Search results for "Chemical element"

showing 10 items of 32 documents

The study of neutron-rich nuclei production in the region of the closed shell N=126 in the multi-nucleon transfer reaction 136Xe+208Pb

2015

Expérience LNL/PRISMA; International audience; The unexplored area of heavy neutron rich nuclei is extremely important for nuclearastrophysics investigations and, in particular, for the understanding of the r-process ofastrophysical nucleogenesis. For the production of heavy neutron rich nuclei located along theneutron closed shell N=126 (probably the last "waiting point" in the r-process of nucleosynthesis)the low-energy multi-nucleon transfer reaction 136Xe+208Pb at Elab=870MeV was explored.Due to the stabilizing eect of the closed neutron shells in both nuclei, N=82 and N=126, andthe rather favorable proton transfer from lead to xenon, the light fragments formed in this processare well b…

Historynuclear astro-physicsProtonNuclear Theoryspektrometritchemistry.chemical_element[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciences7. Clean energyEducationNuclear physicsXenonNucleosynthesisneutron-rich nuclei0103 physical sciencesNuclear astrophysicschemical elementsNeutron010306 general physicsNuclear ExperimentOpen shellheavy neutron rich nuclei PRISMA spectrometerPhysicsneutron shellsSpectrometer010308 nuclear & particles physicsbeam linesclosed shellsComputer Science Applicationsneutron beamschemistrytime of flightAtomic physicsNucleon
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Element Inputs by Litterfall to the Soil in Pine Forest Ecosystems

2006

Within the framework of the litterfall chemistry subprogram of the integrated monitoring program, litterfall was collected, and the concentrations of Ca, Mg, K, Pb, and Zn were measured during 1999–2003 at the Taurene and Rucava monitoring stations in Latvia. The results showed that at Rucava there was higher production of litterfall than at Taurene due to a higher tree density. The mean annual litterfall was 3630.42 kg/ha−1 in Rucava and 3022.11 kg/ha−1 in Taurene, with maximum production in autumn at both sites. The litterfall production among the catchments varied seasonally because length of growing period, composition of tree species, and density of snow cover. The higher Ca, Mg, and K…

Hydrologygeographygeography.geographical_feature_categoryEcologyEcologyDrainage basinAir pollutionPlant litterChemical elementmedicine.disease_causeNutrientLittermedicineEnvironmental scienceEcosystemComposition (visual arts)Ecology Evolution Behavior and SystematicsEnvironmental Bioindicators
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A new insight into the three-dimensional architecture of the Golgi complex: Characterization of unusual structures in epididymal principal cells.

2017

Principal epididymal cells have one of the largest and more developed Golgi complex of mammalian cells. In the present study, we have used this cell as model for the study of the three-dimensional architecture of the Golgi complex of highly secretory and endocytic cells. Electron tomography demonstrated the presence in this cell type of some unknown or very unusual Golgi structures such as branched cisternae, pocket-like cisternal invaginations or tubular connections. In addition, we have used this methodology and immunoelectron microscopy to analyze the close relationship between this organelle and both the endoplasmic reticulum and microtubules, and to describe in detail how these element…

Male0301 basic medicineEndocytic cycleGolgi Apparatuslcsh:MedicineEndoplasmic ReticulumMicrotubulesDiagnostic RadiologyRats Sprague-Dawley0302 clinical medicineMedicine and Health Scienceslcsh:ScienceTomographyCytoskeletonEpididymisSecretory PathwayMultidisciplinaryChemistryRadiology and ImagingCell biologyChemistryCell ProcessesPhysical SciencessymbolsCellular Structures and OrganellesAnatomyGenital AnatomyResearch ArticleChemical ElementsCell typeImaging TechniquesImmunoelectron microscopyResearch and Analysis Methods03 medical and health sciencessymbols.namesakeDiagnostic MedicineMicrotubuleOrganelleAnimalsVesiclesEndoplasmic reticulumlcsh:RReproductive SystemBiology and Life SciencesCell BiologyGolgi apparatusMicroscopy Electron030104 developmental biologyElectron tomographylcsh:Q030217 neurology & neurosurgeryPLoS ONE
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Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching

