Search results for "Cluster"

Multidimensional Clustering and Registration of Seismic Waveform Data

2011

‘I don’t know the answer to that question’: a corpus-assisted discourse analysis of White House Press Briefings

2013

White House Press Briefings, daily meetings with the press held by the White House Press Secretary, are the main information conduit for the White House (Kumar 2007). They are considered a “political chess game” where the Press Secretary and the press face a “wrestling match” (Partington 2006: 16). Our analysis is carried out on a corpus comprising all the Press Briefings across three presidencies from Clinton to Obama. The additional mark-up includes information about individual speakers and their role, allowing us to compare different discourse strategies adopted by the participants in the briefings at different points in time. This leads us to determine the extent of the differences in t…

High resolution mouse subventricular zone stem cell niche transcriptome reveals features of lineage, anatomy, and aging

2020

AbstractAdult neural stem cells (NSC) serve as a reservoir for brain plasticity and origin for certain gliomas. Lineage tracing and genomic approaches have portrayed complex underlying heterogeneity within the major anatomical location for NSC, the subventricular zone (SVZ). To gain a comprehensive profile of NSC heterogeneity, we utilized a well validated stem/progenitor specific reporter transgene in concert with single cell RNA sequencing to achieve unbiased analysis of SVZ cells from infancy to advanced age. The magnitude and high specificity of the resulting transcriptional data sets allow precise identification of the varied cell types embedded in the SVZ including specialized parench…

Theoretical study of the molecular structure and the stability of neutral and reduced tetracyanoethylene

2003

Abstract The molecular structure and the stability of neutral, anionic, and dianionic tetracyanoethylene (TCNE) have been studied with MP2, coupled-cluster (CC), and density functional theory (DFT) procedures. The optimized geometries are in agreement with the available experimental data, although significant deviations for the CN bond distance have been obtained at the MP2 level. The adiabatic electron affinity of TCNE calculated with the B3LYP method is overestimated by 0.32 eV. In the light of the CC results, the source of such an overestimation is suggested to lie on the theoretical approach, rather than on a too low experimental value.

Determinants of between-hospital variations in outcomes for patients admitted with COPD exacerbations: findings from a nationwide clinical audit (AUD…

2015

Background Previous studies have demonstrated significant variability in the processes of care and outcomes of chronic obstructive pulmonary disease (COPD) exacerbations. The AUDIPOC is a Spanish nationwide clinical audit that identified large between-hospital variations in care and clinical outcomes. Here, we test the hypothesis that these variations can be attributed to either patient characteristics, hospital characteristics and/or the so-called hospital-clustering effect, which indicates that patients with similar characteristics may experience different processes of care and outcomes depending on the hospital to which they are admitted. Methods A clinical audit of 5178 COPD patients co…

Protein Corona: Prevention of Dominant IgG Adsorption on Nanocarriers in IgG‐Enriched Blood Plasma by Clusterin Precoating (Adv. Sci. 10/2019)

2019

The development of nanocarriers for drug delivery is challenged by individual blood composition fluctuations. In article number 1802199, Svenja Morsbach and co‐workers report the accumulation of immunoglobulins in the protein corona of nanocarriers in IgG‐enriched blood plasma resulting in increased cell uptake. This could be prevented by pre‐coating the nanocarriers with the “stealth” protein clusterin. Cover design by Stefan Schuhmacher.

Melatonin and phytomelatonin: Chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—an overview

2021

Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of several physiological processes in both animals and plants. In the last century, it was reported that this molecule may be produced in high concentrations by several species belonging to the plant kingdom and stored in specialized tissues. In this review, the main information related to the chemistry of melatonin and its metabolism has been summarized. Furthermore, the biosynthetic pathway characteristics of animal and plant cells have been compared, and the main differences between the two systems highlighted. Additionally, in order to investigate the distribution of this indolamine in the plan…

Heterogeneous photo-assisted catalytic hydration/dehydration reactions based on Keggin and Wells-Dawson type heteropolytungstates

2021

Polyoxometalates (POMs) are a wide class of metal-oxygen clusters that can be applied in acid and oxidation catalysis, medicine, electrochemistry, materials design, or models for self-assembling nanoscale systems as long as green and cheap photocatalysts. Heteropolyacids (HPAs) are a POM subclass extensively used as homogeneous photocatalysts for the oxidation of organic substrates. Dispersing HPAs onto solid supports with a high surface area increases their specific surface area and hence (photo)catalytic activity. This chapter reports the use of selected HPAs, heteropolytungstates, immobilized on different supports as heterogeneous photocatalysts.

Certain doping concentrations caused half-metallic graphene

2017

This work is supported by National Natural Science Foundation of China (Grant No. 21173096).

Approximate treatment of higher excitations in coupled-cluster theory.

2005

The possibilities for the approximate treatment of higher excitations in coupled-cluster (CC) theory are discussed. Potential routes for the generalization of corresponding approximations to lower-level CC methods are analyzed for higher excitations. A general string-based algorithm is presented for the evaluation of the special contractions appearing in the equations specific to those approximate CC models. It is demonstrated that several iterative and noniterative approximations to higher excitations can be efficiently implemented with the aid of our algorithm and that the coding effort is mostly reduced to the generation of the corresponding formulas. The performance of the proposed and …