Search results for "Cero"

showing 10 items of 691 documents

Membrane glycerolipid remodeling triggered by nitrogen and phosphorus starvation in Phaeodactylum tricornutum.

2014

International audience; Diatoms constitute a major phylum of phytoplankton biodiversity in ocean water and freshwater ecosystems. They are known to respond to some chemical variations of the environment by the accumulation of triacylglycerol, but the relative changes occurring in membrane glycerolipids have not yet been studied. Our goal was first to define a reference for the glycerolipidome of the marine model diatom Phaeodactylum tricornutum, a necessary prerequisite to characterize and dissect the lipid metabolic routes that are orchestrated and regulated to build up each subcellular membrane compartment. By combining multiple analytical techniques, we determined the glycerolipid profil…

0106 biological sciencesPhysiologyPlant ScienceThylakoids01 natural sciencesPhaeodactylum tricornutumTranscriptomeMGDGNutrientnutrient starvationLipids metabolismSettore BIO/04 - Fisiologia VegetaleDigalactosyldiacylglycerolPhospholipids0303 health sciencesbiologyNitrogen starvationmicroalgaeMonogalactosyldiacyglycerolPhosphorusArticlesAdaptation PhysiologicalBiochemistryThylakoidSulfoquinovosyldiacylglycerollipids (amino acids peptides and proteins)DGDGNitrogenchemistry.chemical_elementlipidsMembrane Lipids03 medical and health sciencesSQDG[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyGenetics[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology14. Life underwaterPhaeodactylum tricornutumTriglycerides030304 developmental biologyDiatomsMembranesGene Expression ProfilingPhosphorusfungiPhosphorus starvationGlycerolipidsLipid metabolismmetabolic pathwaybiology.organism_classificationMetabolic pathwayPhosphatidylcholineDiatomchemistryPhytoplanktonLipidomics010606 plant biology & botany
researchProduct

Stabilization of an enzymatic extract from Penicillium camemberti containing lipoxygenase and hydroperoxide lyase activities

2008

International audience; The stabilization of an enzymatic extract, obtained from Penicillium camemberti containing lipoxygenase (LOX) and hydroperoxide lyase (HPL) activities, was investigated using selected additives. Although the addition of KCl (86%, w/w) to the enzymatic extract decreased slightly (7%) the LOX activity, it increased HPL activity by 2.25 fold; however, the addition of dextran resulted in the inactivation of both enzymatic activities. The stability of the solid lyophilized enzymatic extract was greater in the presence of KCl than that without it, with ∼100% residual activity after 8 and 4 weeks of storage at −80 °C, for LOX and HPL, respectively. The rate constants of ina…

0106 biological sciencesSucroseLipoxygenaseBioengineering01 natural sciencesApplied Microbiology and BiotechnologyBiochemistryHydroperoxide lyase03 medical and health scienceschemistry.chemical_compoundLipoxygenase010608 biotechnologyGlycerolmedicine[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology030304 developmental biologyThermostabilitychemistry.chemical_classification0303 health sciencesbiologyPenicillium camembertiAdditivesbiology.organism_classificationStabilizationDextranEnzymechemistryBiochemistryPenicillium camembertibiology.proteinMannitolmedicine.drug
researchProduct

Genome sequence of the pea aphid Acyrthosiphon pisum

2010

The genome of the pea aphid shows remarkable levels of gene duplication and equally remarkable gene absences that shed light on aspects of aphid biology, most especially its symbiosis with Buchnera.

