Search results for "Clase"
showing 10 items of 319 documents
Presynaptic nitric oxide/cGMP facilitates glutamate release via hyperpolarization-activated cyclic nucleotide-gated channels in the hippocampus
2011
In hippocampal neurons, synaptic transmission is affected by a variety of modulators, including nitric oxide (NO), which was proposed as a retrograde messenger as long as two decades ago. NO signals via two NO-sensitive guanylyl cyclases (NO-GCs) (NO-GC1 and NO-GC2) and the subsequent increase in cGMP. Lack of long-term potentiation in mice deficient in either one of the two NO-GCs demonstrates the involvement of both NO-GCs in synaptic transmission. However, the physiological consequences of NO/cGMP and the cellular mechanisms involved are unknown. Here, we analyzed glutamatergic synaptic transmission, most likely reflecting glutamate release, in the hippocampal CA1 region of NO-GC knockou…
Anatectic amphibole and restitic garnet in Variscan migmatite from NE Sardinia, Italy: insights into partial melting from mineral trace elements
2014
We report results of a laser-ICP-MS investigation of trace element contents in the main constituent minerals of an amphibole-bearing migmatite from the Variscan orogen in northeastern Sardinia. The migmatite is associated with migmatised orthogneiss and Al-silicate-bearing pelitic migmatites. The protolith of the amphibole-bearing migmatite was a mid-Ordovician igneous rock of intermediate composition characterised by a biotite + plagioclase + quartz assemblage. The migmatite consists of mesosomes and tonalitic (or, less frequently, granodioritic) leucosomes, characterised by amphibole crystals (potassian ferropargasite) up to 2 cm in size. The tonalitic leucosomes are made up of quartz, pl…
Basaltic Rocks Analyzed by the Spirit Rover in Gusev Crater
2004
The Spirit landing site in Gusev Crater on Mars contains dark, fine-grained, vesicular rocks interpreted as lavas. Pancam and MiniâThermal Emission Spectrometer (Mini-TES) spectra suggest that all of these rocks are similar but have variable coatings and dust mantles. Magnified images of brushed and abraded rock surfaces show alteration rinds and veins. Rock interiors contain â¤25% megacrysts. Chemical analyses of rocks by the Alpha Particle X-ray Spectrometer are consistent with picritic basalts, containing normative olivine, pyroxenes, plagioclase, and accessory FeTi oxides. MoÌssbauer, Pancam, and Mini-TES spectra confirm the presence of olivine, magnetite, and probably pyroxene. The…
Is this Physical Education?: the motor commitment in Elementary Education
2019
[Resumen] La Educación Física ha de promover el desarrollo de hábitos de vida saludables y la prevención de enfermedades como la obesidad infantil. Para ello es necesario conocer el tiempo que el alumnado está en movimiento realizando actividad física en nuestras clases. Por lo tanto, el presente estudio tiene como objetivo analizar el tiempo de compromiso motor (TCM) en las sesiones de Educación Física (EF) en la etapa de Educación Primaria (EP). La muestra estuvo formada por 38 participantes de 1º y 5º curso. En total, se registraron nueve sesiones de EF impartidas por un único maestro especialista mediante una hoja de registro elaborada ad hoc. Los resultados muestran bajos valores de TC…
Migrating neuroblasts of the rostral migratory stream are putative targets for the action of nitric oxide
2007
It has been demonstrated that the gaseous messenger nitric oxide influences cell proliferation and cell migration, and therefore affects adult neurogenesis in mammals. Here, we investigated the putative targets for this action in the rostral migratory stream of the rat. We used immunocytochemical detection of the beta1 subunit of the enzyme soluble guanylyl cyclase, which can be activated by nitric oxide. Our results under light and electron microscopy demonstrated that the migrating neuroblasts (type A cells) were beta1-immunopositive. The astrocytes (type B cells), immature precursors (type C cells) and ependymal cells (type E cells) were beta1-immunonegative. The neurochemical characteri…
A constitutively active pituitary adenylate cyclase activating polypeptide (PACAP) type I receptor shows enhanced photoaffinity labeling of its highl…
2001
Abstract In the present study, we have analyzed a previously identified constitutively active pituitary adenylate cyclase activating polypeptide (PACAP) type I (PAC1) receptor with a deletion of the single amino acid residue Glu 261 (Y.-J. Cao, G. Gimpl, F. Fahrenholz, A mutation of second intracellular loop of pituitary adenylate cyclase activating polypeptide type I receptor confers constitutive receptor activation, FEBS Lett. 469 (2000)). This glutamic acid residue is highly conserved within the second intracellular loop of class II G protein-coupled receptors and may thus be of importance for many members of this receptor class. To explore the molecular characteristics of this mutant re…
Phase equilibria modelling of kyanite-bearing anatectic paragneisses from the central Grenville Province
2008
Kyanite-bearing paragneisses from the Manicouagan Imbricate Zone and its footwall (high-P belt of the central Grenville Province) preserve evidence of partial melting with development of metamorphic textures involving biotite-garnet ± kyanite ± plagioclase ± K-feldspar-quartz. Garnet in these rocks displays a variety of zoning patterns with respect to Ca. Pseudosection modelling in the Na O-CaO-K O-FeO-MgO-Al O - SiO -H O-TiO -O (NCKFMASHTO) system using measured bulk rock compositions accounts for the textural evolution of two aluminous and two sub-aluminous samples from the presumed thermal peak to conditions at which retained melt solidified. The prograde features are best explained by p…
Oxidative stress tolerance, adenylate cyclase, and autophagy are key players in the chronological life span of Saccharomyces cerevisiae during winema…
2012
Most grape juice fermentation takes place when yeast cells are in a nondividing state called the stationary phase. Under such circumstances, we aimed to identify the genetic determinants controlling longevity, known as the chronological life span. We identified commercial strains with both short (EC1118) and long (CSM) life spans in laboratory growth medium and compared them under diverse conditions. Strain CSM shows better tolerance to stresses, including oxidative stress, in the stationary phase. This is reflected during winemaking, when this strain has an increased maximum life span. Compared to EC1118, CSM overexpresses a mitochondrial rhodanese gene-like gene, RDL2, whose deletion lead…
Incidencia de la beca salario: impacto, perfil y rendimiento de los estudiantes
2013
En España, dentro del marco de la Estrategia 2015, la implantación de las becas de estudio, y especialmente las becas salario adaptadas a la nueva situación del Espacio Europeo de Educación Superior, pretenden garantizar el acceso a los estudios universitarios a aquellos grupos sociales más desfavorecidos económicamente. La presente investigación realiza un estudio ex post facto, de carácter descriptivo-comparativo dirigido a valorar la incidencia de la beca salario, como factor económico, sobre la equidad, el acceso y sobre el rendimiento académico en el primer año de universidad. El estudio se ha realizado con un total de 10.394 estudiantes de nuevo acceso de la cohorte 2010-11 de la Univ…
La acción social católica en Valencia y la educación del proletariado (1891-1917)
1980
Analizar el movimiento social y católico y su incidencia en el movimiento obrero en el campo de la educación. Movimiento social católico. Análisis de la situación histórica-social de España. Análisis del nuevo ideario religioso a partir de la encíclica Rerum Novarum. Praxis del catolicismo social en Valencia centrada en: actividades docentes, círculos católicos, patronatos de la juventud obrera, escuelas populares católicas, etc., y extensión cultural. Documentos de archivo. Prensa local. Bibliografía. Análisis histórico-descriptivo-analítico. El catolicismo social no permaneció al margen de su época y emprendió la búsqueda de la regeneración del obrero. Su solución era la regeneración pers…