Search results for "Circulation"

Vascular Microarchitecture of Murine Colitis-Associated Lymphoid Angiogenesis

2009

In permissive tissues, such as the gut and synovium, chronic inflammation can result in the ectopic development of anatomic structures that resemble lymph nodes. These inflammation-induced structures, termed lymphoid neogenesis or tertiary lymphoid organs, may reflect differential stromal responsiveness to the process of lymphoid neogenesis. To investigate the structural reorganization of the microcirculation involved in colonic lymphoid neogenesis, we studied a murine model of dextran sodium sulfate (DSS)-induced colitis. Standard 2-dimensional histology demonstrated both submucosal and intramucosal lymphoid structures in DSS-induced colitis. A spatial frequency analysis of serial histolog…

Effects of a low-frequency sound wave therapy programme on functional capacity, blood circulation and bone metabolism in frail old men and women

2009

Objective: To evaluate the effects of a low-frequency sound wave therapy programme on functional capacity, blood circulation and bone metabolism of the frail elderly. Design: Single-blind, randomized, controlled trial. Setting: Two senior service centres. Subjects: Forty-nine volunteers (14 males and 35 females) aged 62—93 years with up to 12 diagnosed diseases were allocated in either the intervention group (n = 30) or control group (n = 19). Intervention: The intervention group underwent sound wave therapy, 3—5 times a week for 30 minutes per session over a period of 6 months. The control group received no intervention. Main measurements: Blood pressure, functional capacity, mobility, bo…

West African Monsoon influence on the summer Euro-Atlantic circulation

2011

International audience; The West African Monsoon (WAM) influence on the interannual variability of the summer atmospheric circulation over North Atlantic and Europe is investigated over the period 1971-2000. A set of sensitivity experiments performed through the Arpege-Climat atmospheric general circulation model is analyzed, using the so-called "grid-point nudging" technique, where the simulated atmospheric fields in the WAM region are relaxed towards the ERA40 reanalysis. Observations confirm that a sizable part of the Euro-Atlantic circulation variability is related to the WAM, with anomalies of reinforced convection in the Sudan-Sahel region associated with positive North Atlantic Oscil…

Tropical–extratropical interactions related to upper-level troughs at low latitudes

2007

Abstract Momentum and kinetic energy fluxes associated with low-latitude transient disturbances at upper-levels play an important role in the general circulation of the atmosphere. They are related to eastward and equatorward propagating, positively tilted wave trains from the extratropics. Theoretical, modelling and observational studies show that this particular kind of tropical–extratropical interaction is most common in regions of mean upper-level westerlies at low latitudes, i.e. over the central and eastern Pacific and Atlantic Oceans during boreal winter and spring. The penetration of an upper-level trough into the Tropics is often associated with enhanced convection and the formatio…

Influence of the Madden-Julian Oscillation on East African rainfall. Part I: Intraseasonal variability and regional dependency

2006

The influence of the Madden–Julian Oscillation (MJO) on rainfall amounts over Equatorial East Africa (Kenya and northern Tanzania) is analysed for the period 1979–95 at the intraseasonal (pentad) time-scale. The two rainy seasons (March to May and October to December) are considered. Intraseasonal wet events in East Africa are embedded in large-scale zonal circulation anomaly patterns along the equator, showing distinct eastward propagation. It is further found that these ‘wet’ events display a clear phasing with respect to the MJO cycle. This phasing is expressed as out-of-phase variations between the Highland and the coastal areas. Such a pattern is suggested to reflect different rain-cau…

Prevalence of anatomical variants and coronary anomalies in 543 consecutive patients studied with 64-slice CT coronary angiography

2008

The aim of our study was to assess the prevalence of variants and anomalies of the coronary artery tree in patients who underwent 64-slice computed tomography coronary angiography (CT-CA) for suspected or known coronary artery disease. A total of 543 patients (389 male, mean age 60.5 +/- 10.9) were reviewed for coronary artery variants and anomalies including post-processing tools. The majority of segments were identified according to the American Heart Association scheme. The coronary dominance pattern results were: right, 86.6%; left, 9.2%; balanced, 4.2%. The left main coronary artery had a mean length of 112 +/- 55 mm. The intermediate branch was present in the 21.9%. A variable number …

Stable microvascular angina: instrumental evaluation of coronary microvascular dysfunction with coronary angiography and myocardial scintigraphy

2014

Insights Into the Mechanisms of Phreatic Eruptions From Continuous High Frequency Volcanic Gas Monitoring: Rincón de la Vieja Volcano, Costa Rica

2019

OVSICORI Understanding the trigger mechanisms of phreatic eruptions is key to mitigating the effects of these hazardous but poorly forecastable volcanic events. It has recently been established that high-rate volcanic gas observations are potentially very suitable to identifying the source processes driving phreatic eruptions, and to eventually detecting precursory changes prior to individual phreatic blasts. In February-May 2017, we deployed a Multi-GAS instrument to continuously monitor gas concentrations in the crater lake plume of Rincón de la Vieja, a remote and poorly monitored active volcano in Costa Rica, site of frequent phreatic/phreatomagmatic eruptions. Forty-two phreatic/phreat…

Editorial – About a ‚PLATO‘

2017

While learning has constantly been an object of research in manifold disciplines and fields, it has generally been understood in a positive sense. In the Age of Information, we are witnessing an increasing number of phenomena in the context of knowledge construction and accumulation that we describe as “negative learning”. This includes, for example, the deliberate circulation of counterfactual knowledge leading to negative learning outcomes, i.e., deficient decision-making and acting, like medical errors.

Anti-Hypotensive Treatment and Endothelin Blockade Synergistically Antagonize Exercise Fatigue in Rats under Simulated High Altitude

2013

Rapid ascent to high altitude causes illness and fatigue, and there is a demand for effective acute treatments to alleviate such effects. We hypothesized that increased oxygen delivery to the tissue using a combination of a hypertensive agent and an endothelin receptor A antagonist drugs would limit exercise-induced fatigue at simulated high altitude. Our data showed that the combination of 0.1 mg/kg ambrisentan with either 20 mg/kg ephedrine or 10 mg/kg methylphenidate significantly improved exercise duration in rats at simulated altitude of 4,267 m, whereas the individual compounds did not. In normoxic, anesthetized rats, ephedrine alone and in combination with ambrisentan increased heart…