Search results for "Chip"
showing 10 items of 386 documents
An Investigation of the Thermal Effects in Orthogonal Cutting Associated with Multilayer Coatings
2001
Abstract This paper deals with an experimental and analytical investigation into the tool-chip interface behaviour, influencing the temperature and heat transfer at the multilayered coated-tool rake face during orthogonal cutting of carbon and stainless steels. New methodology for assessing the amount of thermal energy generated when machining with a coated tool insert with natural and restricted contact coupled with a metallic chip, using thermophysical properties of the sliding materials is developed in this study. It was proven, based on the heat flux analysis, that the use of advanced coatings with an intermediate Al 2 O 3 layer can substantially improve the heat flow into the chip at d…
A new gas sensor electronic interface with generalized impedance converter
2008
A new gas sensor conditioning circuit that allows a direct resistance-to-frequency conversion, as well as the procedure for the design, is presented. The generalized impedance converter (GIC) proposed is configured as a variable capacitor connected with the capacitor timing terminal of an astable multivibrator implemented by a PSoC (programmable system on chip) microcontroller device. The GIC effective input impedance, which is controlled by the gas sensor resistance, controls the astable output frequency. Good correlation of the experimental output frequency, which depends on the gas concentration, is achieved. The circuit is a simple gas sensor digital interface with frequency output.
Scaling the Sensitivity of Integrated Plasmo-Photonic Interferometric Sensors
2019
We present a new optical biosensing integration approach with multifunctional capabilities using plasmonic and photonic components on the same chip and a new methodology to design interferometric b...
Plasmonic Biosensors for the Detection of Lung Cancer Biomarkers: A Review
2021
Lung cancer is the most common and deadliest cancer type globally. Its early diagnosis can guarantee a five-year survival rate. Unfortunately, application of the available diagnosis methods such as computed tomography, chest radiograph, magnetic resonance imaging (MRI), ultrasound, low-dose CT scan, bone scans, positron emission tomography (PET), and biopsy is hindered due to one or more problems, such as phenotypic properties of tumours that prevent early detection, invasiveness, expensiveness, and time consumption. Detection of lung cancer biomarkers using a biosensor is reported to solve the problems. Among biosensors, optical biosensors attract greater attention due to being ultra-sensi…
Developing Domain-Knowledge Evolutionary Algorithms for Network-on-Chip Application Mapping
2013
This paper addresses the Network-on-Chip (NoC) application mapping problem. This is an NP-hard problem that deals with the optimal topological placement of Intellectual Property cores onto the NoC tiles. Network-on-Chip application mapping Evolutionary Algorithms are developed, evaluated and optimized for minimizing the NoC communication energy. Two crossover and one mutation operators are proposed. It is analyzed how each optimization algorithm performs with every genetic operator, in terms of solution quality and convergence speed. Our proposed operators are compared with state-of-the-art genetic operators for permutation problems. Finally, the problem is approached in a multi-objective w…
A multi-objective strategy for concurrent mapping and routing in networks on chip
2009
The design flow of network-on-chip (NoCs) include several key issues. Among other parameters, the decision of where cores have to be topologically mapped and also the routing algorithm represent two highly correlated design problems that must be carefully solved for any given application in order to optimize several different performance metrics. The strong correlation between the different parameters often makes that the optimization of a given performance metric has a negative effect on a different performance metric. In this paper we propose a new strategy that simultaneously refines the mapping and the routing function to determine the Pareto optimal configurations which optimize averag…
Comparative analysis of biochip mosaic-based indirect immunofluorescence with enzyme-linked immunosorbent assay for diagnosing myasthenia gravis
2021
Background: The detection of anti-acetylcholine receptor (AChR) and anti-muscle-specific tyrosine kinase (MuSK) antibodies is useful in myasthenia gravis (MG) diagnosis and management. BIOCHIP mosaic-based indirect immunofluorescence is a novel analytical method, which employs the simultaneous detection of anti-AChR and anti-MuSK antibodies in a single miniature incubation field. In this study, we compare, for the first time, the BIOCHIP MG mosaic with conventional enzyme-linked immunosorbent assay (ELISA) in the diagnosis of MG. Methods: A total of 71 patients with MG diagnosis were included in the study. Anti-AChR and anti-MuSK antibodies were measured separately by two different ELISA an…
mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data
2015
Background Over-representation of predicted miRNA targets in sets of genes regulated by a given transcription factor (e.g. as defined by ChIP-sequencing experiments) helps to identify biologically relevant miRNA targets and is useful to get insight into post-transcriptional regulation. Findings To facilitate the application of this approach we have created the mBISON web-application. mBISON calculates the significance of over-representation of miRNA targets in a given non-ranked gene set. The gene set can be specified either by a list of genes or by one or more ChIP-seq datasets followed by a user-defined peak-gene association procedure. mBISON is based on predictions from TargetScan and us…
Utilization of muddy detritus as organic matter source by the fan mussel Pinna nobilis.
2014
The knowledge of the feeding habits in marine species is fundamental to better understand their relationship with the environment. Although phytoplankton has been traditionally reported as the main food source consumed by the Mediterranean fan mussel Pinna nobilis, recent studies have revealed that detritus represents an important food source for this species. We analysed the degree of acceptance of muddy detritus and the utilisation of its organic matter (OM) by P. nobilis on a group of 21 individuals (30.3-59.7 cm of total shell height (Ht)). The specimens were collected between July and September 2012 in two areas (43°04´25” N; 5°46´7” E and 43°04´34” N; 5°47´32” E) of the Embiez archipe…
Ferula sommieriana (Apiaceae), a new species from Pelagie Islands (Sicily)
2021
Ferula sommieriana, a new species occurring in Lampedusa and Linosa, islands of Pelagie Archipelago in the Sicilian Channel, is described and illustrated. Previously it was attributed to F. communis, from which it differs in several features regarding mainly the morphology and anatomy of terminal leaf lobes and mericarps, as well as the shape and size of reproductive structures. Its ecology, conservation status and relationships with other allied Mediterranean species of the sect. Ferula are provided, as well as the analytical keys of the species belonging to the aforesaid section.