Search results for "Chromosome Mapping"

showing 3 items of 193 documents

The banding pattern of polytene chromosomes of Drosophila guanche compared with that of D. subobscura.

1987

A detailed map of the salivary gland chromosomes of Drosophila guanche is presented and compared to the standard gene arrangements of D. subobscura. Generally, the polytene chromosomc banding patterns of the two species show a high degrce of homology. Only Segment I of the sex chromosome (Chromosome A) shows marked differences. The banding pattern proposed for this segment in D. guanche could have originated from a cluster of overlapping inversions including A1 arrangement.

medicine.medical_specialtyDrosophila guanchePlant ScienceHomology (biology)Species SpecificityDrosophilidaeGeneticsmedicinePhotographyAnimalsGeneticsPolytene chromosomeSex ChromosomesbiologyCytogeneticsChromosomeChromosome MappingKaryotypeGeneral Medicinebiology.organism_classificationChromosome BandingInsect ScienceChromosome InversionGene ArrangementsAnimal Science and ZoologyDrosophilaGenetica
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A possible susceptibility locus for bipolar affective disorder in chromosomal region 10q25--q26.

2000

In an attempt to identify susceptibility loci for bipolar affective disorder, we are currently conducting a systematic genome screen with highly polymorphic microsatellite markers at an average marker spacing of 10 cM in a series of 75 families, comprising 66 families from Germany, eight families from Israel, and one family from Italy. The families were ascertained through index cases with bipolar affective disorder. The distribution of diagnoses is as follows: 126 individuals with bipolar I disorder, 40 with bipolar II disorder, 14 with schizoaffective disorder of the bipolar type, 40 individuals with recurrent unipolar depression, 51 with a minor psychiatric diagnosis, and two individuals…

musculoskeletal diseasescongenital hereditary and neonatal diseases and abnormalitiesBipolar DisorderLocus (genetics)Nuclear FamilyCellular and Molecular NeurosciencemedicineHumansGenetic Predisposition to DiseaseBipolar disorderMolecular BiologyGeneticsFamily HealthChromosomes Human Pair 10Chromosome MappingGene Localizationmedicine.diseaseSib pairseye diseasesbody regionsPsychiatry and Mental healthChromosomal regionSusceptibility locussense organsPsychologyManic depressionMicrosatellite RepeatsMolecular psychiatry
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Early evolutionary colocalization of the nuclear ribosomal 5S and 45S gene families in seed plants: evidence from the living fossil gymnosperm Ginkgo…

2012

In seed plants, the colocalization of the 5S loci within the intergenic spacer (IGS) of the nuclear 45S tandem units is restricted to the phylogenetically derived Asteraceae family. However, fluorescent in situ hybridization (FISH) colocalization of both multigene families has also been observed in other unrelated seed plant lineages. Previous work has identified colocalization of 45S and 5S loci in Ginkgo biloba using FISH, but these observations have not been confirmed recently by sequencing a 1.8 kb IGS. In this work, we report the presence of the 45S–5S linkage in G. biloba, suggesting that in seed plants the molecular events leading to the restructuring of the ribosomal loci are much o…

phylogenetic relictDNA PlantPseudogeneMolecular Sequence Dataintergenic spacerrDNAEvolution MolecularGymnospermTranscription (biology)GeneticsGene family45S–5S unitGeneGenetics (clinical)In Situ Hybridization FluorescenceGeneticsCell NucleusbiologyFossilsGinkgoRNA Ribosomal 5SColocalizationChromosome MappingGinkgo bilobaGenes rRNARibosomal RNAbiology.organism_classificationribosomal pseudogenes gymnospermSeedsOriginal Article
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