Search results for "Clinical variables"

showing 10 items of 19 documents

Body Mass Index and Associated Clinical Variables in Patients with Non-Celiac Wheat Sensitivity.

2019

Background: Non-Celiac Wheat Sensitivity (NCWS) is still a largely undefined condition, due to the lack of a diagnostic marker. Few data are available about the nutritional characteristics of NCWS patients at diagnosis. Aims: To evaluate the proportion of NCWS patients who were underweight, normal weight, overweight, or obese at diagnosis, and to search for possible correlations between their Body Mass Index (BMI) and other NCWS-related disease characteristics. Patients and Methods: The clinical charts of 145 NCWS patients (125 F, 20 M, mean age 37.1 &plusmn

0301 basic medicineAdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaClinical variablesHLA haplotypelcsh:TX341-641autoimmune diseaseAutoimmunityDiseaseWheat HypersensitivityOverweightBody Mass Index (BMI)GastroenterologyArticleBody Mass IndexCeliac Disease (CD)03 medical and health sciencesIrritable Bowel Syndrome (IBS)0302 clinical medicineThinnessWeight lossInternal medicineHLA-DQ AntigensmedicineHumansIn patientautoimmune diseasesIrritable bowel syndromeRetrospective StudiesNutrition and Dieteticsbusiness.industrynutritional and metabolic diseasesMiddle AgedOverweightmedicine.diseasePrognosis030104 developmental biologyHaplotypesnon-celiac wheat sensitivity (NCWS)030211 gastroenterology & hepatologyFemalemedicine.symptomUnderweightbusinesslcsh:Nutrition. Foods and food supplyBody mass indexFood ScienceNutrients
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The carriers of the A/G-G/G allelic combination of the c.2039 A>G and c.-29 G>A FSH receptor polymorphisms retrieve the highest number of oocytes in …

2016

The objective of this study was the elucidation of the possible role of the single-nucleotide polymorphisms (SNP) at position -29 and 2039 of the FSH receptor gene (FSHR) as independent predictive markers of ovarian response. Indeed, the tailoring of reproductive treatments is crucial for both maximizing the success of IVF patients and obtaining a reduction in hypo- or hyper-response rates. This prospective, observational study analyzed the association of -29 and 2039 FSHR polymorphisms with the number of retrieved oocytes in 140 patients attending an IVF/ICSI cycle for severe male factors (≤5,000,000 spermatozoa/mL) or tubal factors at the ANDROS Day Surgery Clinic, Palermo, Italy. The res…

0301 basic medicineAdultmedicine.medical_specialtyClinical variablesAdolescentGenotypePregnancy RateOocyte RetrievalFertilization in VitroBiology03 medical and health sciences0302 clinical medicineOvulation InductionPregnancyInternal medicineCOHmedicineGeneticsSNPHumansSperm Injections IntracytoplasmicAlleleGenetics (clinical)AllelesTreatment personalization030219 obstetrics & reproductive medicineIVF/ICSISurgery clinicObstetrics and GynecologyGeneral MedicineIvf icsiHuman genetics030104 developmental biologyEndocrinologyReproductive MedicineFSH receptor polymorphismOocytesReceptors FSHFemaleFsh receptor geneFollicle-stimulating hormone receptorDevelopmental Biology
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Is proteomics of value in cardiovascular risk assessment?

2019

Purpose of review To briefly summarize recently published evidence in the field of cardiovascular proteomics, focusing on its ability to improve cardiovascular risk stratification and critically discussing still open and burning issues and future perspectives of proteomics research. Recent findings Several epidemiological studies have demonstrated an improvement in cardiovascular risk prediction beyond traditional risk factors by adding novel biomarkers, identified by both discovery and targeted proteomics. However, only a moderate improvement in risk discrimination over clinical variables was observed. Moreover, despite different outcomes there was also a strong overlap of identified candi…

0301 basic medicineProteomicsClinical variablesGrowth Differentiation Factor 15Endocrinology Diabetes and MetabolismDisease030204 cardiovascular system & hematologyProteomicsBioinformaticsRisk Assessment03 medical and health sciences0302 clinical medicineRisk FactorsGeneticsMedicineAnimalsHumansBiomarker discoveryNatriuretic PeptidesMolecular BiologyNutrition and Dieteticsbusiness.industryInterleukinsCell BiologyTargeted proteomics030104 developmental biologyC-Reactive ProteinCardiovascular DiseasesRisk stratificationMetalloproteasesCardiology and Cardiovascular MedicinebusinessRisk assessmentBiomarkersCurrent opinion in lipidology
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Bone loss around narrow implants versus standard diameter implants: Retrospective 2-years case-control study

