Search results for "Classification"
showing 10 items of 29475 documents
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives
2014
A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…
Improving statistical classification methods and ecological status assessment for river macroinvertebrates
2016
Aquatic ecosystems are facing a growing number of human-induced stressors and the need to implement more biomonitoring to assess the ecological status of water bodies is eminent. This dissertation aims at providing tools to reduce the costs and improve the accuracy of freshwater benthic macroinvertebrate biomonitoring. To improve the cost-e ciency, we consider automated classi cation and develop a novel classi er suitable for complex macroinvertebrate image data. To enhance the accuracy of macroinvertebrate biomonitoring, we study the statistical properties of the Percent Model A nity index crucial to current Finnish biomonitoring and the factors a ecting these statistics. Finally, we perfo…
Calcium mediated polyelectrolyte adsorption on like-charged surfaces.
2011
International audience; Monte Carlo simulations within the primitive model of calcium-mediated adsorption of linear and comb polyelectrolytes onto like-charged surfaces are described, focusing on the effect of calcium and polyion concentrations as well as on the ion pairing between polymers and calcium ions. We use a combination of Monte Carlo simulations and experimental data from titration and calcium binding to quantify the ion pairing. The polymer adsorption is shown to occur as a result of surface overcharging by Ca2+ and ion pairing between charged monomers and Ca2+. In agreement with experimental observations, the simulations predict that the polymer adsorption isotherm goes through …
Predicting Individual Differences from Brain Responses to Music using Functional Network Centrality
2022
Individual differences are known to modulate brain responses to music. Recent neuroscience research suggests that each individual has unique and fundamentally stable functional brain connections irrespective of the task they perform. 77 participants’ functional Magnetic Resonance Imaging (fMRI) responses were measured while continuously listening to music. Using a graph-theory-based approach, we modeled whole-brain functional connectivity. We then calculate voxel-wise eigenvector centrality and subsequently use it to classify gender and musical expertise using binary Support Vector Machine (SVM). We achieved a cross-validated classification accuracy of 97% and 96% for gender and musical exp…
The link of a finitely determined map germ from R 2 to R 2
2010
Let f: (R2, 0) → (R2, 0) be a finitely determined map germ. The link of f is obtained by taking a small enough representative f: U ⊂ R2 → R2 and the intersection of its image with a small enough sphere Sε1 centered at the origin in R2. We will describe the topology of f in terms of the Gauss word associated to its link.
Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Rel…
2020
This research aimed to evaluate the effects of the inclusion of honey bee pollen (HBP) in meagre (Argyrosoumus regius) juveniles&rsquo
Evolutionary advantage conferred by an eukaryote-to-eukaryote gene transfer event in wine yeasts
2015
Although an increasing number of horizontal gene transfers have been reported in eukaryotes, experimental evidence for their adaptive value is lacking. Here, we report the recent transfer of a 158-kb genomic region between Torulaspora microellipsoides and Saccharomyces cerevisiae wine yeasts or closely related strains. This genomic region has undergone several rearrangements in S. cerevisiae strains, including gene loss and gene conversion between two tandemly duplicated FOT genes encoding oligopeptide transporters. We show that FOT genes confer a strong competitive advantage during grape must fermentation by increasing the number and diversity of oligopeptides that yeast can utilize as a s…
Aeolian Remobilisation of the 2011-Cordón Caulle Tephra-Fallout Deposit: Example of an Important Process in the Life Cycle of Volcanic Ash
2020
Although volcanic eruptions represent short periods in the whole history of a volcano, the large amount of loose pyroclastic material produced, combined with aeolian processes, can lead to continuous, long-lasting reworking of volcanic products. Driven by wind, these processes significantly influence the geomorphology and prolong the impacts of eruptions on exposed communities and ecosystems. Since such phenomena are of interest to scientists from a range of disciplines (e.g., volcanology, atmospheric and soil sciences), a well-defined, common nomenclature is necessary to optimise the multidisciplinary characterisation of both processes and deposits. We, therefore, first describe ash wind-r…
Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy
2015
ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.
Helminth Infection of the Loggerhead Sea Turtle Caretta caretta along the Coasts of Sicily and the North West Adriatic Sea
2021
We provide new data on the presence of helminth parasites in 64 individual loggerhead sea turtles Caretta caretta stranded along the coasts of Sicily and the northwest Adriatic Sea between June 2014 and August 2016. The necropsy examination revealed 31 individuals (48.4%) positive for endoparasites, showing a greater prevalence of trematodes than nematodes. In particular, seven species and a single genus of Trematoda (Hapalotrema) and a single species and genus of Nematoda (Kathlania) were identified. Among the Digenea flukes the species with the highest prevalence of infection were Rhytidodes gelatinosus (34.6%) and Hapalotrema sp. (33.3%), while among the Nematoda they were Kathlania sp. …