Search results for "Chela"

showing 10 items of 415 documents

Iron Chelation Therapy in thalassaemia major: a sistematic review with meta-analyses of 1520 patients included on randomized clinical trials

2011

The effectiveness of deferoxamine (DFO), deferiprone (DFP), or deferasirox (DFX) in thalassemia major was assessed. Outcomes were reported as means±SD, mean differences with 95% CI, or standardized mean differences. Statistical heterogeneity was tested using χ2 (Q) and I2. Sources of bias and Grading of Recommendations Assessment, Development and Evaluation system (GRADE) were considered. Overall, 1520 patients were included. Only 7.4% of trials were free of bias. Overall measurements suggest low trial quality (GRADE). The meta-analysis suggests lower final liver iron concentrations during associated versus monotherapy treatment (p<0.0001), increases in serum ferritin levels during DFX 5, 1…

medicine.medical_specialtyPyridonesIronMEDLINEThalassemiaSiderophoresDeferoxamineIron Chelating AgentsChelation treatment thalassaemia clinical trials iron overload meta-analysisBenzoatesGastroenterologylaw.inventionchemistry.chemical_compoundRandomized controlled triallawInternal medicinemedicineHumansVentricular FunctionDeferiproneMolecular BiologyRandomized Controlled Trials as TopicEjection fractionbusiness.industryMyocardiumbeta-ThalassemiaDeferasiroxBeta thalassemiaCell BiologyHematologyTriazolesmedicine.diseaseChelation TherapySurgeryDeferoxamineDeferasiroxTreatment OutcomeLiverchemistryMeta-analysisFerritinsMolecular MedicineDrug Therapy CombinationbusinessDeferipronemedicine.drug
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Maria Michela Sassi (ed.), Tracce nella mente. Teorie della memoria da Platone ai moderni

2009

memoriamenteMaria Michela Sassi
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Changes of several metabolic parameters of soya inoculated with phytopathogens at application nanochelates

2022

n greenhouse experiments changes in several metabolic parameters soybeans plants after inoculation by P. savastanoi pv. glycinea 9190, X. axonopodis pv. glycines 9192, BCMV, A. laidlawii on background pre-treatment by nanochelates (NHs) of V, Ge, Cu, Mo have been shown. The phenolic compounds content increased in leaves at inoculation by phytopathogens on background pre-treatment by NHs and without it. The content of H2O2 in leaves increased in variants: BCMV (+VNHs, GeNHs, CuNHs), 9192 (+VNHs, CuNHs), 9190 (+GeNHs, CuNHs), A. laidlawii+MoNHs. But it decreased in the variants: BCMV + MoNHs, A. laidlawii + VNHs, 9190 + VNHs, 9192 (+ GeNHs, CuNHs) compared to controls. The peroxidase activity…

nanochelatesSoil ScienceForestryPlant ScienceВСMVPseudomonas savastanoi pv. glycineaAgronomy and Crop ScienceNature and Landscape ConservationFood ScienceXantomonas axonopodis pv. glycinesAcholeplasma laidlawii var. granulumAgriculture and Forestry
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« Une altérité novatrice », la notion de « non moi mien » chez Bachelard

2010

International audience

notion[ SHS.PHIL ] Humanities and Social Sciences/Philosophy[SHS.PHIL] Humanities and Social Sciences/Philosophyaltérité novatriceBachelard[SHS.PHIL]Humanities and Social Sciences/Philosophymiennon moiComputingMilieux_MISCELLANEOUS
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Bachelard à l’origine d’une nouvelle philosophie de l’existence ?

2013

International audience

origine[ SHS.PHIL ] Humanities and Social Sciences/Philosophy[SHS.PHIL] Humanities and Social Sciences/PhilosophyBachelardphilosophieexistence[SHS.PHIL]Humanities and Social Sciences/PhilosophyComputingMilieux_MISCELLANEOUS
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Characterization and transcription studies of a phytochelatin synthase gene from the solitary tunicate Ciona intestinalis exposed to cadmium.

