Search results for "Cervical"

showing 10 items of 511 documents

Morbidity after pelvic exenteration for gynecological malignancies: a retrospective multicentric study of 230 patients.

2013

ObjectiveOur study purpose was to evaluate morbidity and postoperative mortality in patients who underwent pelvic exenteration (PE) for primary or recurrent gynecological malignancies.MethodsWe identified 230 patients who underwent PE, referred to the gynecological oncology units of 4 institutions: Charitè University in Berlin, Friedrich-Schiller University in Jena, S. Orsola-Malpighi University in Bologna, and Catholic University in Rome and in Campobasso.ResultsThe median age was 55 years. The tumor site was the cervix in 177 patients, the endometrium in 28 patients, the vulva in 16 patients, and the vagina in 9 patients. Sixty-eight anterior, 31 posterior, and 131 total PEs were performe…

Adultmedicine.medical_specialtyGenital Neoplasms Femalemedicine.medical_treatmentYoung AdultRetrospective StudieGermanymedicineHumansPostoperative PeriodMortalityAgedRetrospective StudiesAged 80 and overCervical cancerVaginal cancerHysterectomyGynecological malignanciePelvic exenterationbusiness.industryEndometrial cancerMortality rateGynecological malignanciesObstetrics and GynecologyPerioperativeMiddle AgedVulvar cancermedicine.diseaseSurvival AnalysisPelvic ExenterationSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAItalyOncologyFemaleSurvival AnalysiMorbidityMorbidity pelvic exenteration gynecological malignanciesbusinessHuman
researchProduct

Ticlopidine in the Treatment of Multiple Atherosclerotic Arteriopathy: a Strain Gauge Plethysmography and Döppler Spectrum Analysis Evaluation

1987

The effect of ticlopidine was compared with flunarizine in patients with iliac–femoral and / or femoral–popliteal arteriosclerotic arteriopathy accompanied by lesions of the cervical arteries of no haemodynamic significance. In the lower limbs, plethysmography (strain gauge measurements) and Döppler ultrasonography integrated by spectral analysis of the cervical arteries showed qualitative and quantitative improvements of the regional haematic flow. Side-effects were negligible which suggests that ticlopidine is useful in the treatment of multiple arteriosclerotic arteriopathy.

medicine.medical_specialtyPathologyTiclopidineArteriosclerosisCervical ArteryHemodynamics030204 cardiovascular system & hematologyBiochemistry03 medical and health sciencessymbols.namesake0302 clinical medicineInternal medicineHumansMedicinePlethysmograph030212 general & internal medicineTiclopidineFlunarizineAgedUltrasonographybusiness.industryVascular diseaseBiochemistry (medical)Cell BiologyGeneral MedicineMiddle Agedmedicine.diseasePlethysmographyCardiologysymbolsbusinessDoppler effectBlood Flow VelocityFlunarizinemedicine.drugStrain gauge plethysmographyJournal of International Medical Research
researchProduct

Cervical necrotizing fasciitis and descending necrotizing mediastinitis in a patient affected by neglected peritonsillar abscess: a case of medical n…

2007

Abstract We report a case of fatal cervical necrotizing fasciitis (CNF) and descending necrotizing mediastinitis (DNM) due to primary peritonsillar abscess in 60-year-old male patient with no history or evidence of immunocompromising disorders. The patient was treated with antibiotic and corticosteroid drugs but he developed mediastinitis and septic shock and died of multiple organ failure six days later from recovery in hospital. After a clinical, diagnostic and therapeutical consideration of the cervical necrotizing fasciitis and some related risks of a delayed diagnosis and treatment, the authors analysed the clinical history of the patient and of the medical conduct pointing out profess…

Malemedicine.medical_specialtyMultiple Organ FailureDelayed diagnosisPathology and Forensic MedicineFatal OutcomeSettore MED/43 - Medicina LegaleAdrenal Cortex HormonesMalpracticemedicineHumansFasciitis NecrotizingPeritonsillar AbscessFasciitisForensic PathologyLymphatic DiseasesPatient affectedbusiness.industrySeptic shockMalpracticeGeneral MedicinePeritonsillar AbscessMiddle Agedmedicine.diseaseMediastinitisPeritonsillar abscess cervical necrotizing fasciitis medical negligenceSurgeryAnti-Bacterial AgentsMediastinitisItalyMedical negligencebusinessLawJournal of forensic and legal medicine
researchProduct

