Search results for "Children"

showing 10 items of 1661 documents

A Cohort Study of Childhood Cancer Incidence after Postnatal Diagnostic X-Ray Exposure

2009

Ionizing radiation is an established cause of cancer, yet little is known about the health effects of doses from diagnostic examinations in children. The risk of childhood cancer was studied in a cohort of 92.957 children who had been examined with diagnostic X rays in a large German hospital during 1976-2003. Radiation doses were reconstructed using the individual dose area product and other exposure parameters, together with conversion coefficients developed specifically for the medical devices and standards used at the radiology department. Newly diagnosed cancers occurring between 1980 and 2006 were determined through record linkage to the German Childhood Cancer Registry. The median ra…

AdultMalemedicine.medical_specialtyPediatricsNeoplasms Radiation-InducedAdolescentBiophysicsCohort StudiesGermanyNeoplasmsRadiation IonizingEpidemiologymedicineHumansRadiology Nuclear Medicine and imagingRegistriesChildChildhood Cancer RegistryRadiationbusiness.industryIncidenceX-RaysIncidence (epidemiology)InfantCancermedicine.diseaseLeukemia2nd malignant neoplasms; ionizing-radiation; computed-tomography; ultrasound exposure; young-children; risk-factors; in-utero; survivors; leukemia; irradiationChild PreschoolMultivariate AnalysisCohortFemalebusinessRecord linkageCohort studyRadiation Research
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The Use of Lower or Higher Than Recommended Doses of Folic Acid Supplements during Pregnancy Is Associated with Child Attentional Dysfunction at 4–5 …

2021

We assessed the association between the use of lower- and higher-than-recommended doses of folic acid supplements (FAs) during pregnancy and attentional function in boys and girls at age of 4–5. We analyzed data from 1329 mother-child pairs from the mother-child cohort INfancia y Medio Ambiente Project (INMA) study. Information on FAs use during pregnancy was collected in personal interviews at weeks 12 and 30, and categorized in &lt

AdultMalemedicine.medical_specialtylcsh:TX341-641030209 endocrinology & metabolismNeuropsychological TestsArticle03 medical and health sciencesfolic acidChild Development0302 clinical medicinechildrenSupplement useHumansMedicineAttentionProspective Studiessupplement useattentional functionPregnancyNutrition and Dieteticsneurodevelopmentbusiness.industryObstetricsmedicine.diseaseConfidence interval3. Good healthStandard errorFolic acidSpainChild PreschoolPrenatal Exposure Delayed EffectsDietary SupplementsCohortLinear ModelsFemalepregnancybusinesslcsh:Nutrition. Foods and food supply030217 neurology & neurosurgeryFood ScienceNutrients
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Double-blind, randomized, placebo-controlled trial of allergen-specific immunotherapy with the major allergen Alt a1

2019

Background: There have been few studies conducted on the efficacy and safety of specific immunotherapy with allergen extracts of fungi compared with other allergen extracts, and there are no data on the major allergen Alt a 1 of the fungus Alternaria alternata. Objectives: We sought to evaluate the efficacy and safety of subcutaneous immunotherapy with 2 different doses of Alt a 1 in patients with rhinoconjunctivitis caused by sensitization to A alternata. Method: We performed a multicenter, randomized, double-blind, placebo-controlled trial with Alt a 1 administered subcutaneously in patients with allergic rhinoconjunctivitis with or without controlled asthma aged 12 to 65 years. Three gro…

AdultMalesafetyAllergymedicine.medical_specialtyAllergen immunotherapyAl·lèrgiaAdolescentImmunologyefficacyPlacebo-controlled studyPlacebomedicine.disease_causeFungal ProteinsYoung AdultAllergenDouble-Blind Methodchildrensubcutaneous immunotherapyInternal medicinemedicineadultsImmunology and AllergyHumansmolecular immunotherapyAdverse effectChildAgedConjunctivitis AllergicAllergen immunotherapyIntention-to-treat analysisbusiness.industryrhinoconjunctivitisclinical trialAllergensImmunoglobulin EMiddle Agedmedicine.diseaseAsthmaClinical trialfungal allergyDesensitization ImmunologicImmunoglobulin GAlt a 1Femalebusinesspurified allergen
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The reliability of measuring medial gastrocnemius muscle-tendon unit lengths during gait

