Search results for "Clero"

Chlamydia trachomatis Infection and Anti-Hsp60 Immunity: The Two Sides of the Coin

2009

Chlamydia trachomatis (CT) infection is one of the most common causes of reproductive tract diseases and infertility. CT-Hsp60 is synthesized during infection and is released in the bloodstream. As a consequence, immune cells will produce anti-CT-Hsp60 antibodies. Hsp60, a ubiquitous and evolutionarily conserved chaperonin, is normally sequestered inside the cell, particularly into mitochondria. However, upon cell stress, as well as during carcinogenesis, the chaperonin becomes exposed on the cell surface (sf-Hsp60) and/or is secreted from cells into the extracellular space and circulation. Reports in the literature on circulating Hsp and anti-Hsp antibodies are in many cases short on detai…

The Role of Perceived Energy and Self-Beliefs for Physical Activity and Sports Activity of Patients With Multiple Sclerosis and Chronic Stroke

2021

Physical activity counteracts some of the negative consequences associated with chronic neurological diseases. Here, we describe the levels of physical activity (PA) and sports activity (Sport) in patients with multiple sclerosis (pMS, n = 59) and chronic stroke (pStroke, n = 67) and test compliance with the recommendation for health-promoting physical activity of the World-Health Organization (WHO). Secondly, we tested for differences between the groups of patients, and thirdly, we examined relationships between PA and Sport with psychological indicators of perceived energy (fatigue and vitality) and self-beliefs (self-efficacy and self-control). Psychological constructs were assessed with…

Lichen sclerosus as a cause of recurrent cystitis: case report and review of the literatury.

2012

Lipofilling and platelet rich plasma, Hyaluronic acid and platelet rich plasma: new perspectives for scleroderma patients

2016

Should we routinely measure low-density and high-density lipoprotein subclasses?

2009

Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) plasma populations are composed of heterogeneous subfractions that are different in size, density and protein/lipid content. There is increasing evidence that small, dense LDL particles are strongly associated with higher cardiovascular disease risk. Similarly, several studies have investigated whether smaller HDL particles are more protective than their larger counterparts and more recent findings suggest that small, dense HDL has significantly higher atheroprotective activity than larger L HDL. Yet, certain impairments of the protein/lipid content in small, dense HDL may decrease its antiatherogenic capacity or even induce p…

Estudio piloto del tratamiento del liquen escleroso vulvar mediante tejido adiposo asociado a plasma rico en plaquetas autólogos

2020

Estudio piloto del tratamiento del liquen escleroso vulvar mediante tejido adiposo asociado a plasma rico en plaquetas autólogo. 1. Introducción. El Liquen escleroso (LE) es una enfermedad inflamatoria crónica, mediada por Linfocitos T (LT), de etiología desconocida que afecta fundamentalmente a la piel genital. Aunque La etiología exacta del LE es desconocida, se considera una enfermedad de origen multifactorial y cada vez se aboga más por el mecanismo autoinmune basado en su asociación con otras enfermedades de este tipo (Tiroiditis Hashimoto, alopecia Areata, vitíligo y anemia perniciosa) hasta en un 21-28% de los casos. La prevalencia en la población general se estima en 1 de cada 300-1…

A novel beneficial effect of liraglutide: the reduction in subclinical atherosclerosis in patients with type-2 diabetes.

2012

Galectin-3 and Lp(a) plasma concentrations and advanced carotid atherosclerotic plaques: Correlation with plaque presence and features

2019

Introduction: atherosclerosis is one of the leading causes of death and morbidity worldwide. It consists in the development of plaques in the intima media layers of arteries due to lipid accumulation and oxidation, causing massive inflammation. We aim to better understand the role of Galectin-3 (Gal-3) and Lipoprotein(a) [Lp(a)] as possible peripheral markers of plaque presence. Methods: Gal-3 and Lp(a) were measured in plasma samples from 99 patients undergoing carotid endarterectomy and 78 healthy controls, by immunometric assays. Plaques were classified histologically, according to the American Heart Association (AHA) guidelines as type Va (fibroatheroma), Vb (mainly calcific) and Vl (co…

Differences in intercellular communication during clinical relapse and gadolinium-enhanced MRI in patients with relapsing remitting multiple sclerosi…

2018

This study was designed based on the hypothesis that changes in both the levels and surface marker expression of extracellular vesicles (EVs) isolated from the cerebrospinal fluid (CSF) may be associated with the clinical form, disease activity, and severity of multiple sclerosis (MS). The analyzes were performed on subjects affected by MS or other neurological disorders. EVs, which were isolated by ultracentrifugation of CSF samples, were characterized by flow cytometry. A panel of fluorescent antibodies was used to identify the EV origin: CD4, CCR3, CCR5, CD19, and CD200, as well as isolectin IB4. The Mann–Whitney U-test and Kruskal–Wallis test were used for statistical analyzes. EVs isol…

Magnetic Resonance Venography of chronic cerebrospinal venous insufficiency in patients with associated multiple sclerosis

2011

Background: Multiple sclerosis (MS) is a chronic disease with not well understood etiology. Recently, a possible association of MS with compromised venous outflow from the brain and spinal cord has been studied (chronic cerebrospinal venous insufficiency – CCSVI). Angioplasties of internal jugular veins (IJV) and azygous vein (AV) have given promising results, with improvements in patients’ clinical status. Material/Methods: 830 patients with clinically defined MS were scanned from the level of sigmoid sinuses to the junction with brachiocephalic veins, as well as at the level of AV. T2-weighted, 2D TOF and FIESTA sequences were used. Results: The examination revealed a slower blood flow in…