Prevalence of carotid artery calcifications among 2,500 digital panoramic radiographs of an adult Brazilian population

2018

Background The aim of the present study was to analyze the epidemiological data of digital panoramic radiographs revealing suggestive images of carotid artery calcifications (CAC) from a Northeast Brazilian population. Material and Methods A cross-sectional retrospective study was conducted with 2,500 digital panoramic radiographs obtained from a single imaging reference center in Northeast Brazil. Images from individuals of both sexes and older than 18 years were included and those that did not cover the region of cervical vertebrae or presented low radiographic quality were excluded. Data were analyzed regarding prevalence, location (bilateral, right or left), sex, and age using the Chi-s…

Carotid Artery DiseasesMalemedicine.medical_specialtyCross-sectional studyCarotid arteriesRadiography030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineStatistical significanceRadiography PanoramicEpidemiologyPrevalencemedicineHumansVascular CalcificationGeneral DentistryAgedRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Cross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASFemaleSurgeryBrazilian populationRadiologybusinessBrazilCervical vertebrae
researchProduct

Abnormal Somatosensory Evoked Potentials Indicate Compressive Cervical Myelopathy in Mucopolysaccharidoses

2000

Compressive myelopathy at the cranio-cervical junction is a complication of mucopolysaccharidoses (MPS). To detect cervical myelopathy we recorded median and posterior tibial nerve SEPs in 15 patients aged 2.4 - 33.4 years (median 8.8 years) with MPS I-S (n = 3), MPS IVA (n = 8) and MPS VI (n = 4). In addition to the cortical waveforms we recorded the subcortical median nerve SEPs N13b and P13 generated near the cranio-cervical junction and the lemniscal P30 after posterior tibial nerve stimulation. MRI studies in 13 subjects revealed spinal cord compression at the cranio-cervical junction in 10 patients; 5 patients had an increased signal intensity on the T2-weighted initial MRI indicating…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyAdolescentSensitivity and SpecificityCentral nervous system diseaseMyelopathySpinal cord compressionEvoked Potentials SomatosensorymedicineHumansChildbusiness.industryGeneral MedicineCervical cord compressionMucopolysaccharidosesmedicine.diseaseSpinal cordMagnetic Resonance ImagingMedian nerveMedian NerveSurgerybody regionsmedicine.anatomical_structureSpinal CordSomatosensory evoked potentialChild PreschoolPediatrics Perinatology and Child HealthFemaleNeurology (clinical)RadiologyTibial NervebusinessSpinal Cord CompressionMyelomalaciaNeckNeuropediatrics
researchProduct

A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis

1987

In a long-term multicenter open trial involving 10 general practitioners, the efficacy and tolerance of S-adenosylmethionine (SAMe) were studied for 24 months in 108 patients with osteoarthritis of the knee, hip, and spine. At the end of the 24-month observation period, 97 of the patients were still in the study. The patients received 600 mg of SAMe daily (equivalent to three tablets of 200 mg each) for the first two weeks and thereafter 400 mg daily (equivalent to two tablets of 200 mg each) until the end of the 24th month of treatment. Separate evaluations were made for osteoarthritis of the knee, hip, cervical spine, and dorsal/lumbar spine. The severity of the clinical symptoms (morning…

MaleS-Adenosylmethioninemedicine.medical_specialtyClinical effectivenessOsteoarthritisOsteoarthritisHumansMedicineLongitudinal StudiesAdverse effectAgedClinical Trials as TopicPsychological TestsDepressionbusiness.industryAnti-Inflammatory Agents Non-SteroidalMorning stiffnessGeneral MedicineMiddle Agedmedicine.diseaseCervical spineSurgeryClinical trialFemaleLumbar spineOpen labelbusinessThe American Journal of Medicine
researchProduct

p53 mutations are common in human papillomavirus type 38-positive non-melanoma skin cancers

2004

Copyright © 2003 Elsevier Ireland Ltd. All rights reserved.