2021

Background Ultrasound imaging combined with 3D motion analysis allows for in-vivo assessment of muscle-tendon unit lengths during gait. The clinical relevance of analysing the medial gastrocnemius (MG) and Achilles muscle-tendon junction (MTJ), MG mid-muscle belly fascicles (FAS) and muscle thickness was shown. However, their reliability error estimations over the gait cycle is unknown. Research question What are the intra- and inter-session errors associated with extracting MG belly, thickness, FAS and tendon lengths using ultrasound during gait in healthy participants? Methods 3D gait analysis was carried out in ten healthy adults as they walked on an instrumented treadmill at a comfortab…

AdultMedial gastrocnemiusBiophysicslihaksetCHILDRENWalkingAchilles TendonStandard deviationjänteetGait (human)Dynamic ultrasoundMedicine and Health SciencesHumansMedicineOrthopedics and Sports MedicineliikeanalyysiLower limb muscle-tendonMuscle SkeletalGaitReliability (statistics)Ultrasonographyreliabiliteettibusiness.industryUltrasoundRehabilitationReproducibility of ResultsReliabilityjalatTendonkävelymittausmenetelmätPreferred walking speedmedicine.anatomical_structureGait analysisaskeleetultraäänitutkimusGait analysisbiomekaniikkabusinessWALKINGBiomedical engineering
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Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults

2021

ABSTRACTObjectivesThere is limited information comparing SARS-CoV-2 RNA load in the upper respiratory tract (URT) between children and adults, either presenting with COVID-19 or asymptomatic. Here we conducted a retrospective, single center study involving a large cohort of SARS-CoV-2 infected individuals to address this issue.Patients and MethodsA total of 1,184 consecutive subjects (256 children and 928 adults) testing positive for SARS-COV-2 RNA in nasopharyngeal exudates (NP) were included, of whom 424 (121 children and 303 adults) had COVID-19 not requiring hospitalization and 760 (135 children and 625 adults) were asymptomatic close contacts of COVID-19 patients. SARS-CoV-2 RNA testin…

AdultMicrobiology (medical)medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationSingle CenterAsymptomaticGastroenterologychildrenNasopharynxInternal medicinemedicineSingle specimenAdultsHumansViral sheddingChildeducationAsymptomatic InfectionsRetrospective Studieseducation.field_of_studySARS-CoV-2business.industryCOVID-19RNAGeneral MedicineViral LoadSARS-CoV-2 RNALarge cohortInfectious Diseasesmedicine.anatomical_structureRNA ViralOriginal Articlemedicine.symptombusinessViral loadUpper respiratory tractRespiratory tractClinical Microbiology and Infection
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Assessment of Referees in Terms of Building a Positive Climate and Responsiveness to the Health, Emotional, and Social Needs of Rugby Players in Comp…

2021

One of the key elements of effective sports programs that contribute to a child’s sense of joy and satisfaction in participating in sports is contact with an adult who builds a caring climate deliberately and intentionally. Referees play a special role in providing positive experiences for young athletes. The main aim of this study was to assess the quality of referee–player interactions in terms of building a positive climate during the game and the referee’s responsiveness to the health, emotional, social, and cognitive needs of young rugby players aged 6–12 years. The research was conducted among 23 referees refereeing children’s rugby matches in Poland. The structure observation method …

AdultNeed for cognitionWilcoxon signed-rank testpositive climateHealth Toxicology and Mutagenesismedia_common.quotation_subjectEmotionsApplied psychologyFootballrefereeArticleHumansQuality (business)rugbyChildmedia_commonbiologyAthletesYouth SportsPublic Health Environmental and Occupational Healthchildren sportReducational practiceCognitionbiology.organism_classificationTest (assessment)AthletesScale (social sciences)MedicineJob satisfactionPolandPsychologysport officialInternational Journal of Environmental Research and Public Health
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Effect of childhood developmental coordination disorder on adulthood physical activity; Arvo Ylppö longitudinal study

2022

Publisher Copyright: © 2022 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd. Individuals at risk of Developmental Coordination Disorder (DCD) have low levels of physical activity in childhood due to impaired motor competence; however, physical activity levels in adulthood have not been established. This study sought to determine the impact of DCD risk on physical activity levels in adults using accelerometry measurement. Participants (n = 656) from the Arvo Ylppö Longitudinal Study cohort had their motor competence assessed at the age of five years, and their physical activity quantified via device assessment at the age of 25 years. Betwe…

