be a useful measure of P-center shape. Consiste…

AdultMaleComputer scienceSpeech recognitionmedia_common.quotation_subjectmusiikkiBeat (acoustics)Experimental and Cognitive PsychologyProbability density functionStimulus (physiology)050105 experimental psychologyYoung AdultBehavioral NeuroscienceArts and Humanities (miscellaneous)PerceptionHumans0501 psychology and cognitive sciencesmusicCenter frequencyta515media_common05 social sciencesRangingMiddle AgedTime perceptionhavaintopsykologiaRise timeTime Perceptionta6131Auditory PerceptionFemaleperceptual psychologyJournal of Experimental Psychology: Human Perception and Performance
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Visceral infiltration of intrahepatic cholangiocarcinoma is most prognostic after curative resection - Retrospective cohort study of 102 consecutive …

2018

Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy, and therefore large unicenter series on the surgical outcome are rare in the literature, and prognostic factors for overall survival in the literature vary widely.All patients who underwent surgery for ICC were prospectively recorded. The type of resection, operative details, histological results, morbidity, mortality, overall and recurrence-free survivals as well as prognostic factors were assessed. Prognostic factors were examined by univariate and multivariate analyses. P-values0.05 were considered significant.Between January 2008 and December 2015, 102 patients underwent a resection with curative intent and were included in thi…

AdultMaleCurative resectionmedicine.medical_specialtyMultivariate analysis030230 surgeryMalignancySingle CenterDisease-Free SurvivalCholangiocarcinoma03 medical and health sciences0302 clinical medicinemedicineHepatectomyHumansNeoplasm InvasivenessIntrahepatic CholangiocarcinomaAgedRetrospective StudiesAged 80 and overAnalysis of VarianceUnivariate analysisbusiness.industryRetrospective cohort studyGeneral MedicineMiddle AgedPrognosismedicine.diseaseSurgeryVisceraBile Ducts IntrahepaticTreatment OutcomeBile Duct Neoplasms030220 oncology & carcinogenesisFemaleSurgerybusinessInfiltration (medical)International Journal of Surgery
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Time and frequency analysis of the static balance in young adults with Down syndrome

2010

The main objective of this study is to understand the differences in equilibrium control between normal subjects and those with Down syndrome. A total of 54 subjects participated voluntarily, divided into control group and Down syndrome group. The equilibrium of the subjects was tested under two conditions: bipedal support with eyes open and closed. The signals were analyzed in a time and frequency domain. The statistical parameters selected (i.e., RMS distance, mean velocity, mean frequency and sway area) to analyze the behavior of the center of pressures (CoP) are calculated employing the result of the combination of the time series data in both directions (i.e. resultant distance). In or…

AdultMaleDown syndromemedicine.medical_specialtyMovementFast Fourier transformBiophysicsAudiologylaw.inventionYoung AdultCenter of pressure (terrestrial locomotion)lawPostural BalancemedicineHumansOrthopedics and Sports MedicineTime domainPostural BalanceSimulationMathematicsVestibular systemFrequency analysisRehabilitationmedicine.diseaseTime and Motion StudiesFrequency domainFemaleDown SyndromeGait & Posture
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Prospective, cross-over, single-center trial comparing oral double-balloon enteroscopy and oral spiral enteroscopy in patients with suspected small-b…

2011

BACKGROUND AND STUDY AIMS: Spiral enteroscopy is a new, promising rapid enteroscopy technique. A prospective cross-over study was carried out to compare this new method with the established technique of double-balloon enteroscopy (DBE). PATIENTS AND METHODS: From an initial group of 18 patients with suspected mid-gastrointestinal bleeding due to vascular malformations but no previous history of small-bowel or colonic surgery, 10 patients (mean age 69 years) completed the study. Patients underwent both enteroscopy techniques with an oral approach, in a randomized sequence. The deepest point reached during advancement in the first enteroscopy was marked with India ink. The primary end point o…

AdultMaleEnteroscopymedicine.medical_specialtySingle CenterEndoscopy GastrointestinalAngiodysplasiaDouble-balloon enteroscopyIntestine SmallmedicineHumansIn patientProspective StudiesAngiodysplasiaProspective cohort studySpiralAgedDouble-Balloon EnteroscopyCross-Over Studiesmedicine.diagnostic_testbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseSurgeryEndoscopyEndoscopes GastrointestinalIntestinal DiseasesTime and Motion StudiesFemaleRadiologyGastrointestinal HemorrhagebusinessEndoscopy
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Italian Health Care Workers’ Knowledge, Attitudes, and Practices Regarding Human Papillomavirus Infection and Prevention