2019

Background The objectives were to evaluate the bone loss (BL) around narrow diameter implants (3.3 mm) 2 years after implant loading and compare with the bone loss around conventional-diameter implants (4.1 mm), as well as with clinical and anatomical variables. 2-years follow-up. Material and Methods Cases: 20 patients either gender-age, narrow implants (Straumann TM-SLA, diameter 3.3 mm); Control: 20 patients matching for gender-age, conventional implants (Straumann TM-SLA, diameter 4.1). Total 82 implants (31 narrow implants and 51 conventional implants) in 40 patients. To avoid statistical bias, a cluster of one implant per patient was randomly selected (20 narrow implants and 20 conven…

0303 health sciencesProsthetic DentistryTobacco useClinical variablesPost hocbusiness.industryRadiographyResearchDentistry030206 dentistry:CIENCIAS MÉDICAS [UNESCO]03 medical and health sciences0302 clinical medicineStatistical significanceUNESCO::CIENCIAS MÉDICASMedicineImplantImplant loadingbusinessGeneral Dentistry030304 developmental biologyJournal of Clinical and Experimental Dentistry
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Latency of interictal epileptiform discharges in long-term EEG recordings in epilepsy patients.

2015

AbstractPurposeTo assess the latency of interictal epileptiform discharges (IED) and seizures in long-term EEG recordings of patients with epilepsy.MethodIED latency was measured in 210 consecutive patients (mean (SD) age 38.6±13.9 years) with active epilepsy and the relationship to clinical variables was analyzed retrospectively. Median duration of EEG recording was 101.5h (95% confidence interval [CI] 92 to 117h).ResultsIEDs were absent in 45 (21.4%) and present in 165 (78.6%) patients who had a longer duration (p<0.001) and early onset (p<0.01) of epilepsy and more often had IEDs in prior standard EEGs (p<0.01), a structural etiology (OR 2.4, CI: 2.1–2.7), or temporal lobe epilepsy (OR 9…

AdultMaleClinical variablesTime FactorsClinical NeurologyVideo RecordingElectroencephalographyEeg recordingEpilepsySeizuresMedicineHumansIctalLatency (engineering)Negative studiesRetrospective StudiesLong-term EEGEpilepsymedicine.diagnostic_testbusiness.industryBrainElectroencephalographyGeneral MedicineInterictal epileptiform dischargesmedicine.diseaseConfidence intervalNeurologyAnesthesiaLatencyAnticonvulsantsFemaleNeurology (clinical)businessSeizure
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The eye-tracking computer device for communication in amyotrophic lateral sclerosis

2013

Objective To explore the effectiveness of communication and the variables affecting the eye-tracking computer system (ETCS) utilization in patients with late-stage amyotrophic lateral sclerosis (ALS). Methods We performed a telephone survey on 30 patients with advanced non-demented ALS that were provisioned an ECTS device. Median age at interview was 55 years (IQR = 48–62), with a relatively high education (13 years, IQR = 8–13). A one-off interview was made and answers were later provided with the help of the caregiver. The interview included items about demographic and clinical variables affecting the daily ETCS utilization. Results The median time of ETCS device possession was 15 months …

AdultMalemedicine.medical_specialtyClinical variablesEye MovementsCommunication Aids for DisabledPhysical medicine and rehabilitationmedicineHumansIn patientAmyotrophic lateral sclerosisComputer devicebusiness.industryData CollectionAmyotrophic Lateral SclerosisEye movementHigh educationGeneral MedicineMiddle Agedmedicine.diseaseCaregiversNeurologyMedian timeBrain-Computer InterfacesCommunication DisordersPhysical therapyEye trackingFemaleNeurology (clinical)businessActa Neurologica Scandinavica
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Visual memory dysfunction as a neurocognitive endophenotype in bipolar disorder patients and their unaffected relatives. Evidence from a 5-year follo…

2019

BACKGROUND: Scarce research has focused on Visual Memory (VM) deficits as a possible neurocognitive endophenotype of bipolar disorder (BD). The main aim of this longitudinal, family study with healthy controls was to explore whether VM dysfunction represents a neurocognitive endophenotype of BD. METHODS: Assessment of VM by Rey-Osterrieth Complex Figure Test (ROCF) was carried out on a sample of 317 subjects, including 140 patients with BD, 60 unaffected first-degree relatives (BD-Rel), and 117 genetically-unrelated healthy controls (HC), on three occasions over a 5-year period (T1, T2, and T3). BD-Rel group scores were analyzed only at T1 and T2. RESULTS: Performance of BD patients was sig…

