Search results for "Clara"

showing 10 items of 484 documents

Assessing the added value of the recent declaration on unregulated fishing for sustainable governance of the central Arctic Ocean

2016

Accepted manuscript version. Published version available at https://doi.org/10.1016/j.marpol.2016.01.013. Accepted manuscript version, licensed CC BY-NC-ND 4.0. The ‘Declaration concerning the prevention of unregulated high seas fishing in the central Arctic Ocean’ signed by the Arctic 5 nations, limits unregulated high seas fishing in the central part of the Arctic Ocean, and holds potential social, economic and political impacts for numerous stakeholders. In this paper, the four Interim Measures in the Declaration are discussed and what value these measures bring beyond the existing international agreements is explored. It is found that even though the Declaration fills a gap in the manag…

0106 biological sciencesEconomics and EconometricsArctic five010504 meteorology & atmospheric sciencesFishingDeclarationDeclarationManagement Monitoring Policy and LawAquatic ScienceFish stock01 natural sciences[SHS]Humanities and Social SciencesUnited Nations Convention on the Law of the SeaInterimArctic Ocean14. Life underwaterVDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920Digital media0105 earth and related environmental sciencesGeneral Environmental ScienceVDP::Agriculture and fishery disciplines: 900::Fisheries science: 920business.industry010604 marine biology & hydrobiologyResource managementEnvironmental resource managementExclusive economic zoneArctic Ocean; Fishing; Resource management; Arctic five; DeclarationArcticInternational waters13. Climate actionFishing/dk/atira/pure/core/keywords/digitale_medienbusinessLaw
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The role of (E)-6-chloro-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-2-styrylquinazolin-4(3H)-one in the modulation of cannabinoidergic system. A pilot stu…

2018

Abstract Background Compounds acting on endocannabinoid system regulate different neuronal processes through the cannabinoid receptors activation. The main aim of this study was determining whether the 2-styrylquinazolin-4(3H)-one 5, a structural analogue of rimonabant, was able to counteract the behavioural signs of the activation of the endocannabinoidergic system induced by CP 55.940. Methods Behavioural assessment was carried out using the tetrad task and the novel object recognition test. The endocannabinoidergic system activation was possible by the administration of CP 55.940 and 30 min after rats were tested in the tetrad task for the evaluation of the antinociceptive-, cataleptic-,…

0301 basic medicineAgonistCannabinoid receptormedicine.drug_classmedicine.medical_treatmentPilot ProjectsPharmacologyCannabinoidergicStyrenes03 medical and health sciences0302 clinical medicineRimonabantmedicineAnimalsRats WistarLatency (engineering)PharmacologyDose-Response Relationship DrugCannabinoid CB1 receptor antagonist Quinazolinone derivate Tetrad task Declarative memoryCannabinoidsChemistryRecognition PsychologyGeneral MedicineCyclohexanolsEndocannabinoid systemSettore CHIM/08 - Chimica FarmaceuticaRats030104 developmental biologyNociceptionQuinazolinesSettore BIO/14 - FarmacologiaCannabinoidLocomotion030217 neurology & neurosurgerymedicine.drug
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Communication about vaccination: A shared responsibility

2016

ABSTRACT Vaccine hesitancy is an important issue to be addressed, due to the risk of decrease of vaccination coverage and consequent control of preventable diseases. While it is not considered a specific determinant, poor or inadequate communication can contribute to vaccine hesitancy and negatively influence vaccination uptake. As a contribution to the ongoing discussion regarding this theme and in the perspective of the implementation of the upcoming national vaccination plan in Italy, the Erice Declaration was drafted by experts in the field of immunization following a 5-day residential, independent workshop regarding communication topics in vaccinology. The aim of the current letter is …

0301 basic medicineLetter030106 microbiologyImmunologyControl (management)educationDeclarationCommunicable DiseasesEducation03 medical and health sciences0302 clinical medicineDisease TransmissionDisease Transmission InfectiousImmunology and AllergyMedicineHumans030212 general & internal medicineHealth EducationPharmacologyvaccination coveragebusiness.industrycommunicationHealth PolicyVaccinationInfectiousnational vaccination planPublic relationsPatient Acceptance of Health CareVaccinationIdentification (information)Immunizationcommunication; Italy; national vaccination plan; vaccination coverage; vaccine hesitancy; Communicable Diseases; Disease Transmission Infectious; Education; Health Policy; Humans; Italy; Vaccination; Health Communication; Health Education; Patient Acceptance of Health CareItalyHealth CommunicationVaccination coverageImmunologyItaly; communication; national vaccination plan; vaccination coverage; vaccine hesitancyvaccine hesitancybusinessShared responsibility
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Protein misfolding, amyotrophic lateral sclerosis and guanabenz: Protocol for a phase II RCT with futility design (ProMISe trial)