2020

Objective: To assess healthcare workers&rsquo

AdultMaleHealth Knowledge Attitudes Practicemedicine.medical_specialtyHPVknowledgegenetic structuresHealth PersonnelHealth Toxicology and MutagenesisUterine Cervical Neoplasmslcsh:MedicineScientific literatureimmunizationSettore MED/42 - Igiene Generale E ApplicataArticle03 medical and health sciences0302 clinical medicinepreventionAttitude Awareness Healthcare workers HPV Immunization Knowledge Practice Prevention Sexually transmitted infection Adult Cross-Sectional Studies Female Italy Middle Aged Papillomavirus Vaccines Papillomavirus Infections Uterine Cervical NeoplasmsSurveys and QuestionnairesvaccineIntervention (counseling)Health caremedicineHumansAttitude; Awareness; Healthcare workers; HPV; Immunization; Knowledge; Practice; Prevention; Sexually transmitted infection; VaccineawarenessPapillomavirus Vaccinessexually transmitted infection030212 general & internal medicineHuman papillomavirusbusiness.industryhealthcare workersPapillomavirus Infectionslcsh:RPublic Health Environmental and Occupational HealthMiddle AgedProduct characteristicspracticeCross-Sectional StudiesItaly030220 oncology & carcinogenesisFamily medicineattitudeMulticenter surveyPropensity score matchingFemalebusinessInternational Journal of Environmental Research and Public Health
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No detection of occult HBV-DNA in patients with various rheumatic diseases treated with anti-TNF agents: a two-year prospective study.

2013

OBJECTIVES: The widespread use of tumour necrosis factor (TNF)-targeted therapies in patients with rheumatic, digestive and dermatologic diseases has been associated with reports of reactivation of HBV replication and ensuing hepatitis flares both in asymptomatic HBsAg carriers and in subjects with occult HBV infection. The aim of our work was to investigate in a two-year prospective study the potential for HBV reactivation in patients with inflammatory joint diseases undergoing anti-TNF treatment from a southern Mediterranean area. METHODS: Fifty-seven consecutive outpatients attending the Academic Unit of Rheumatology at the University of Palermo (12 with rheumatoid arthritis, 17 with pso…

AdultMaleHepatitis B virusTime Factorsoccult HBV-DNAAntiviral AgentsPolymerase Chain ReactionRisk AssessmentRisk FactorsRheumatic Diseasesoccult HBV-DNA rheumatic diseases anti-TNFHumansProspective Studiesrheumatic diseaseAcademic Medical CentersHepatitis B Surface AntigensTumor Necrosis Factor-alphavirus diseasesanti-TNFMiddle AgedHepatitis Bdigestive system diseasesTreatment OutcomeItalyLamivudineAntirheumatic AgentsDNA ViralFemaleVirus ActivationBiomarkers
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Effects of kinematics constraints on hand trajectory during whole-body lifting tasks

2000

Trajectories of the hands and whole-body center of mass were studied during whole-body lifting tasks. The movements of different parts of the body were monitored with the ELITE system. Subjects were instructed to lift to shoulder height an object placed at one of two distances (5-45 cm) before them on the floor. The lifts were performed both with and without kinematics constraints (i.e. to produce a straight hand trajectory while lifting, and to lift without any instructions, respectively). Hand trajectories were roughly straight when performed under the constrained condition, but curved when performed without instruction. Hand velocity curves showed bell-shaped profiles. In both groups, bo…

AdultMaleLiftingHand StrengthMovement (music)MovementGeneral NeurosciencePostureBody movementKinematicsHandSagittal planeBiomechanical PhenomenaLift (force)medicine.anatomical_structureControl theoryTrajectorymedicineHumansCenter of massInvariant (mathematics)MathematicsNeuroscience Letters
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A satisfaction survey of opioid-dependent clients at methadone treatment centres in Spain

2002

A survey was carried out to evaluate the satisfaction with methadone treatment centres of methadone-maintained opioid-dependent patients from Spain. Independent interviewers asked 505 consecutively arriving clients from 20 randomly selected centres (14 conventional centres, two bus units, and four prisons) to participate; 370 (73.3%) clients agreed to fill out the questionnaire, and 351 (69.5%) completed it. Satisfaction was assessed using the Verona Service Satisfaction Scale for methadone treatment (VSSS-MT). The prison sub-sample (n=43) was excluded from overall analysis because survey acceptance and satisfaction was very different in prisons than in the other centres. Mean overall satis…

AdultMaleMental Health ServicesNarcoticsmedicine.medical_specialtyAdolescentService satisfactionPsychological interventionToxicologySurveys and QuestionnairesHumansMedicinePharmacology (medical)PsychiatryPharmacologyAnalysis of Variancebusiness.industryOpioid dependentRegression analysisMiddle AgedOpioid-Related DisordersPsychiatry and Mental healthPatient SatisfactionSpainFamily medicineFemaleSubstance Abuse Treatment CentersbusinessMethadoneMethadonemedicine.drugDrug and Alcohol Dependence
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