AdultMalemedicine.medical_specialtyLongitudinal study5 year follow upClinical variablesBipolar DisorderAdolescentEndophenotypesHealth StatusDiseaseAudiologyNeuropsychological TestsFamily Study03 medical and health sciencesYoung Adult0302 clinical medicineCognitionVisual memoryMedicineLongitudinal StudyHumansBipolar disorderLongitudinal StudiesNeurocognitionAgedMemory Disordersbusiness.industryMiddle Agedmedicine.diseaseFamily study030227 psychiatryVisual MemoryPsychiatry and Mental healthClinical PsychologyEndophenotypeEndophenotypeFemaleLongitudinal studyVisual memorybusinessNeurocognitive030217 neurology & neurosurgeryFollow-Up Studies
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Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome

2015

Objective To determine the direct and indirect effects of function on clinical variables such as age, pain intensity, years of the disease, severity of symptoms, and depression in women with electrodiagnostic and clinical diagnosis of carpal tunnel syndrome (CTS). Design A cross-sectional study. Setting Patients from an urban hospital referred to a university clinic. Methods Two hundred and forty-four (n = 224) women with CTS were included. Demographic and clinical data, duration of symptoms, function, symptom's severity of the symptoms, pain intensity, and depression were self-reported collected. Correlation and path analysis with maximum likelihood estimation were conducted to assess the …

Adultmedicine.medical_specialtyClinical variablesMaximum likelihoodPainDiseaseComorbiditySensitivity and SpecificitySeverity of Illness IndexRisk FactorsPrevalenceMedicineHumansCarpal tunnel syndromeAgedPain MeasurementHand functionbusiness.industryDepressionDirect effectsReproducibility of ResultsGeneral MedicineRecovery of FunctionMiddle Agedmedicine.diseaseCarpal Tunnel SyndromeCausalityAnesthesiology and Pain MedicineCross-Sectional StudiesPsicobiologiaSpainClinical diagnosisPhysical therapyNeuralgiaWomen's HealthFemaleNeurology (clinical)Self ReportSymptom AssessmentbusinessUrban hospital
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Risk factors associated with adverse events in neonates with peripherally inserted central catheter

2019

Abstract Background Peripherally inserted central catheters have become a priority in infants who require long-term intravenous therapy, but their use involves certain risks. Objective The aim of the study was to describe the occurrence of adverse events in newborns with peripherally inserted central catheters and to determine the risk factors associated with them. Methods A descriptive cross-sectional study was designed and performed. All neonates with peripherally inserted central catheters from October 1st, 2014 to September 30th, 2015 were included. The adverse events and sociodemographic and clinical variables related to neonates and analysed catheters were recorded. Results A total of…

Clinical variablesbusiness.industrymedicine.medical_treatmentPeripherally inserted central catheterExtravasation03 medical and health sciencesLow birth weight0302 clinical medicineIntravenous therapy030225 pediatricsAnesthesiamedicine030212 general & internal medicinemedicine.symptombusinessAdverse effectEnfermería Intensiva (English ed.)
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Socio-clinical variables affecting the level of self-care in elderly patients with heart failure

2019

Background: Promoting self-care is the cornerstone of heart failure management. The number of hospitalizations and unscheduled visits could be reduced in elderly patients with heart failure by the patients’ active involvement in self-care. Aims: The aim of this study was to measure the level of self-care in elderly patients with heart failure, to examine the influence of socio-clinical variables on the level of self-care, and identify the socio-clinical variables that are predictors of self-care. Methods: The study included 100 heart failure patients (48 female, 52 male) aged between 60 and 88 years, treated at the Oleśno Health Care Center (Poland). The European Heart Failure Self-care Beh…

MaleGerontologyClinical variableselderly patientsself-careHumansMedicineAgedAged 80 and overHeart FailureAdvanced and Specialized NursingThesaurus (information retrieval)Mini–Mental State Examinationmedicine.diagnostic_testbusiness.industryCornerstoneMiddle Agedmedicine.diseaseSelf CareMedical–Surgical NursingSocioeconomic FactorsPatient SatisfactionHeart failureEuropean Heart Failure Self-care Behavior Scale-9Self careMini-Mental State ExaminationFemalePolandCardiology and Cardiovascular MedicinebusinessEuropean Journal of Cardiovascular Nursing
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