Search results for "CoDi"
showing 10 items of 1391 documents
Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes
2019
Background Type 1 diabetes mellitus (T1DM) patients display increased risk of cardiovascular disease (CVD) and are characterized by a diminished regulatory T (Treg) cell content or function. Previous studies have shown an association between decreased CDKN2A/2B/2BAS gene expression and enhanced CVD. In the present study the potential relationship between CDKN2A/2B/2BAS gene expression, immune cell dysfunction and increased cardiovascular risk in T1DM patients was explored. Methods A cross-sectional study was performed in 90 subjects divided into controls and T1DM patients. Circulating leukocyte subpopulations analysis by flow cytometry, expression studies on peripheral blood mononuclear cel…
¿Viva la corrupción?
2005
Barcoding of parasitoid wasps (Braconidae and Chalcidoidea) associated with wild and cultivated olives in the Western Cape of South Africa 1
2019
Wild and cultivated olives harbor and share a diversity of insects, some of which are considered agricultural pests, such as the olive fruit fly. The assemblage of olive-associated parasitoids and seed wasps is rich and specialized in sub-Saharan Africa, with native species possibly coevolving with their hosts. Although historical entomological surveys reported on the diversity of olive wasp species in the Western Cape Province of South Africa, no comprehensive study has been performed in the region in the molecular era. In this study, a dual approach combining morphological and DNA-based methods was used for the identification of adult specimens reared from olive fruits. Four species of Br…
Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer.
2013
Recently, the ectopic expression of myoglobin (MB) was reported in human epithelial cancer cell lines and breast tumor tissues, where MB expression increased with hypoxia. The better prognosis of MB-positive breast cancer patients suggested that the globin exerts a tumor-suppressive role, possibly by impairing mitochondrial activity in hypoxic breast carcinoma cells. To better understand MB gene regulation in cancer, we systematically investigated the architecture of the human MB gene, its transcripts and promoters. In silico analysis of transcriptome data from normal human tissues and cancer cell lines, followed by RACE-PCR verification, revealed seven novel exons in the MB gene region, mo…
Combinatorial Transforms : Application in Lossless Image Compression
2011
International audience; Common image compression standards are usually based on frequency transform such as Discrete Cosine Transform. We present a different approach for lossless image compression, which is based on a combinatorial transform. The main transform is Burrows Wheeler Transform (BWT) which tends to reorder symbols according to their following context. It becomes one of promising compression approach based on context modeling. BWT was initially applied for text compression software such as BZIP2 nevertheless it has been recently applied to the image compression field. Compression schemes based on the Burrows Wheeler Transform have been usually lossless; therefore we implement th…
El Petroleo o la vida
2002
Comparative analysis of variation and selection in the HCV genome
2016
AbstractGenotype 1 of the hepatitis C virus (HCV) is the most prevalent of the variants of this virus. Its two main subtypes, HCV-1a and HCV-1b, are associated to differences in epidemic features and risk groups, despite sharing similar features in most biological properties. We have analyzed the impact of positive selection on the evolution of these variants using complete genome coding regions, and compared the levels of genetic variability and the distribution of positively selected sites. We have also compared the distributions of positively selected and conserved sites considering different factors such as RNA secondary structure, the presence of different epitopes (antibody, CD4 and C…
Esperienze sfavorevoli infantili e dipendenza da sostanze: contesti di vita e narrazioni nella CECA interview
2014
Introduzione: La letteratura internazionale sul ruolo delle esperienze infantili nella strutturazione della personalità adulta riconosce l’impatto a lungo termine di situazioni traumatiche precoci (Bifulco, Moran, 1998; Fonagy et al, 2002; Giannone et al, 2011). Le diverse tipologie di abuso (emotivo, fisico e sessuale) vissute nella prima infanzia possono aumentare lo strutturarsi in età adulta di problemi legati al consumo di sostanze stupefacenti e condizioni di dipendenza (Dube et al., 2003; Huang et al, 2011; Lansford et al., 2010; Pederson et al, 2008). Risulta pertanto importante l’approfondimento delle condizioni di sviluppo che sottostanno allo strutturarsi di tali patologie. La Ch…