Keratinocytesp53Human papillomavirusCancer ResearchE6 proteinSkin NeoplasmsNon-melanoma-skin cancerImmunoblottingmedicine.disease_causePolymerase Chain ReactionmedicineAnimalsHuman papillomavirusCodonPapillomaviridaeGeneCells CulturedE6integumentary systemReverse Transcriptase Polymerase Chain Reactionbusiness.industryDNAExonsCervical cellsFibroblastsGenes p53Coculture TechniquesRatsRetroviridaeOncologyMutationCancer researchCarcinogenesisbusinessNon melanomaCancer Letters
researchProduct

DEGENERATIVE CERVICAL MYELOPATHY: REVIEW OF SURGICAL OUTCOME PREDICTORS AND NEED FOR MULTIMODAL APPROACH

2020

Degenerative cervical myelopathy is the most common cause of spinal cord injury in the elderly population in the developed world, and it significantly affects the quality of life of patients and their caregivers. Surgery remains the only treatment option able to halt disease progression and provide neurological recovery for most patients. Although it has remained challenging to predict exactly who will experience improvement after surgery, increasingly it has been shown that clinical, imaging, and electrophysiological factors can predict, with relatively good capacity, those more likely to benefit. Clinically, the baseline neurological impairment appears to be strongly related to the outcom…

medicine.medical_specialtyContext (language use)Comorbidity03 medical and health sciencesMyelopathy0302 clinical medicinePhysical medicine and rehabilitationEvoked Potentials SomatosensoryDiabetes MellitusmedicineHumansSpinal cord injurymedicine.diagnostic_testbusiness.industryElectrodiagnosisMental DisordersSmokingPEM PES Electrophysiology MRI DTI FA ADC ImagingMultimodal therapyMagnetic resonance imagingDecompression SurgicalEvoked Potentials MotorPrognosismedicine.diseaseMagnetic Resonance ImagingHyperintensityDiffusion Tensor ImagingSpinal Fusion030220 oncology & carcinogenesisCervical VertebraeSurgerySpondylosisNeurology (clinical)businessSpinal Cord CompressionNeurological impairment030217 neurology & neurosurgeryDiffusion MRI
researchProduct

Mapping and quantification of biomolecules in tumor biopsies using bioluminescence

1996

Quantitative bioluminescence and single-photon imaging have been applied for mapping concentration distributions of metabolites, such as adenosine triphosphate (ATP), glucose and lactate, in biopsies of cervical cancers in patients. Biopsies were taken before a conventional radiation treatment, and a number of clinically relevant data, such as local tumor control, patient survival, metastatic spread and so forth, were documented. There was no correlation between staging or grading and any of the metabolic parameters measured. Local correlations between ATP, glucose and lactate on a pixel-to-pixel basis were generally positive, with respective Spearman's correlation coefficients less in pati…

Pathologymedicine.medical_specialtyBiopsyUterine Cervical NeoplasmsBiologyStatistics NonparametricMetastasisNecrosisCellular and Molecular NeuroscienceAdenosine TriphosphateNeoplasmsmedicineHumansBioluminescenceIn patientNeoplasm MetastasisMolecular BiologyGrading (tumors)Neoplasm StagingPharmacologyMetabolic imagingSingle photon imagingPatient survivalCell Biologymedicine.diseaseTumor controlSurvival RateGlucoseLuminescent MeasurementsLactatesMolecular MedicineFemaleEnergy MetabolismExperientia
researchProduct

"Only Spinal Fixation" as Surgical Treatment of Cervical Myelopathy Related to Ossified Posterior Longitudinal Ligament: Review of 52 Cases.

2020

Background Ossification of the posterior longitudinal ligament (OPLL) is a hyperostotic condition resulting in a progressive narrowing of the spinal canal and subsequent neurologic deficits. Although systemic and local factors in combination with genetic abnormality have been considered in its etiopathogenesis, OPLL remains a poorly understood pathology. Surgical management of OPLL and the choice of the most appropriate treatment are still controversial issues. Here the authors report a series of OPLL-affected patients treated by “only-fixation” technique. Methods Between June 2012 and June 2019, 52 patients having OPLL were treated by a surgical strategy involving only spinal fixation with…

AdultJoint InstabilityMalemedicine.medical_specialtyDecompressionArthrodesismedicine.medical_treatmentOssification of Posterior Longitudinal Ligament03 medical and health sciencesMyelopathyFixation (surgical)0302 clinical medicineSpinal instabilitymedicinePosterior longitudinal ligamentHumansSpinal canalFacetal fixationAtlantoaxial instabilityAgedPain MeasurementNeck Painbusiness.industrySoft tissueMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureSpinal FusionTreatment OutcomeAtlantoaxial instabilityPatient Satisfaction030220 oncology & carcinogenesisCervical VertebraeSurgeryFemaleNeurology (clinical)businessSpinal Cord Compression030217 neurology & neurosurgeryWorld neurosurgery
researchProduct