2017

IntroductionRecent studies suggest that endoplasmic reticulum stress may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS) through an altered regulation of the proteostasis, the cellular pathway-balancing protein synthesis and degradation. A key mechanism is thought to be the dephosphorylation of eIF2α, a factor involved in the initiation of protein translation. Guanabenz is an alpha-2-adrenergic receptor agonist safely used in past to treat mild hypertension and is now an orphan drug. A pharmacological action recently discovered is its ability to modulate the synthesis of proteins by the activation of translational factors preventing misfolded protein accumula…

0301 basic medicineOncologyPathologyamyotrophic lateral sclerosisamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response; adrenergic alpha-2 receptor agonist s; age of onset; amyotrophic lateral sclerosis; disease progression; double-blind method; endoplasmic reticulum stress; guanabenz; humans; italy; medical futility; neuroprotective agents; proteostasis deficienciesamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response; Medicine (all)randomized clinical trial guanabenzHelsinki declaration0302 clinical medicineProtocolAdrenergic alpha-2 Receptor Agonists1506Amyotrophic lateral sclerosisAge of OnsetGuanabenzMedicine (all)amyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein responseNeurodegenerationamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response;amyotrophic lateral sclerosis; guanabenz; motor neurone disease; neuromuscular disease; randomized clinical trial; unfolded protein response; Adrenergic alpha-2 Receptor Agonists; Age of Onset; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Endoplasmic Reticulum Stress; Guanabenz; Humans; Italy; Medical Futility; Neuroprotective Agents; Proteostasis DeficienciesGeneral Medicineunfolded protein responseEndoplasmic Reticulum StressRiluzoleNeuroprotective AgentsNeurologyTolerabilityItalyDisease Progression1713GuanabenzMedical Futilitymedicine.drugmedicine.medical_specialtyamyotrophic lateral sclerosis; motor neurone disease; neuromuscular disease; randomized clinical trial guanabenz; unfolded protein response; Adrenergic alpha-2 Receptor Agonists; Age of Onset; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Endoplasmic Reticulum Stress; Guanabenz; Humans; Italy; Medical Futility; Neuroprotective Agents; Proteostasis Deficiencies; Medicine (all)Neuroprotection03 medical and health sciencesmotor neurone diseaseDouble-Blind MethodInternal medicinemedicineHumansProteostasis Deficienciesbusiness.industryAmbientaleneuromuscular diseaserandomized clinical trialmedicine.diseaseClinical trial030104 developmental biologybusiness030217 neurology & neurosurgery
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Sociología, Derecho y desigualdades sociales. Una propuesta de docencia universitaria crítica

2019

Fil: Di Nella, Dino. Universidad Nacional de Río Negro. Río Negro, Argentina. Fil: Almeda, Elisabet. Universidad de Barcelona. Catalunya, España. Fil: Camps Calvet, Clara. Universidad de Barcelona. Catalunya, España. Fil: Giordana, Patricia. Universidad Nacional de Río Negro. Río Negro, Argentina. Fil: Loggiacco, Camila. Universidad Nacional de Río Negro. Río Negro, Argentina. Fil: D'Alfonso, Luis. Universidad Nacional de Río Negro. Río Negro, Argentina. Critic education in human rights and social inequalities must be able to capture holistic and mutidmiensional sphere that Human Rights requires. This study introduces the basis in which critic university teaching proposal is carectarized by…

1137-7038 8537 Arxius de sociologia 525290 2019 40 7038141 SociologíaUniversitiesAlmeda SamaranchCiencias SocialesUniversitatsDrets socials i econòmicsteam workUniversidadesD'Alfonsohuman rightsspecially relevant ones in this field: professional interdisciplinaryenseñanza de la sociología y el derechoGestió de la innovacióSociologyDerecho y desigualdades sociales. Una propuesta de docencia universitaria crítica Di NellaCamps CalvetCamillaUNESCO::SOCIOLOGÍATeaching innovationprofessional interdisciplinary [specially relevant ones in this field]DinoGestión de la innovaciónproblem solving and the utilization of ICTs. Innovación docentedesigualdades socialesteaching of sociology and lawLoggiacco:SOCIOLOGÍA [UNESCO]Derechos sociales y económicosGiordanaDerecho (general)ClaraSociologiasocial inequalities. 65 70ElisabetLuis Critic education in human rights and social inequalities must be able to capture holistic and mutidmiensional sphere that Human Rights requires. This study introduces the basis in which critic university teaching proposal is carectarized by different active learning mechanismes with the students for the achivement of four transversal competencesSocial and economic rightsPensamiento críticoderechos humanosSociologíaPensament críticCritical thinkingInnovation managementPatricia
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Presentación e ingreso de determinadas declaraciones y autoliquidaciones tributarias durante el Estado de Alarma

2020

[ES] Desde la declaración del estado de alarma como consecuencia de la crisis sanitaria provocada por el COVID-19, han sido aprobados numerosos reales decretos. Entre ellos, uno de los principales desde la perspectiva tributaria es el Real Decreto-ley 14/2020, en virtud del cual se ampliaba el plazo de presentación e ingreso de numerosos tributos, destacando, entre otros, el IVA y el IS. Además, las comunidades autónomas también han aprobado medidas relativas a la ampliación del plazo de presentación e ingreso de los tributos respecto de los que tienen atribuidas competencias.

