Search results for "Chest"

showing 10 items of 302 documents

Thrombolysis plus heparin versus heparin alone in the acute phases of unstable angina: preliminary findings

1995

Abstract Several studies have shown conflicting effects of thrombolysis in patients with unstable angina. In these trials the time between presentation with chest pain and randomization was long (12 hours to 3 days). This study compared thrombolysis and heparin with heparin-alone treatment in patients in the acute phase of unstable angina. One hundred fifty-three consecutive patients hospitalized with chest pain at rest (first episode) lasting >5 minutes but P = 0.013). Data suggest that thrombolysis plus heparin produces faster clinical stabilization than heparin alone in patients treated during the acute phase of unstable angina.

PharmacologyFirst episodemedicine.medical_specialtyRandomizationT-plasminogen activatorbusiness.industrymedicine.drug_classUnstable anginamedicine.medical_treatmentAnticoagulantHeparinThrombolysisChest painmedicine.diseaseSurgeryAnesthesiamedicinePharmacology (medical)medicine.symptombusinessmedicine.drugCurrent Therapeutic Research
researchProduct

Pneumonia hospitalizations of children aged <2 years in Poland before (2013-2016) and after (2017-2018) universal mass vaccination with 10-valent pne…

2022

As infection with Streptococcus pneumoniae is an important cause of pneumonia in children, the World Health Organization recommends childhood pneumococcal conjugate vaccines (PCVs). In January 2017, PCV universal mass vaccination (UMV) was introduced in Poland for children aged <2 years. The objective of this study was to estimate and describe the trends in the incidences of various types of pneumonia hospitalizations in Poland before (2013–2016) and after (2017–2018) introduction of the UMV program. The study was conducted at the regional hospitals of Opole and Bialystok and included all hospitalized children aged <2 years with a primary or secondary diagnosis of pneumonia in their electro…

PharmacologyImmunologyImmunology and AllergyPneumonia; pneumococcal conjugate vaccine; PHiD-CV; universal mass vaccination; Poland; incidence; chest radiograph; ICD-10Human Vaccines & Immunotherapeutics
researchProduct

Shape coexistence in Hg-178

2019

Lifetime measurements of excited states in Hg-178 have been performed using the Rh-103(Kr-78, p2n) reaction at a beam energy of 354 MeV. The recoil-decay tagging (RDT) technique was applied to select the Hg-178 nuclei and associate the prompt gamma rays with the correlated characteristic ground-state alpha decay. Lifetimes of the four lowest yrast states of Hg-178 have been determined using the recoil distance Doppler-shift (RDDS) method. The experimental data are compared to theoretical predictions with focus on shape coexistence. The results confirm the shift of the deformed prolate structures to higher lying states but also indicate their increasing deformation with decreasing neutron nu…

PhysicsGEManchester Cancer Research Centre3106010308 nuclear & particles physicsYrastResearchInstitutes_Networks_Beacons/mcrcNuclear structureProlate spheroidNuclear Structure01 natural sciences114 Physical sciencesLIFETIMESPLUNGERRecoilSTATESExcited stateNeutron number0103 physical sciencesMERCURYAtomic physics010306 general physicsNuclear ExperimentBeam energy
researchProduct

Lifetime measurements in 166Re : Collective versus magnetic rotation

2016

WOS: 000371740600004

PhysicsManchester Cancer Research Centreta114010308 nuclear & particles physicsResearchInstitutes_Networks_Beacons/mcrcMagnetic rotationRouthianNuclear TheoryOrder (ring theory)Semiclassical physicsState (functional analysis)rhenium01 natural sciencesNuclear shapeRecoilExcited state0103 physical scienceslifetimesAtomic physics010306 general physicsexcited statesPhysical Review C
researchProduct

TPEN: A Triple-foil differential Plunger for lifetime measurements of excited states in Exotic Nuclei

2019

Abstract A Triple-foil differential Plunger for Exotic Nuclei (TPEN) has been developed to measure the lifetimes of excited states in nuclei with small production cross-sections. TPEN utilises one target foil and two degrader foils to make differential lifetime measurements: directly determining the decay function and its derivative at a single plunger distance setting. The direct measurement of the decay function and its derivative removes the requirement to measure γ -ray intensities at several target-to-degrader distances, thereby reducing the beam-time required relative to a conventional plunger with a single-degrader foil. This paper describes the commissioning of TPEN in the lifetime …

PlungerPhysicsNuclear and High Energy PhysicsDDCMManchester Cancer Research Centreta114ResearchInstitutes_Networks_Beacons/mcrctutkimuslaitteet156Dyplungerexcited-state lifetimestriple-foil plungerRDDSDecay functionExcited stateAtomic physicsydinfysiikkaInstrumentationFOIL method
researchProduct

The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN

2022

Primary ciliary dyskinesia; Rare genetic disorder; Lung diseases Discinesia ciliar primaria; Trastorno genético raro; Enfermedades pulmonares Discinesia ciliar primària; Trastorn genètic rar; Malalties pulmonars Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by impaired mucociliary clearance leading to irreversible lung damage. In contrast to other rare lung diseases like cystic fibrosis (CF), there are only few clinical trials and limited evidence-based treatments. Management is mainly based on expert opinions and treatment is challenging due to a wide range of clinical manifestations and disease severity. To improve clinical and translational research and facili…

