Search results for "Cercopithecu"
showing 8 items of 8 documents
In vitro antileishmanial activity of trans-stilbene and terphenyl compounds
2016
Leishmaniasis are globally widespread parasitic diseases which often leads to death if left untreated. Currently available drugs present different drawbacks, so there is an urgent need to develop new, safe and cost-effective drugs against leishmaniasis. In this study we tested a small library of trans-stilbene and terphenyl derivatives against promastigote, amastigotes and intramacrophage amastigote forms of Leishmania infantum. Two compounds of the series, the trans-stilbene 3 and the terphenyl 11, presented the best activity and safety profiles. Terphenyl 11 showed a leshmanicidal activity higher than pentostam and the ability to induce apoptosis selectively in Leishmania infantum while s…
Guenon Radiation is Enriched by a New Species that Demonstrates an Evolutionary Complexity with Which we are yet to Become Familiar
2012
th September described this discovery to the scientific community (1). As is becoming increasingly frequent these days, given the high number of scientific articles, the media news reached us faster than the scientific information. The area known as TL2, a few hundred km as the crow flies south- west from the city of Kisangani, famous for its manufacturing, and important port on the Zaire river, is still uncontaminated and houses several important endemisms. This new species, studied in the area since 2007, on the basis of first sightings by the inhabitants of the zone and local hunters, has been named Cercopithecus lomamiensis. C.lomamiensis (CLO) is a tree-dweller and has been described i…
Preliminary data on cytogenetics and cytotaxonomy of Cercopithecus albogoularis labiatus (Samango monkey)
2010
Preliminary data on cytogenetics and cytotaxonomy of Cercopithecus albogoularis labiatus (Samango monkey) L. Sineo1, M. Roccella1, B. Picone1, R. Stanyon2, F. Genin3 and J. Masters 3 1Dipartimento di Biologia animale, Università di Palermo, Italia; 2Dipartimento di Biologia evoluzionistica, Università di Firenze, Italia; 3Department of Zoology and Entomology, University of Fort Hare, Alice, South Africa The systematic status and phylogenetic relationships of the C. mitis “species group” are contentious. The species group effectively includes very different species (C. nictitans, C. mitis, and C. albogularis) with wide, reciprocally remote distribution in Africa, and high regional variabilit…
Dinamica cromosomica ed evoluzione nei Cercopithecini
2011
Chromosomal Dynamics in Cercopithecini Studied by Williams-Beuren probe mapping
2010
Chromosomal evolution in the tribe Cercopithecini and in related taxa is highly debated. Uncertainty in reconstruction is mainly related to the great genetic variability and polymorphism of the taxa. Recent molecular and karyological efforts individuate a split between genetically conservative, arbitrarily defi ned, “terrestrial” guenons and vervets, and genetically variable and derived “arboreal” guenons. We performed the mapping of WS loci probe (7q11.23) in order to verify the chromosomal dynamics of the genomes of three tree-dwelling species of the tribe: C. neglectus, C. mitis mitis, C. albogularis labiatus. Data from literature for the “ground-dwelling” Chlorocebus aethiops sabaeus ha…
Novel mutations of CETP gene in Italian subjects with hyeralphalipoproteinemia
2009
Abstract Cholesteryl ester transfer protein (CETP) is a plasma glycoprotein that catalyses the transfer of cholesteryl esters from HDL to the other plasma lipoproteins. Genetic deficiency of CETP is one of the known causes of elevation of plasma HDL-C (primary hyperalphalipoproteinemia, HALP). We sequenced CETP gene in a group of 24 Italian subjects with primary HALP (HDL-C>80 mg/dl) suspected to have CETP deficiency. Two unrelated subjects both coming from the same geographical district, were found to be heterozygous for a nucleotide substitution in exon 6 (c.544C>T) and another subject was found to be heterozygous for a C>T transition in exon 9 (c.802C>T). Both mutations introduce a prema…
Degree of terrestrial activity of the elusive sun-tailed monkey (Cercopithecus solatus) in Gabon: Comparative study of behavior and postcranial morph…
2015
We carried out a multidisciplinary study linking behavioral and morphological data from a little-known guenon species, Cercopithecus solatus, endemic to Gabon. Over a period of 9 months, we documented the pattern of stratum use associated with postural and locomotor behavior by direct observation (650 hrs) of a semi-free-ranging breeding colony. We also conducted a morphometric analysis of the humerus and limb proportions of 90 adult specimens from 16 guenon species, including C. solatus. Field observations indicated that C. solatus monkeys spent a third of their time on the ground, similar to semi-terrestrial guenon species. We detected two patterns of stratum use: at ground level, and in …