2014

The major thiol-containing molecules involved in controlling the level of intracellular ROS in eukaryotes, acting as a nonenzymatic detoxification system, are metallothioneins (MTs), glutathione (GSH) and phytochelatins (PCs). Both MTs and GSH are well-known in the animal kingdom. PC was considered a prerogative of the plant kingdom but, in 2001, a phytochelatin synthase (PCS) gene was described in the nematode Caenorhabditis elegans; additional genes encoding this enzyme were later described in the earthworm Eisenia fetida and in the parasitic nematode Schistosoma mansoni but scanty data are available, up to now, for Deuterostomes. Here, we describe the molecular characteristics and transc…

phytochelatin synthase; Ciona intestinalis; ascidians; cadmium; cell proliferationcadmiumHealth Toxicology and MutagenesisMolecular Sequence DataAquatic ScienceGene Expression Regulation Enzymologicphytochelatin synthaseTranscription (biology)BotanyGene OrderMetallothioneinAnimalsProliferation MarkerCiona intestinalisAmino Acid SequenceGenePhylogenybiologyCell growthGene Expression Profilingbiology.organism_classificationAminoacyltransferasesCell biologyCiona intestinalisascidiansGene expression profilingCionacell proliferationSequence AlignmentWater Pollutants ChemicalCadmiumAquatic toxicology (Amsterdam, Netherlands)
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Complex formation of copper(II) and cadmium(II) with pectin and polygalacturonic acid in aqueous solution. An ISE-H + and ISE-Me 2+ electrochemical s…

2012

The acid-base properties of pectin and its ability to complex with copper(II) or cadmium(II) were quantitatively determined in order to define the ability of this natural polyelectrolyte to sequester metal ions. Potentiometric measurements carried out at different ionic strengths (0.1 - 0.7 mol L-1, in Na+ ionic medium) allowed us to define the acid-base properties of pectin together with the dependence of the protonation constants on ionic strength and to calculate the protonation constant at infinite dilution. The formation of complex species between pectin and copper(II) or cadmium(II) was investigated potentiometrically (using H+, Cu2+ and Cd2+ Ion Selective Electrodes, ISEs) in NaNO3 a…

polysaccharides as chelating agents; metal sequestering ability; complex formation; speciation studiescomplex formationpolysaccharides as chelating agentsSettore CHIM/01 - Chimica Analiticametal sequestering abilitypolysaccharides as chelating agentspeciation studies
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La place et l'influence de l'épistémologie bachelardienne

2009

raisonnement sociologique[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/Lawépistémologie bachelardienne[ SHS.DROIT ] Humanities and Social Sciences/Law
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La Reggia di Venaria Reale in Italy and Palacio Real de Aranjuez in Spain: history, restoration and significance, comparative study between Two Royal…

2017

La investigación relaciona dos sitios reales, La Reggia di Venaria Reale en Italia y el Palacio Real de Aranjuez en España, confrontando su desarrollo histórico y arquitectónico, las obras de restauración llevadas a cabo, los criterios para su inclusión en la Lista de Patrimonio Mundial y su uso hoy en día como museos. El estudio comparativo muestra cómo ambos palacios se usaban inicialmente como residencias de caza en lugares con abundancia de agua y pesca. Además, los dos están ubicados cerca de las capitales políticas de su tiempo; esto es, Turín y Madrid. El hecho que el mismo arquitecto – Filippo Juvarra estuviera presente en ambas residencias reales contribuye a las similitudes, y en …

restorationgiacomo bonaviajuan de villanuevaarquitecturavenaria realepalacio real de madridreggia di venaria realescuderiapatrimonio mundialfrancisco sabatinibenedetto alfierimuseospalacio real de aranjuezpalacio real de la granja de san ildefonsogalleria grandecarlo randonipatrimonio:HISTORIA [UNESCO]santiago bonaviamichelangelo garoveUNESCO::HISTORIAitaliasitios realespatrimonio de la humanidadaranjuezgiuseppe battista piacenzafilippo juvarrajuan bautista de toledoamedeo di castellamonteworld heritage sitescitronierajuan de herrera
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Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

2003

Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…

rho GTP-Binding ProteinsIndolesBacterial ToxinsGlutamic AcidBiologyReceptors Metabotropic GlutamateSulfenic AcidsMaleimidesRats Sprague-DawleyCellular and Molecular NeuroscienceBacterial ProteinsStress FibersmedicinePhospholipase DAnimalsCysteineEgtazic AcidProtein kinase CCells CulturedProtein Kinase CChelating AgentsPharmacologyProtein Synthesis InhibitorsBrefeldin APhospholipase CDose-Response Relationship DrugEndothelin-1Phospholipase DADP-Ribosylation FactorsMetabotropic glutamate receptor 6Glutamate receptorDNAMolecular biologyRatsenzymes and coenzymes (carbohydrates)medicine.anatomical_structureMetabotropic receptorMetabotropic glutamate receptorAstrocytesType C PhospholipasesTetradecanoylphorbol Acetatelipids (amino acids peptides and proteins)AstrocyteNeuropharmacology
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