2017

Introduction Current treatment with vasodilators for pulmonary hypertension associated with respiratory diseases is limited by their inhibitory effect on hypoxic pulmonary vasoconstriction (HPV) and uncoupling effects on ventilation-perfusion (V'/Q'). Hypoxia is also a well-known modulator of the nitric oxide (NO) pathway, and may therefore differentially affect the responses to phosphodiesterase 5 (PDE5) inhibitors and soluble guanylyl cyclase (sGC) stimulators. So far, the effects of the sGC stimulator riociguat on HPV have been poorly characterized. Materials and methods Contraction was recorded in pulmonary arteries (PA) in a wire myograph. Anesthetized rats were catheterized to record …

MaleAnoxemiaPulmonologyPulmonary FibrosisVasodilator Agentslcsh:MedicineVasodilation030204 cardiovascular system & hematologyPharmacologyVascular Medicinechemistry.chemical_compound0302 clinical medicineSoluble Guanylyl CyclaseHypoxic pulmonary vasoconstrictionPulmonary fibrosisMedicine and Health SciencesPulmonary Arterieslcsh:ScienceHypoxiaMultidisciplinaryVasodilatorsDrugsRespiratory organs diseasesArteriesMiddle AgedChemistryPhysical Sciencescardiovascular systemFemalemedicine.symptomAnatomyMedicamentsmedicine.drugResearch ArticleChemical Elementsinorganic chemicalsSildenafilHypertension PulmonaryChronic Obstructive Pulmonary DiseaseEnzyme ActivatorsIn Vitro TechniquesPulmonary ArteryRiociguatSildenafil CitrateMalalties de l'aparell respiratori03 medical and health sciencesMedical HypoxiamedicineVentilation-Perfusion RatioAnimalsHumansRats WistarAgedPharmacologybusiness.industrylcsh:RAnoxèmiaBiology and Life SciencesHypoxia (medical)Phosphodiesterase 5 Inhibitorsmedicine.diseasePulmonary hypertensionFibrosisRatsOxygenDisease Models AnimalPyrimidines030228 respiratory systemchemistryVasoconstrictionCardiovascular AnatomyPyrazolesBlood Vesselslcsh:QSoluble guanylyl cyclasebusinessDevelopmental Biology
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Criteria for the determination of maximal oxygen uptake in patients newly diagnosed with cancer : Baseline data from the randomized controlled trial …

2020

IntroductionMaximal oxygen uptake ([Formula: see text]) is a measure of cardiorespiratory fitness often used to monitor changes in fitness during and after treatment in cancer patients. There is, however, limited knowledge in how criteria verifying [Formula: see text] work for patients newly diagnosed with cancer. Therefore, the aim of this study was to describe the prevalence of fulfillment of typical criteria verifying [Formula: see text] and to investigate the associations between the criteria and the test leader's evaluation whether a test was performed "to exhaustion". An additional aim was to establish new cut-points within the associated criteria.MethodsFrom the Phys-Can randomized c…

MaleCancer Treatmentlaw.inventionCohort Studies0302 clinical medicineRandomized controlled trialHeart RateReference ValueslawNeoplasmsMedicine and Health SciencesPublic and Occupational HealthTreadmillRespiratory exchange ratioRating of perceived exertioneducation.field_of_studyMultidisciplinaryQRVO2 maxMiddle AgedVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Sports ScienceExercise TherapyChemistryTreatment OutcomeOncologyCardiorespiratory FitnessResearch Design030220 oncology & carcinogenesisPhysical SciencesMedicineFemaleResearch ArticleChemical Elementsmedicine.medical_specialtySciencePhysical ExertionPopulationCardiologyResearch and Analysis Methods03 medical and health sciencesOxygen ConsumptionDiagnostic MedicineInternal medicineHeart rateCancer Detection and DiagnosismedicineHumansSports and Exercise MedicineeducationExerciseAgedColorectal Cancerbusiness.industryBiology and Life SciencesCancers and NeoplasmsCardiorespiratory fitnessPhysical Activity030229 sport sciencesOxygenROC CurvePhysical FitnessExercise Testbusinesshuman activities
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Early improvement of executive test performance during antidepressant treatment predicts treatment outcome in patients with Major Depressive Disorder

