Search results for "Cnidaria"
showing 4 items of 74 documents
Histone Deacetylase Inhibitors
2020
Histone deacetylases (HDACs) are key components of the epigenetic machinery controlling gene expression. They are involved in chromatin remodeling events via post-translational histone modifications but may also act on nonhistone proteins, influencing many fundamental cellular processes. Due to the key involvement of HDACs in serious human pathologies, including cancer, HDAC inhibitors (HDACis) have received increased attention in recent years. It is known that marine invertebrates produce significant amounts of secondary metabolites showing active pharmacological properties and an extensive spectrum of biomedical applications. Some of these compounds possess HDACi properties.
First record of conulariids from the Tērvete Formation, Upper Devonian of Latvia
2020
Phosphatized remains belonging to conulariids have been found in the Middle Famennian (Upper Devonian) deposits of the TÄrvete Formation of Latvia for the first time. The ornamentation pattern and characteristics of the exoskeleton indicate that the conulariids, represented by two incomplete and flattened specimens, belong to a single species within the genus Paraconularia. Paraconularia sp. from the TÄrvete Formation differs from Conularia latviensis Delle from the JoniÅ¡kis Formation in size and details of the morphology of the periderm; however, most probably, the species C. latviensis also belongs to the genus Paraconularia. Finding well-preserved almost complete conulariids agrees with…
Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates
2020
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety of diseases. The aim of this review is to pick up selected studies that report the extraction and identification of crude extracts or isolated compounds that exert a modulatory effect on collective cell locomotion and/or skin tissue reconstitution and recapitulate the molecular, biochemical, and/or physiological aspects, where available, which are associated to the substances und…
Data from: The joint evolution of the Myxozoa and their alternate hosts: a cnidarian recipe for success and vast biodiversity
2018
The relationships between parasites and their hosts are intimate, dynamic and complex; the evolution of one is inevitably linked to the other. Despite multiple origins of parasitism in the Cnidaria, only parasites belonging to the Myxozoa are characterized by a complex life cycle, alternating between fish and invertebrate hosts, as well as by exceptionally high species diversity. This inspired us to examine the history of reciprocal interactions and adaptive radiations in myxozoans and their hosts by determining the degree of congruence between their phylogenies and by timing the emergence of myxozoan lineages in relation to their hosts. Recent genomic analyses suggested a common origin of …