Search results for "Cholin"
showing 10 items of 1261 documents
Neurocognitive processing of auditorily and visually presented inflected words and pseudowords: Evidence from a morphologically rich language
2009
The aim of the study was to investigate how the input modality affects the processing of a morphologically complex word. The processing of Finnish inflected vs. monomorphemic words and pseudowords was examined during a lexical decision task, using behavioral responses and event-related potentials. The stimuli were presented in two modalities, visually and auditorily, to two groups of participants. Half of the words and pseudowords carried a case-inflection. At the behavioral level, the inflected words elicited a processing cost with longer decision latencies and higher error rates. At the neural level, pseudowords elicited an N400 effect, which was more pronounced in the visual modality. In…
Effects of allergen exposure on methacholine and AMP-induced air trapping in pollen-sensitive subjects
2011
Summary Background The effect of pro-inflammatory stimuli on bronchoconstrictor-induced air trapping has not been studied. Objective To determine the effect of natural allergen exposure, a pro-inflammatory stimulus, on methacholine- and adenosine 5′-monophospate (AMP)-induced air trapping. Methods Airway responsiveness to methacholine and AMP before and during the pollen season was obtained in 25 subjects with pollen allergy and in 10 healthy controls. The response was expressed by the sensitivity (PC 20 value) and by the slope and intercept of the FVC values recorded at each step of the challenge against the corresponding FEV 1 values. Results The slope and intercept FVC versus FEV 1 value…
The time course of orthography and phonology: ERP correlates of masked priming effects in Spanish
2009
Abstract One key issue for computational models of visual-word recognition is the time course of orthographic and phonological information during reading. Previous research, using both behavioral and event related brain potential (ERP) measures, has shown that orthographic codes are activated very early but that phonological activation starts to occur immediately afterward. Here we report an ERP masked priming experiment in Spanish that investigates this issue further by using very strict control conditions. The critical phonological comparison was between two pairs of primes having the same orthographic similarity to the target words but differing in phonological similarity (e.g., conal-CA…
A new set of 299 pictures for psycholinguistic studies : French norms for name agreement, image agreement, conceptual familiarity, visual complexity,…
2003
Pictures are often used as stimuli in studies of perception, language, and memory. Since performances on different sets of pictures are generally contrasted, stimulus selection requires the use of standardized material to match pictures across different variables. Unfortunately, the number of standardized pictures available for empirical research is rather limited. The aim of the present study is to provide French normative data for a new set of 299 black-and-white drawings. Alario and Ferrand (1999) were closely followed in that the pictures were standardized on six variables: name agreement, image agreement, conceptual familiarity, visual complexity, image variability, and age of acquisit…
Association of nicotinic acetylcholine receptor subunit alpha 4 polymorphisms with nicotine dependence in 5500 Germans.
2009
Polymorphisms in the CHRNA4 gene coding the nicotinic acetylcholine receptor subunit alpha 4 have recently been suggested to play a role in the determination of smoking-related phenotypes. To examine this hypothesis, we conducted a genetic association study in three large samples from the German general population (N(1)=1412; N(2)=1855; N(3)=2294). Five single-nucleotide polymorphisms in CHRNA4 were genotyped in 5561 participants, including 2707 heavily smoking cases (regularly smoking at least 20 cigarettes per day) and 2399 never-smoking controls (or=100 cigarettes over lifetime). We examined associations of the polymorphisms with smoking case-control status and with the extent of nicotin…
Psycholinguistic norms for 320 fixed expressions (idioms and proverbs) in French
2018
International audience; We provide psycholinguistic norms for a new set of 160 French idiomatic expressions and 160 proverbs: knowledge, predictability, literality, compositionality, subjective and objective frequency, familiarity, age of acquisition (AoA), and length. Different analyses (reliability, descriptive statistics, correlations) performed on the norms are reported and discussed. The norms can be downloaded as supplemental material.
Yes, you can? A speaker’s potency to act upon his words orchestrates early neural responses to message-level meaning
2013
Evidence is accruing that, in comprehending language, the human brain rapidly integrates a wealth of information sources-including the reader or hearer's knowledge about the world and even his/her current mood. However, little is known to date about how language processing in the brain is affected by the hearer's knowledge about the speaker. Here, we investigated the impact of social attributions to the speaker by measuring event-related brain potentials while participants watched videos of three speakers uttering true or false statements pertaining to politics or general knowledge: a top political decision maker (the German Federal Minister of Finance at the time of the experiment), a well…
On the limits of familiarity accounts in lexical decision: The case of repetition effects
2019
Recent modelling accounts of the lexical decision task have suggested that the reading system performs evidence accumulation to carry out some functions. Evidence accumulation models have been very successful in accounting for effects in the lexical decision task, including the dissociation of repetition effects for words and nonwords (facilitative for words but inhibitory for nonwords). The familiarity of a repeated item triggers its recognition, which facilitates ‘word’ responses but hampers nonword rejection. However, reports of facilitative repetition effects for nonwords with several repetitions in short blocks challenge this hypothesis and favour models based on episodic retrieval. T…
Inhibition of nitric oxide activity by arginine analogs in human renal arteries
2001
Abstract Background: Plasma levels of endogenous guanidine compounds are increased in various pathologic conditions, including chronic renal failure. In the present study we tested the effects of some of these compounds on basal and stimulated nitric oxide activity in human renal arteries. Methods: Rings from human renal arteries were obtained from 22 patients undergoing nephrectomy. The rings were suspended in organ baths for isometric recording of tension. We then studied the effects of N G -monomethyl- l -arginine (L-NMMA), N G , N G -dimethyl- l -arginine (asymmetrical dimethylarginine [ADMA]), aminoguanidine (AG), and methylguanidine (MG) on artery rings under basal and stimulated cond…
Wording effects and the factor structure of the 12-item General Health Questionnaire (GHQ-12)
2021
The 12-item version of the General Health Questionnaire (GHQ-12) has become a popular screening instrument with which to measure general psychological health in different settings. Previous studies into the factorial structure of the GHQ-12 have mainly supported multifactor solutions, and only a few recent works have shown that the GHQ-12 was best represented by a single substantive factor when method effects associated with negatively worded items were considered. Confirmatory factor analysis was applied to compare competing measurement models from previous research, including correlated traits-correlated methods and correlated traits-correlated uniquenesses approaches, to obtain further e…