2017

Executive dysfunctions frequently occur in patients with Major Depressive Disorder and have been shown to improve during effective antidepressant treatment. However, the time course of improvement and its relationship to treatment outcome is unknown. The aim of the study was to assess the test performance and clinical outcome by repetitive assessments of executive test procedures during antidepressant treatment. Executive test performance was assessed in 209 –patients with Major Depressive Disorder (mean age 39.3 ± 11.4 years) and 84 healthy controls five times in biweekly intervals from baseline to week 8. Patients were treated by a defined treatment algorithm within the early medication c…

Malelcsh:MedicineSocial SciencesNeuropsychological TestsSeverity of Illness IndexExecutive FunctionCognition0302 clinical medicineMedicine and Health SciencesPsychologyVerbal fluency testlcsh:ScienceProspective cohort studyDepression (differential diagnoses)Cognitive ImpairmentMultidisciplinaryDepressionCognitive NeurologyPharmaceuticsCognitive flexibilityDrugsCognitionAntidepressantsMiddle AgedAntidepressive AgentsCognitive LinguisticsChemistryTreatment OutcomeNeurologyPhysical SciencesMajor depressive disorderFemaleResearch ArticleChemical ElementsAdultmedicine.medical_specialtyCognitive NeuroscienceLithium03 medical and health sciencesDrug TherapyNeuropsychologyRating scaleMental Health and PsychiatrySeverity of illnessmedicineHumansNeuropsychological TestingPharmacologyDepressive Disorder MajorMood Disordersbusiness.industrylcsh:RBiology and Life SciencesLinguisticsmedicine.disease030227 psychiatryCase-Control StudiesPhysical therapyCognitive Sciencelcsh:QbusinessPsychomotor Performance030217 neurology & neurosurgeryNeurosciencePLOS ONE
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Heavy Metals in Mollusc Shells: A Quick Method for their Detection

2015

It is known for a long time that calcified tissues secreted by aquatic or terrestrial invertebrates – such as mollusc shells – have the ability to concentrate large amounts of pollutants, in particular heavy metals. In the present paper, we have found an extremely rapid and easy procedure to qualitatively detect the putative presence of heavy metals in shells, without having to use sophisticated techniques such as Wavelength Dispersive Spectroscopy, atomic adsorption spectroscopy or ICP-MS. Our method rests on the capacity of the silver enhancement chemicals that are traditionally used in immunogold localization experiments to increase the size of heavy metal nanoparticles, whatever the che…

Materials scienceScanning electron microscope0211 other engineering and technologiesAnalytical chemistry[ SDV.TOX.ECO ] Life Sciences [q-bio]/Toxicology/EcotoxicologyNanoparticle020101 civil engineering02 engineering and technologyChemical element0201 civil engineeringMetalAdsorptionWavelength-dispersive X-ray spectroscopy[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]021105 building & constructionGeneral Materials ScienceSpectroscopyComputingMilieux_MISCELLANEOUS[SDV.TOX.ECO] Life Sciences [q-bio]/Toxicology/EcotoxicologyMechanical EngineeringHeavy metals[ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]13. Climate actionMechanics of Materialsvisual_artvisual_art.visual_art_medium[SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN][SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/EcotoxicologyKey Engineering Materials
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Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: a QM/MM study