Adultkoordinaatio (motoriikka)FITNESSPARTICIPATIONsensomotorinen kehitysdevelopmental disabilityCHILDRENPhysical Therapy Sports Therapy and RehabilitationpitkittäistutkimusliikuntaBody Mass IndexDEFICITSmotorinen kehitysADOLESCENTSAccelerometryHumansOrthopedics and Sports MedicineLongitudinal Studies315 Sport and fitness sciencesmotoriset taidotkehitysvammaisetExercisemotoriikkaOVERWEIGHTmittausEDUCATIONlapsuus1106 Human Movement and Sports Sciences 1116 Medical PhysiologyMotor Skills Disordersmotor competencekehityshäiriötOBESITYChild Preschoolfyysinen kehitysHEALTHTRAJECTORIESkehitysfyysinen aktiivisuusSport SciencesScandinavian Journal of Medicine & Science in Sports
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One uterus bridging three generations: first live birth after mother-to-daughter uterus transplantation

2016

Objective To determine whether a uterus from the mother of a woman with absolute uterine factor infertility can be transplanted to daughter and carry a pregnancy with delivery of a healthy child. Design Part of an observational study. Setting University teaching hospital. Patient(s) Twenty eight-year-old woman with uterine agenesis, her male partner, and her 50-year-old mother. Intervention(s) In vitro fertilization with embryo cryopreservation before live donor uterus transplantation (UTx). Induction immunosuppression. Embryo transfer 12 months after UTx, pregnancy controls, delivery, and hysterectomy. Main Outcome Measure(s) Results of IVF-ET, parameters of pregnancy/birth, and surgical d…

Adultmedicine.medical_specialty46 XX Disorders of Sex Developmentmedicine.medical_treatmentMothersFertilization in VitroHysterectomyCongenital AbnormalitiesUterine AgenesisHospitals University03 medical and health sciences0302 clinical medicinePregnancyUterus transplantationLiving DonorsmedicineHumansMullerian DuctsCryopreservationImmunosuppression TherapySwedenGynecologyPregnancy030219 obstetrics & reproductive medicineHysterectomyCesarean SectionObstetricsbusiness.industryUterusObstetrics and GynecologyMiddle AgedEmbryo Transfermedicine.diseaseEmbryo transferTransplantationFertilityTreatment OutcomeReproductive Medicine030220 oncology & carcinogenesisAdult ChildrenGestationFemalebusinessLive birthInfertility FemaleLive BirthFertility and Sterility
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Early auditory evoked potentials: developmental aspects and validity in neuropaediatric and audiologic disorders.

1984

Auditory evoked potentials and in this context especially five waves in the first 10 ms (early auditory evoked potentials = EAEP) are a diagnostic aid in topodiagnosis of posterior fossa diseases. This is due to waves I to V which arise along the acoustic nerve and in brain stem structures such as medulla, pons and mid-brain. Besides an indication about the site of a lesion in the posterior fossa, wave V allows an objective threshold determination. The present results were gained in normal children aged 1-3 years and in children with neuropaediatric and audiologic disorders.

Adultmedicine.medical_specialtyAgingAdolescentPosterior fossaNeural ConductionContext (language use)AudiologyDiagnostic aidLesionChild DevelopmentMedicineHumansChildHearing DisordersMedullaNeural Conductionbusiness.industryBrain NeoplasmsInfant NewbornInfantDiffuse Cerebral Sclerosis of SchilderLeukodystrophy MetachromaticPonsChild PreschoolPediatrics Perinatology and Child HealthNormal childrenEvoked Potentials Auditorymedicine.symptomNervous System DiseasesbusinessBrain StemEuropean journal of pediatrics
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Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain)

2014

This study was funded by grants from the EU (European Union): NEWGENERIS FP6-2003- Food-3-A-016320, FP7-ENV-2011 cod 282957, HEALTH.2010.2.4.5-1; and by grants from Spain: Instituto de Salud Carlos III (Red INMA G03/176, CB06/02/0031, and FIS-FEDER PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI04/2018, PI04/1436, PI05/1079, PI05/1052, PI06/1213, PI07/0314, PI08/1151, PI09/02647, PI09/02311, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/02429, PI14/0891, PI14/1687, and Miguel Servet CP11/00178 and CP13/00054), Conselleria de Sanitat Generalitat Valenciana, Generalitat de Catalunya (CIRIT 1999SGR 00241), Diputación Foral de Guipúzcoa (DFG/004), Departamento de Sanidad y Consumo Gobierno…

Adultmedicine.medical_specialtyHealth Toxicology and MutagenesisPhysiologyUltrasonography PrenatalFetal Developmentchemistry.chemical_compoundPregnancyInternal medicinemedicineHydrocarbons ChlorinatedHumansFetusPregnancybusiness.industryUltrasoundPublic Health Environmental and Occupational HealthPolychlorinated biphenylHexachlorobenzeneAnthropometrymedicine.disease3. Good healthEndocrinologychemistryMaternal ExposureSpainCohortChildren's HealthGestationFemalebusiness
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