0106 biological sciencesTANDEM REPEATSGenome InsectGene TransferRRES175Sequència genòmicaFaculty of Science\Computer ScienceCPG METHYLATION01 natural sciencesGenomeMedical and Health SciencesInternational Aphid Genomics ConsortiumBiologiska vetenskaperBiology (General)GENE-EXPRESSION2. Zero hungerGenetics0303 health sciencesAphidGenomeAfídidsGeneral NeuroscienceGENOME SEQUENCEfood and beveragesDROSOPHILA CIRCADIAN CLOCKBiological SciencesGenetics and Genomics/Microbial Evolution and GenomicsINSECTEGenètica microbianapuceronAPIS-MELLIFERAGeneral Agricultural and Biological SciencesInfectionsymbioseBiotechnologyResearch ArticleVIRUS VECTORING175_GeneticsSYMBIOTIC BACTERIAGene Transfer HorizontalQH301-705.5ACYRTHOSIPHON PISUMBiologyHOLOMETABOLOUS INSECTSHOST-PLANT010603 evolutionary biologyGENOME SEQUENCE;PEA APHID;ACYRTHOSIPHON PISUM;INSECT-PLANT;HOST-PLANT;VIRUS VECTORING;PHENOTYPIC PLASTICITY;HOLOMETABOLOUS INSECTS;INSECTE;RAVAGEUR DES CULTURES; SOCIAL INSECTGeneral Biochemistry Genetics and Molecular BiologyHorizontal03 medical and health sciencesBuchneraPHENOTYPIC PLASTICITYINSECT-PLANTGeneticsGene familyLife ScienceAnimalsSymbiosisGene030304 developmental biologyWhole genome sequencingGeneral Immunology and MicrobiologyAnnotation; Aphid; Genome sequenceAgricultural and Veterinary Sciences175_EntomologyGenètica animalBacteriocytegénomegèneHuman GenomePEA APHIDBiology and Life Sciences15. Life on landbiochemical phenomena metabolism and nutritionbiology.organism_classificationREPETITIVE ELEMENTSDNA-SEQUENCESAcyrthosiphon pisumGenome SequenceGenetics and Genomics/Genome ProjectsRAVAGEUR DES CULTURESAphidsPHEROMONE-BINDINGBuchneraInsectDevelopmental Biology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
researchProduct

Molecular phylogeny of the extinct giant deer, Megaloceros giganteus.

2006

a Centre de Genetique Moleculaire et Cellulaire (CGMC), CNRS UMR 5534, Universite Claude Bernard Lyon 1, Villeurbanne, France b Laboratoire d’Anthropologie des Populations du Passe, CNRS UMR 5199 PACEA, Universite Bordeaux 1, Talence, France c UCD School of Biology and Environmental Science, UCD, BelWeld, Dublin 4, Ireland d Laboratoire d’Ecologie des Hydrosystemes Fluviaux, CNRS UMR 5023, Universite Claude Bernard Lyon 1, Villeurbanne, France e Biogeosciences-Dijon, CNRS UMR 5561, Universite de Bourgogne, Centre des Sciences de la Terre, Dijon, France f Department of Palaeontology, Royal Belgian Institute of Natural Sciences, Brussels, Belgium g Department of Biology, University College Lo…

0106 biological sciencesTime FactorsMESH: GeographyMESH: Base Sequence[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy01 natural sciencesMESH: FossilsMESH : BiodiversityMESH: AnimalsMESH: PhylogenyGiant deerPhylogenyComputingMilieux_MISCELLANEOUS[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/Paleontology0303 health sciencesbiologyAncient DNAGeographyEcologymtDNAFossils[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]MegalocerosMESH : GeographyClaude bernardBiodiversityMESH : Deer[ SDV.GEN.GPO ] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE][SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyMESH : Time Factors[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]MESH: Deer010603 evolutionary biologyMESH: BiodiversityQuaternary03 medical and health sciencesGeneticsAnimals14. Life underwaterMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyBase SequenceDeerMESH: Time FactorsMESH : Phylogenybiology.organism_classificationMESH : FossilsMESH : Base SequenceMESH : AnimalsHumanities[ SDV.BID.SPT ] Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy
researchProduct

Effects of gellan-based coating application on litchi fruit quality traits

2018

The use of gellan-based coating formulation on litchi (Litchi chinensis Sonn. ‘Wai Chee’) fruit was investigated in order to determine its ability to improve color conservation and to maintain the overall quality. Fruits were treated with gellanbased coating (0.5% w/v) and glycerol (3% w/v) after dipping in ascorbic acid (1.5% w/v) and then stored at 5°C and 90% relative humidity for 15 days. Changes in peel color, soluble solid content, tritatable acidity, weight loss, antioxidant activity and phenolic content, were measured. Formulations containing gellan-based coating exhibited slightly improved water barrier properties and showed their active role in maintaining color characteristics an…

0106 biological sciencesTitratable acid04 agricultural and veterinary sciencesHorticultureengineering.materialAscorbic acid01 natural sciencesGellan gumSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreechemistry.chemical_compoundLitchi fruitLitchi chinensis ‘Wai Chee’ color phenolic content ascorbic acid antioxidant activitychemistryCoatingSoluble solidsSettore BIO/10 - Biochimica040103 agronomy & agricultureGlycerolengineering0401 agriculture forestry and fisheriesRelative humidityFood science010606 plant biology & botanyActa Horticulturae
researchProduct