2019

AbstractCyclin-dependent kinase 2 (CDK2) is an important member of the CDK family exerting its most important function in the regulation of the cell cycle. It catalyzes the transfer of the gamma phosphate group from an ATP (adenosine triphosphate) molecule to a Serine/Threonine residue of a peptide substrate. Due to the importance of this enzyme, and protein kinases in general, a detailed understanding of the reaction mechanism is desired. Thus, in this work the phosphoryl transfer reaction catalyzed by CDK2 was revisited and studied by means of hybrid quantum mechanics/molecular mechanics (QM/MM) calculations. Our results show that the base-assisted mechanism is preferred over the substrat…

Models MolecularComposite ParticlesProtein ConformationPhysical ChemistryBiochemistry01 natural sciencesSubstrate Specificitychemistry.chemical_compoundPhosphorylationPost-Translational ModificationFree Energy0303 health sciencesMultidisciplinarybiologyKinasePhysicsQChemical ReactionsRChemistryReaction DynamicsPhysical SciencesThermodynamicsMedicineProtonsResearch ArticleChemical ElementsAtomsStereochemistryScienceMolecular Dynamics Simulation010402 general chemistryMolecular mechanicsReactantsQM/MMStructure-Activity Relationship03 medical and health sciencesCyclin-dependent kinaseParticle PhysicsNuclear PhysicsNucleons030304 developmental biologyChemical BondingCyclin-Dependent Kinase 2Cyclin-dependent kinase 2Biology and Life SciencesProteinsActive siteHydrogen BondingTransition StateBond order0104 chemical sciencesOxygenModels Chemicalchemistrybiology.proteinQuantum TheoryAdenosine triphosphate
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The Evolution of Individuality at the Molecular and Protocellular Levels

1984

The most important bioelements (= organoelements) hydrogen, carbon, oxygen and nitrogen, are also the most abundant elements throughout the Universe besides helium, neon, and silicon (Fig, 1). In the Universe carbon is about four times as abundant as silicon. Certainly, the abundance of elements in various celestial bodies may vary greatly depending on the history of these celestial bodies.

NeonchemistrySiliconHydrogenCarbonaceous chondritechemistry.chemical_elementNitrogenCarbonHeliumAbundance of the chemical elementsAstrobiology
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Usual Care and Informed Consent in Clinical Trials of Oxygen Management in Extremely Premature Infants

2016

Objective The adequacy of informed consent in the Surfactant, Positive Pressure, and Pulse Oximetry Randomized Trial (SUPPORT) has been questioned. SUPPORT investigators and publishing editors, heads of government study funding agencies, and many ethicists have argued that informed consent was adequate because the two oxygen saturation target ranges studied fell within a range commonly recommended in guidelines. We sought to determine whether each oxygen target as studied in SUPPORT and four similar randomized controlled trials (RCTs) was consistent with usual care. Design/Participants/Setting PubMed, EMBASE, Web of Science, and Scopus were searched for English articles back to 1990 providi…

PediatricsComparative Effectiveness ResearchAlternative medicinePsychological interventionlcsh:MedicineNeonatal Carelaw.inventionDatabase and Informatics Methods0302 clinical medicineRandomized controlled triallawInformed consentMedicine and Health Sciences030212 general & internal medicineOximetryDatabase Searchinglcsh:ScienceRandomized Controlled Trials as TopicMultidisciplinarymedicine.diagnostic_testHospitalsInformed Consent By MinorsChemistryIntensive Care UnitsResearch DesignInfant Extremely PrematurePhysical SciencesResearch ArticleChemical ElementsAdultmedicine.medical_specialtyDrug Research and DevelopmentClinical Research DesignDeath RatesComparative effectiveness researchResearch and Analysis Methods03 medical and health sciencesPopulation Metrics030225 pediatricsmedicineHumansClinical TrialsIntensive care medicineOxygen saturationDemographyPharmacologyPopulation Biologybusiness.industrylcsh:RInfant NewbornBiology and Life SciencesRandomized Controlled TrialsClinical trialOxygenHealth CarePulse oximetryHealth Care FacilitiesPeople and PlacesIntensive Care Neonatallcsh:QClinical MedicinebusinessPLoS ONE
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