:CIENCIAS JURÍDICAS [UNESCO]Deferment of paymentAutonomous regionAutoliquidaciones tributariasDeclaraciones tributariasEstado de alarmaTax returns extensionComunidades autónomasPayment in instalmentsUNESCO::CIENCIAS JURÍDICASState of alarmFraccionamientoECONOMIA FINANCIERA Y CONTABILIDADAplazamientoAmpliación plazo
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70 años de la Declaración Universal de Derechos Humanos : introducción a una colección plural de reflexiones | 70 years of the Universal Declaration …

2019

Resumen: Tras una breve reflexión introductoria, este texto presenta algunos de los trabajos derivados del Congreso Internacional sobre el 70 Aniversario de la Declaración Universal de Derechos Humanos, que tuvo lugar en Valencia en diciembre de 2018. Los trabajos se han clasificado en siete secciones: 1) Ponencias invitadas; 2) Violencia de género y derechos de las mujeres; 3) Empresas multinacionales y derechos humanos; 4) Memoria histórica y derechos humanos; 5) Nuevos escenarios y nuevas garantías para los derechos; 6) Contextos y vulnerabilidades; 7) Perspectivas.
 Abstract: After a brief introductory reflection, this text presents some of the works derived from the International …

:CIENCIAS JURÍDICAS [UNESCO]DerechoHuman rightsmedia_common.quotation_subjectK201-487DeclarationPhilosophyUNESCO::CIENCIAS JURÍDICASPolitical scienceJurisprudence. Philosophy and theory of lawLawHumanitiesmedia_commonPlural
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Los derechos de las personas LGBTI : ¿hacia un derecho a la orientación sexual y la identidad de género?

2020

Este trabajo tiene por objeto un estudio de los derechos de las minorías sexuales en el marco del sistema internacional de derechos humanos. Ni la Declaración Universal de Derechos Humanos, ni los tratados posteriores contemplan un derecho específico que reconozca y asegure una vida digna para el colectivo de personas LGBTI. Este artículo reivindica “un derecho a la orientación sexual y la identidad de género” que proteja la especial situación de estas personas en el mundo. Para ello, se estudia y analiza la labor del Alto Comisionado de Naciones Unidas para los Derechos Humanos y el Consejo de Derechos Humanos de Naciones Unidas y se hace referencia a la doctrina jurisprudencial del Tribun…

:CIENCIAS JURÍDICAS [UNESCO]Gender identityHuman rightsmedia_common.quotation_subjectK201-487DeclarationDoctrinePhilosophyWork (electrical)Special situationOrder (business)UNESCO::CIENCIAS JURÍDICASLawPolitical scienceSexual orientationJurisprudence. Philosophy and theory of lawLawmedia_common
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La democracia y los derechos universales frente al auge del populismo | Democracy and universal rights against the rise of populism

2019

La democracia y los derechos universales frente al auge del populismo
 Discurso inaugural en el Congreso Internacional por el 70º Aniversario de la Declaración Universal de Derechos Humanos Instituto de Derechos Humanos de la Universidad de Valencia. Del 10 al 12 de diciembre de 2018, Valencia, España
 Democracy and universal rights against the rise of populism
 Opening speech at the International Congress for the 70th Anniversary of the Universal Declaration of Human Rights. Human Rights Institute of the University of Valencia. From December 10 to 12, 2018, Valencia, Spain

:CIENCIAS JURÍDICAS [UNESCO]Human rightsbiologymedia_common.quotation_subjectK201-487Declarationbiology.organism_classificationDemocracyPopulismPhilosophyUNESCO::CIENCIAS JURÍDICASPolitical scienceInternational congressJurisprudence. Philosophy and theory of lawLawHumanitiesValenciamedia_commonCuadernos Electrónicos de Filosofía del Derecho
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Declaration of will of persons with disabilities in the general theory of legal act and the new perspective based on supports. A study of peruvian law

2021

Indexado en Redib La Convención sobre los Derechos de las Personas con Discapacidad ha supuesto, en términos generales, un replanteamiento de la idea de autonomía de la voluntad al reconocer plena capacidad jurídica en todo sujeto con independencia de su discapacidad. Esta nueva realidad viene a modificar el modo de conceptuar e interpretar la declaración de voluntad en la teoría general del acto jurídico, y muy en especial, cuando la capacidad natural de conocer y querer puede venir naturalmente limitada por una discapacidad psíquica o por un estado de coma. La formación interna de la voluntad y su manifestación se vuelve un asunto complejo, sobre todo cuando los apoyos podrían no ser gara…

:CIENCIAS JURÍDICAS [UNESCO]People with disabilitiesDerecho / Derecho civilPersonas con discapacidadUNESCO::CIENCIAS JURÍDICAS//purl.org/pe-repo/ocde/ford#5.05.00 [https]Declaration of intentionDeclaración de voluntad (Derecho)
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