Free Radicals Mediate Systemic Acquired Resistance

2014

Summary: Systemic acquired resistance (SAR) is a form of resistance that protects plants against a broad spectrum of secondary infections. However, exploiting SAR for the protection of agriculturally important plants warrants a thorough investigation of the mutual interrelationships among the various signals that mediate SAR. Here, we show that nitric oxide (NO) and reactive oxygen species (ROS) serve as inducers of SAR in a concentration-dependent manner. Thus, genetic mutations that either inhibit NO/ROS production or increase NO accumulation (e.g., a mutation in S-nitrosoglutathione reductase [GSNOR]) abrogate SAR. Different ROS function additively to generate the fatty-acid-derived azel…

0106 biological sciences[SDV]Life Sciences [q-bio]ArabidopsisPseudomonas syringaeReductasemedicine.disease_cause01 natural scienceschemistry.chemical_compoundcuticle formationInducerDicarboxylic Acidsskin and connective tissue diseaseslcsh:QH301-705.5chemistry.chemical_classification0303 health sciencesMutationsalicyclic-acidCell biologydefenseGlutathione ReductaseBiochemistryGlycerophosphates[SDE]Environmental Sciencesplant immunitySystemic acquired resistances-nitrosoglutathioneSecondary infectionnitric-oxidearabidopsis-thalianaBiologyNitric OxideGeneral Biochemistry Genetics and Molecular BiologyNitric oxide03 medical and health sciencesmedicine[SDV.BV]Life Sciences [q-bio]/Vegetal Biology030304 developmental biologyReactive oxygen speciesArabidopsis Proteinsfungicell-deathbody regionschemistrylcsh:Biology (General)azelaic-acidresponsesNitric Oxide SynthaseReactive Oxygen SpeciesFunction (biology)010606 plant biology & botanynitric-oxide;plant immunity;arabidopsis-thaliana;s-nitrosoglutathione;cuticle formation;salicyclic-acid;azelaic-acid;cell-death;responses;defenseCell Reports
researchProduct

Happens in the best of subfamilies: establishment and repeated replacements of co-obligate secondary endosymbionts within Lachninae aphids.

2016

SummaryVirtually all aphids maintain an obligate mutualistic symbiosis with bacteria from theBuchneragenus, which produce essential nutrients for their aphid hosts. Most aphids from the Lachninae subfamily have been consistently found to house additional endosymbionts, mainlySerratia symbiotica. This apparent dependence on secondary endosymbionts was proposed to have been triggered by the loss of the riboflavin biosynthetic capability byBuchnerain the Lachninae last common ancestor. However, an integral large-scale analysis of secondary endosymbionts in the Lachninae is still missing, hampering the interpretation of the evolutionary and genomic analyses of these endosymbionts. Here, we anal…

0301 basic medicine0106 biological sciencesMost recent common ancestorSerratiaSubfamily[SDV]Life Sciences [q-bio]aphididaeinteraction hôte symbioteBiologyMicrobiology010603 evolutionary biology01 natural sciencesSerratia03 medical and health sciencesSymbiosisPhylogeneticsAnimalsbuchneraPhylogenyEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesAphidObligatefungifood and beveragesbiochemical phenomena metabolism and nutritionbiology.organism_classificationbactérie endosymbiotiquesymbiosis030104 developmental biologyEvolutionary biologypuceronAphidsTissue tropismbacteriaBuchnerasymbioseBacteria
researchProduct

Expression of NF-κB and IL-6 in oral precancerous and cancerous lesions: An immunohistochemical study.

2014

Background The purpose of this study was to evaluate the immunohistochemical expression of NF-κB and IL-6 in oral premalignant and malignant lesions and to investigate their possible correlation with the presence of subepithelial inflammation. Material and Methods Thirty two oral premalignant lesions, clinically compatible with leukoplakia or erythroplakia, were investigated. Microscopically, 11 of them showed hyperkeratosis and acanthosis (epithelial hyperplasia) and 21 showed dysplasia of varying degrees. Nine cases of OSCC and four control cases of normal oral mucosa were also included in the study. Immunohistochemical staining with NF-κB (p65) and IL-6 was performed. IL-6 and nuclear NF…

