Search results for "Chronic"
showing 10 items of 3309 documents
"Le jeu est tellement un vice humain..." : le jeu et les joueurs dans les chroniques zoliennes
2016
Émile Zola’s journalistic production, such as chronicles, reportages, polemic texts, etc., was created during a few decades parallelly to his fictional writings. Its subject is often social leisure, including gambling, officially banned in France of the Second Empire but practiced secretly by the social elites and the middle class. Zola describes some places where clandestine gambling games are organized, as well as the gamblers’ behavior. Considering the entire Second Empire regime as a huge gambling house, the author underlines the role of horse racing and stock exchange operations as legał ways of wagering. Zolas particular sense of humor contributes to his chronicles’ documentary and an…
V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenou…
2010
Abstract Imatinib mesylate (imatinib), a competitive inhibitor of the BCR-ABL tyrosine kinase, is highly effective against chronic myelogenous leukemia (CML) cells. However, because 20–30% of patients affected by CML display either primary or secondary resistance to imatinib, intentional activation of Vγ9Vδ2 T cells by phosphoantigens or by agents that cause their accumulation within cells, such as zoledronate, may represent a promising strategy for the design of a novel and highly innovative immunotherapy capable to overcome imatinib resistance. In this study, we show that Vγ9Vδ2 T lymphocytes recognize, trogocytose, and efficiently kill imatinib-sensitive and -resistant CML cell lines pre…
Owrzodzenie podudzia związane z niewydolnością żyły mięśnia brzuchatego łydki - opis przypadku
2008
Przedstawiono przypadek chorego z żylnymi owrzodzeniami goleni na tle niewydolności żyły mięśnia brzuchatego łydki z układem refleksowym typu „enigma of the gastrocnemius vein”. Operacja polegała na wybiórczym podwiązaniu niewydolnego perforatora łączącego żyłę mięśnia brzuchatego łydki z żyłą odstrzałkową. Po operacji owrzodzenia wygoiły się oraz ustąpił refluks w układzie żyły mięśnia brzuchatego łydki. Omówiono również taktykę operacji u chorych z żylakami towarzyszącymi niewydolności żyły mięśnia brzuchatego łydki.
Tracking the change in an Institutional Genre: A Diachronic Corpus-based study of White House Press Briefings
2013
The aim of the paper is to study the evolution of the language of the specific genre of white house press briefings across 18 years. Phraseologies will be taken into consideration in order to compare and contrast the language of the 'podium' during three different administrations: Clinton, Bush and Obama.
Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia.
2010
Abstract The clinical relevance of angiopoietin-2 (Ang2) in chronic lymphocytic leukemia (CLL) was previously suggested by the association between high Ang2, and shorter progression-free survival reported in small series of patients. Here, we evaluated Ang2 glycoprotein levels in plasma samples collected from a multicentric cohort of CLL patients (n = 316) using an enzyme-linked immunosorbent assay method, and we investigated its prognostic role in relation to time to first treatment (TTFT) and overall survival. Based on a cutoff equal to 2459 pg/mL, we divided our cohort in 2 subsets (high and low Ang2) composing 100 (31.6%) and 216 (68.4%) patients, respectively. High Ang2 was predictive …
Vitom® 3D in arterio-venous fistulas: Single centre preliminary surgical experience
2021
Background: Arteriovenous fistula (AVF) is the vascular access of choice for hemodialysis patients. A correct microsurgical vascular anastomoses is essential to the optimal care of patients. Loupes can help surgeons perform such procedures, but often cause neck or back pain and fatigue. Aim: This study aimed to evaluate whether a video telescopic operating microscope (VITOM®; Karl Storz Endoscopy GmbH, Tuttlingen, Germany) could be used as a substitute for loupes to create microsurgical vascular anastomoses. Methods: We evaluated microsurgical anastomoses with VITOM® in 10 patients (6 male, 4 female) from January 2019 to December 2019. The created anastomoses were 7 side-to-side, 2 side-to-…
Diagnosis and treatment of chronic synovitis in patients with haemophilia: consensus statements from the Italian Association of Haemophilia Centres
2022
Although synovitis is recognized as a marker of joint disease activity, its periodic assessment is not included in routine clinical surveillance of patients with haemophilia (PwH). In order to evaluate the current knowledge and to identify controversial issues, a preliminary literature search by the Musculoskeletal Committee of the Italian Association of Haemophilia Centres (AICE) has been conducted. Statements have been established and sent to the Italian AICE members to collect their level of agreement or disagreement by a Delphi process. Thirty-seven consensus recommendations have been drafted. We found a general agreement on the indication to consider the presence of synovitis as a mark…
Coexistence of frailty syndrome and the level of health behaviors in elderly patients with chronic obstructive pulmonary disease
2023
Wprowadzenie: Przyspieszenie tempa starzenia się populacji, związane z tym ryzyko występowania zespołu słabości oraz wzrost liczby osób żyjących z przewlekłą obturacyjną chorobą płuc (POChP) powodują, że przyszłe kierunki polityki zdrowotnej powinny się skupiać na działaniach z zakresu promocji zdrowia, potęgowaniu zachowań prozdrowotnych, utrzymaniu lub poprawie sprawności funkcjonalnej starzejących się ludzi. Cel pracy: Analiza współwystępowania zespołu kruchości oraz nasilenia zachowań zdrowotnych u pacjentów w wieku podeszłym z POChP, jak również ustalenie czynników determinujących nasilenie zachowań zdrowotnych. Materiał i metody: Zbadano 100 pacjentów z rozpoznaniem POChP (średnia wie…
Incidence of hepatitis C virus infection in patients with chronic kidney disease on conservative therapy
2011
Grazoprevir/elbasvir for the immediate treatment of recently acquired HCV genotype 1 or 4 infection in MSM.
2020
Abstract Background In Europe, increases in HCV infection have been observed over the last two decades in MSM, making them a key population for recently acquired HCV. Alternative combinations of direct-acting antiviral agents against early HCV infection need to be assessed. Patients and methods In this pilot trial, MSM with recently acquired genotype 1 or 4 HCV infection were prospectively included and received 8 weeks of oral grazoprevir 100 mg and elbasvir 50 mg in a fixed-dose combination administered once daily. The primary endpoint was sustained virological response evaluated 12 weeks after the end of treatment (EOT) (SVR12). Secondary endpoints were the virological characterization of…