Search results for "Chemosensor"

Perception des molécules chimiosensorielles en mélange : impact du métabolisme périphérique

2015

The chemosensory system is highly sensitive and discriminant. To ensure these properties, rapid and effective mechanisms are necessary to eliminate chemosensory molecules reaching the perception interface. The xenobiotic metabolizing enzymes (XMEs) present in the peri-receptor space may participate to the clearance of molecules thus limiting chemosensory receptors saturation and promoting the termination of the signal. In our PhD thesis, the involvement of these enzymes in the detection of stimuli in mixture was assessed in two animal models allowing to test complementary aspects. In Drosophila melanogaster, a sensory exposure to caffeine causes a reversible alteration of the taste percepti…

Troubles du goût et de l'odorat chez les seniors

2022

First Chemosensor for Selective Detection and Quantification of L-4-Hydroxyproline in Collagen and Other Bio Samples.

2017

Amino pyridine-based rhodamine conjugate (APR) has been developed as a first chemosensor for selective detection and quantification of L-4-Hydroxyproline (Hyp). The “turn-on” fluorescence property of the chemosensor makes it unique for easy estimation of Hyp in collagen and biological samples. peerReviewed

Goût et préférences du consommateur âgé

2017

Revue; Goût et préférences du consommateur âgé. Sixième journée mondiale de la déglutition :

Current Status on the Functional Characterization of Chemosensory Receptors of Cydia pomonella (Lepidoptera: Tortricidae)

2018

Cydia pomonella (Lepidoptera: Tortricidae) is a major pest of apple, pear and walnuts. For its control, alternative strategies targeting the olfactory system, like mating disruption, have been combined with insecticide applications. The efficacy of these strategies headed the direction of efforts for the functional characterization of codling moth chemosensory receptors to implement further control methods based on chemical sensing. With the advent of transcriptomic analysis, partial and full-length coding sequences of chemosensory receptors have been identified in antennal transcriptomes of C. pomonella. Extension of partial coding sequences to full-length by polymerase chain reaction (PCR…

An Off-On-Off Fluorescent Sensor for pH Windows Based on the 13aneN4-Zn 2+ System

2016

International audience; The new ligand L was prepared and features a 13-membered tetraaza macrocyclic ring with a 1,8-naphthalimide fluorophore appended to a C atom of its backbone. The protonation constants of L as well as its complexation constants with Zn2+ ions were determined in 1:1 water/methanol solutions by potentiometric titrations. Fluorimetric pH titrations were performed with L alone and L in the presence of Zn2+ ions (1:1), and the species distributions (%) versus pH were compared. A window-shaped fluorescence trend was observed with pH for the L/Zn2+ system, which behaves as an off-on-off pH sensor. The on window is centred in the 6.5-7.5 pH range, in correspondence with the f…

Amygdaloid projections to the ventral striatum in mice: direct and indirect chemosensory inputs to the brain reward system

2011

Rodents constitute good models for studying the neural basis of socio-sexual behaviour. Recent findings in mice have revealed the molecular identity of the some pheromonal molecules triggering intersexual attraction. However, the neural pathways mediating this basic socio-sexual behaviour remain elusive. Since previous work indicates that the dopaminergic tegmento-striatal pathway is not involved in pheromone reward, the present report explores alternative pathways linking the vomeronasal system with the tegmento-striatal system (the limbic basal ganglia) by means of tract-tracing experiments studying direct and indirect projections from the chemosensory amygdala to the ventral striato-pall…

Latest insight into factors that affect food perception in older adults

2016

Revue; Latest insight into factors that affect food perception in older adults. Food Matters Live: Meeting the sensory capabilities of the older consumer

The effectiveness of personalized design to feed elderly people

2015

Beyond the physiological age, the elderly population is characterized by a high heterogeneity in terms of physical, psychological and sociological status (Maître et al, 2015). Regarding eating behavior, several studies have highlighted a large inter-individual variability in chemosensory abilities (i.e. the ability to perceive an odor or a taste; Sulmont-Rossé et al, 2015) and oral-heath status (i.e. dental status, salivary flow; ALIMASSENS project), as well as inter-individual variability in food preference and food intake (AUPALESENS project). However, the food offer dedicated to the elderly population, and in particular to elderly people who needs help to obtain and/or prepare food for t…

Chemosensory reactivity and food neophobia in preschool children: impact of smell, but not of taste

2014

Context and objective: Recent studies suggested that sensory sensitivity could be linked to food neophobia, described as the reluctance to eat, or the avoidance of, new foods. The objective of the present study was twofold. Firstly, this study aimed at assessing the links between smell reactivity and taste reactivity in children. Secondly, this study assessed the links between children’s smell/taste reactivity and food neophobia. The hypothesis was that the higher the chemosensory reactivity of the child, the more the child is neophobic. Method: One hundred and three dyads of mother-child, from the Opaline cohort, were involved. The child’s food neophobia was assessed using a validated pare…