0301 basic medicineAdultMalePathologymedicine.medical_specialtyHyperkeratosisOdontologíaAcanthosis03 medical and health sciences0302 clinical medicineMedicineHumansGeneral DentistryLeukoplakiaAgedMouth neoplasmAged 80 and overErythroplakiaOral Medicine and Pathologybusiness.industryInterleukin-6ResearchNF-kappa BMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludImmunohistochemistrystomatognathic diseases030104 developmental biologyOtorhinolaryngologyDysplasia030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASImmunohistochemistrySurgeryFemaleMouth NeoplasmsbusinessPrecancerous ConditionsImmunostainingLeukoplakiaMedicina oral, patologia oral y cirugia bucal
researchProduct

Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions.

2020

Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis and cardiovascular diseases. It is characterised by mitochondrial dysfunction and the presence of oxidative stress. Metformin is one of the safest and most effective anti-hyperglycaemic agents currently employed as first-line oral therapy for T2D. It has demonstrated additional beneficial effects, unrelated to its hypoglycaemic action, on weight loss and several diseases, such as cancer, cardiovascular disorders and metabolic diseases, including thyroid diseases. Despite the vast clinical experience gained over several decades of use, the mechanism of action of metformin i…

0301 basic medicineAdvanced glycation end product (AGE)AMP-activated protein kinase (AMPK)endocrine system diseasesglycerol 3-phosphate dehydrogenase (GPD)Clinical Biochemistrytype 1 diabetes (T1D)Type 2 diabetesmTORC1Review Articleelectron transport chain (ETC)PharmacologyMitochondrionmedicine.disease_causeBiochemistry0302 clinical medicineLeukocytesCREB-binding protein (CBP)inner mitochondrial membrane (IMM)lcsh:QH301-705.5lcsh:R5-920cAMP response element-binding (CREB)glucagon-like peptide 1 (GLP-1)type 2 diabetes (T2D)Type 2 diabetesMetforminMetforminMitochondriamedicine.anatomical_structurereactive nitrogen species (RNS)reactive oxygen species (ROS)sirtuin (SIRT)medicine.symptomlcsh:Medicine (General)cardiovascular diseases (CVD)medicine.drugEndotheliumnitric oxide synthase (NOS)polycystic ovary syndrome (PCOS)Pathophysiologyinsulin resistance (IR)superoxide dismutase (SOD)03 medical and health sciencesglycated haemoglobin (HbA1c)medicineorganic cation transporter (OCT)HumansEndotheliumintercellular adhesion molecule-1 (ICAM-1)business.industryoxidative phosphorylation (OXPHOS)Organic Chemistryperoxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α)AMPKmedicine.diseaseAtherosclerosisvascular cell adhesion molecule-1 (VCAM-1)Treatment030104 developmental biologylcsh:Biology (General)Mechanism of actionDiabetes Mellitus Type 2Oxidative stressbusinessinsulin receptor substrate (IRS)030217 neurology & neurosurgeryOxidative stress
researchProduct

Middle Pleistocene protein sequences from the rhinoceros genus Stephanorhinus and the phylogeny of extant and extinct Middle/Late Pleistocene Rhinoce…

2017

BackgroundAncient protein sequences are increasingly used to elucidate the phylogenetic relationships between extinct and extant mammalian taxa. Here, we apply these recent developments to Middle Pleistocene bone specimens of the rhinoceros genusStephanorhinus. No biomolecular sequence data is currently available for this genus, leaving phylogenetic hypotheses on its evolutionary relationships to extant and extinct rhinoceroses untested. Furthermore, recent phylogenies based on Rhinocerotidae (partial or complete) mitochondrial DNA sequences differ in the placement of the Sumatran rhinoceros (Dicerorhinus sumatrensis). Therefore, studies utilising ancient protein sequences from Middle Pleis…

0301 basic medicineAncient proteinsBioinformaticsZoologylcsh:MedicineRhinocerosProtein degradationBiologyRhinocerotidaeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesWoolly rhinocerosbiology.animalMolecular BiologyStephanorhinusStephanorhinusGeneral Neurosciencelcsh:RPaleontologyPalaeoproteomicsGeneral MedicineCoelodontabiology.organism_classificationDicerorhinus sumatrensisEquusEvolutionary StudiesPhylogenetics030104 developmental biologyEvolutionary biologyEquidaeGeneral Agricultural and Biological Sciences
researchProduct