Pulmonary and Respiratory Medicine:enfermedades respiratorias::trastornos de la motilidad ciliar [ENFERMEDADES]:Health Occupations::Medicine::Pediatrics [DISCIPLINES AND OCCUPATIONS]Respiratory SystemSağlık BilimleriClinical Medicine (MED)SOLUNUM SİSTEMİRespiratory CareHealth SciencesMANAGEMENTKlinik Tıp (MED)Chest Diseases and Allergy:profesiones sanitarias::medicina::pediatría [DISCIPLINAS Y OCUPACIONES]:Otros calificadores::/terapia [Otros calificadores]:Respiratory Tract Diseases::Ciliary Motility Disorders [DISEASES]Internal Medicine SciencesScience & TechnologyKlinik TıpMUTATIONSRESPIRATORY SYSTEM:Other subheadings::/therapy [Other subheadings]Dahili Tıp BilimleriGöğüs Hastalıkları ve AllerjiCLINICAL MEDICINECèl·lules - Motilitat:Congenital Hereditary and Neonatal Diseases and Abnormalities::Genetic Diseases Inborn [DISEASES]TıpPulmons - Malalties - TractamentAkciğer ve Solunum TıbbıMedicineMalalties congènites:enfermedades y anomalías neonatales congénitas y hereditarias::enfermedades genéticas congénitas [ENFERMEDADES]Solunum BakımıLife Sciences & BiomedicinePulmons Malalties
researchProduct

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE)

2023

Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventila…

Pulmonary and Respiratory MedicineInternal Medicine SciencesKlinik TıpRESPIRATORY SYSTEMDahili Tıp BilimleriGöğüs Hastalıkları ve AllerjiCLINICAL MEDICINESağlık BilimleriClinical Medicine (MED)TıpSOLUNUM SİSTEMİMechanical ventilationN/AHealth SciencesSettore MED/41 - ANESTESIOLOGIAAkciğer ve Solunum TıbbıMedicineKlinik Tıp (MED)Chest Diseases and AllergyThe Lancet Respiratory Medicine
researchProduct

Against all odds: anti-IgE for intrinsic asthma?

2013

For many years, pathogenetic concepts and the results of clinical trials supported the view that anti-IgE treatment is specifically effective in allergic asthma. However, there is now growing clinical and mechanistic evidence suggesting that treatment with the anti-IgE antibody omalizumab can be effective in patients with intrinsic asthma. Therefore, large and well-controlled clinical trials with anti-IgE are urgently warranted in patients with intrinsic asthma. In addition, there is a need to find new biomarkers which can identify patients with asthma who respond to anti-IgE treatment.

Pulmonary and Respiratory MedicineIntrinsic FactorChest ClinicOmalizumabOmalizumabAsthma PharmacologyImmunoglobulin EAntibodies Monoclonal HumanizedAnti-asthmatic AgentOddsmedicineHumansAnti-Asthmatic Agents1506AsthmaIntrinsic factorbiologybusiness.industrymedicine.diseaseAsthmaImmunity Innaterespiratory tract diseasesAntibodies Anti-IdiotypicClinical trialAsthma MechanismsIntrinsic asthmaImmunologybiology.proteinDisease Progressionbusinessmedicine.drugThorax
researchProduct

Physical exercise and Sport activities in patients with and without coronary heart disease

2016

Background: The quantity and intensity of physical activity required for the primary prevention of coronary heart disease remain unclear. Therefore, we examined the association between physical activity and coronary risk. Methods: We studied 100 patients with chest pain, 78 men and 22 women, not older than 65 years, admitted to a coronary care unit. Patients were subdivided in 3 groups: the first group included patients with acute myocardial infarction, the second group included patients with chronic heart disease, the third included patients with non-ischemic chest-pain. A questionnaire on daily physical activity was filled by each patient. Results: A significantly higher percentage of pat…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyHeart diseaselcsh:MedicinePhysical exerciseCoronary DiseaseChest painRisk AssessmentmedicineHumansMyocardial infarctioncoronary heart diseaseFramingham Risk Scoreexercisebusiness.industrylcsh:Rmedicine.diseaseCoronary heart diseasemyocardial infarctionCoronary care unitPhysical therapyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessRisk assessmentsportSportsMonaldi Archives for Chest Disease
researchProduct

Secondary Carina and Lobar Bronchi Stenting in Patients with Advanced Lung Cancer: Is It Worth the Effort? A Clinical Experience

2020

Background: The lobar airway stenting remains an endoscopic procedure not well standardized in patients with locally advanced lung cancer disease. The goal of this study was to evaluate technical feasibility, clinical outcome, and complications of different stents in patients with malignant lesions involving lobar bronchi, primary and secondary carina. Methods: Between November 2008 and October 2013, we retrospectively analyzed 146 patients with benign and malignant tracheobronchial stenosis who underwent airway stent insertion below main carina and main bronchi. Results: In all, 170 airway stenting procedures were performed on 146 patients. In all, 51 of them with malignant peripheral airw…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentSettore MED/21 - Chirurgia ToracicaBronchiairway stentingBronchoscopymedicineHumansIn patientLung cancerAgedRetrospective StudiesAged 80 and overLungmedicine.diagnostic_testbusiness.industryPalliative CareGastroenterologyStentGranulation tissueGeneral Medicinerespiratory systemMiddle Agedmedicine.diseaseequipment and suppliesrespiratory tract diseasesAirway ObstructionStenosislung cancermedicine.anatomical_structureTreatment Outcomeairway stenosisFeasibility StudiesSurgeryFemaleStentsOriginal ArticleRadiologyCardiology and Cardiovascular MedicineAirwayChest radiographbusinessTracheal Stenosis
researchProduct