Search results for "Clinical evidence"

showing 6 items of 16 documents

The laparoscopic approach to Acute Mesenteric Ischemia is today unclear and less debated (AMI). There are in fact no clinical evidences on this parti…

2016

The laparoscopic approach to Acute Mesenteric Ischemia is today unclear and less debated (AMI). There are in fact no clinical evidences on this particular focus and only few articles can be found in several databases (pubmed, cochrane library, etc.), and the problem concerns both diagnostic and therapeutic utilization of the procedure. These considerations were already taken into account in 2012 EAES guidelines where the Grade of Recommendation (GoR) of laparoscopy in AMI was low in both diagnostic and therapeutic aspects. According to the new Oxford Classification [1], the use of laparoscopy in patients with suspicious or diagnosed AMI presents a weak GoR.

The laparoscopic approach to Acute Mesenteric Ischemia is today unclear and less debated (AMI). There are in fact no clinical evidences on this particular focus and only few articles can be found in several databases (pubmed cochrane library etc.) and the problem concerns both diagnostic and therapeutic utilization of the procedure. These considerations were already taken into account in 2012 EAES guidelines where the Grade of Recommendation (GoR) of laparoscopy in AMI was low in both diagnostic and therapeutic aspects. According to the new Oxford Classification [1] the use of laparoscopy in patients with suspicious or diagnosed AMI presents a weak GoR.
researchProduct

Management of metabolic adverse events of targeted therapies and immune checkpoint inhibitors in cancer patients: an Associazione Italiana Oncologia …

2020

The growing insights in the next-generation immunotherapy and the state-of-the-art advancement in targeted-agents significantly improved clinical outcome of cancer patients by pointing towards a unexplored Achilles' heel. Novel toxicity profiles have been uncovered, representing unmet medical needs. Thus, a panel of expert provide comprehensive pharmacological and clinical evidence, to provide a patient-tailored approach to metabolic adverse events associated with novel anti-cancer treatments. Prompted by the need of a multidisciplinary cooperation, a working group of Associazione Italiana Oncologia Medica (AIOM), Associazione Medici Diabetologi (AMD) and Societa Italiana Farmacologia (SIF)…

diabetes; dyslipidemia; hypercholesterolemia; hyperglycemia; hypertriglyceridemia; immunotherapy; metabolic effect; targeted therapy; Consensus; Humans; Immunologic Factors; Italy; Medical Oncology; Neoplasms; Physicians0301 basic medicinemedicine.medical_specialtyConsensusSettore MED/06 - Oncologia MedicaImmune checkpoint inhibitorsmedicine.medical_treatmentPatient riskhypertriglyceridemiaMedical OncologyTargeted therapy03 medical and health sciences0302 clinical medicineMultidisciplinary approachNeoplasmsPhysiciansmedicineHumansImmunologic FactorsIntensive care medicineAdverse effectdiabeteshypercholesterolemiabusiness.industrydyslipidemiametabolic effectHematologytargeted therapy030104 developmental biologyOncologyItalyClinical evidence030220 oncology & carcinogenesisMetabolic effectsPosition paperhyperglycemiaimmunotherapybusiness
researchProduct

Exercise effects on cardiovascular disease: from basic aspects to clinical evidence.

2021

Contains fulltext : 283453.pdf (Publisher’s version ) (Closed access) Cardiovascular (CV) disease (CVD) remains the leading cause of major morbidity and CVD- and all-cause mortality in most of the world. It is now clear that regular physical activity (PA) and exercise training (ET) induces a wide range of direct and indirect physiologic adaptations and pleiotropic benefits for human general and CV health. Generally, higher levels of PA, ET, and cardiorespiratory fitness (CRF) are correlated with reduced risk of CVD, including myocardial infarction, CVD-related death, and all-cause mortality. Although exact details regarding the ideal doses of ET, including resistance and, especially, aerobi…

education.field_of_studymedicine.medical_specialtyPhysiologybusiness.industryPopulationVascular damage Radboud Institute for Health Sciences [Radboudumc 16]Cardiorespiratory fitnessDiseasemedicine.diseaseCardiorespiratory FitnessEndurance trainingClinical evidenceCardiovascular DiseasesRisk FactorsPhysiology (medical)medicineHumansMyocardial infarctionCardiology and Cardiovascular MedicineeducationPhysiologic AdaptationsAdverse effectIntensive care medicinebusinessExerciseCardiovascular Research
researchProduct

Application of palliative ventilation: potential and clinical evidence in palliative care.

2017

medicine.medical_specialtyPalliative carebusiness.industryNursing researchPain medicineMEDLINElaw.invention03 medical and health sciences0302 clinical medicine030228 respiratory systemOncologylawClinical evidenceVentilation (architecture)medicine030212 general & internal medicineIntensive care medicinebusinessSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
researchProduct

Nutrition and dry eye: a systematic review

2019

Objective: To identify the clinical evidence in the literature about the relationship between nutrition or dietary supplements and dry eye syndrome.Methods: A systematic review was performed after ...

medicine.medical_specialtygenetic structuresbusiness.industryBiomedical Engineering03 medical and health sciencesOphthalmology0302 clinical medicineClinical evidence030221 ophthalmology & optometrymedicineIntensive care medicinebusiness030217 neurology & neurosurgeryOptometryExpert Review of Ophthalmology
researchProduct

Recent clinical evidence on metronomic dosing in controlled clinical trials: a systematic literature review.

2020

Introduction: Metronomic dosing is used to give continuous chemotherapy at low doses. The low doses have minimal side effects and may enable cancer treatment to be remodeled toward the management o...

medicine.medical_specialtymedicine.medical_treatmentAntineoplastic Agents030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineClinical Trials Phase II as TopicNeoplasmsAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansRadiology Nuclear Medicine and imagingDosingIntensive care medicineRandomized Controlled Trials as TopicChemotherapybusiness.industryLow doseHematologyGeneral MedicineProgression-Free SurvivalCancer treatmentClinical trialSurvival RateSystematic reviewOncologyClinical Trials Phase III as TopicClinical evidence030220 oncology & carcinogenesisAdministration MetronomicbusinessActa oncologica (Stockholm, Sweden)
researchProduct