Search results for "CoV"

showing 10 items of 9749 documents

Active recovery shows favorable IGF-I and IGF binding protein responses following heavy resistance exercise compared to passive recovery

2019

IGF-I and IGFBPs have important physiological modulatory effects and this study sought to examine the influence of active vs. passive recovery following a heavy resistance exercise on IGF-I and IGF binding protein (IGFBP) recovery responses. It was hypothesized that increased IGF-I and decreased inhibitory IGFBPs during active recovery may be reflective of cascades promoting physiological recovery. 18 untrained men ((AR n = 7, PR n = 11), age: 26 ± 4 years, height: 174 ± 8 cm, body mass: 75 ± 13 kg) performed either a protocol-specific 10 × 10 × 30% 1RM active (AR) or passive recovery (PR) session following a heavy resistance exercise session performed on a leg press device (10 × 10 1RM). M…

AdultMale0301 basic medicinemedicine.medical_specialtyEndocrinology Diabetes and MetabolismPassive recovery030209 endocrinology & metabolismIsometric exercise03 medical and health sciences0302 clinical medicineEndocrinologyInternal medicinemedicineHumansInsulin-Like Growth Factor ILeg pressMorningbusiness.industryBinding proteinResistance trainingResistance TrainingRecovery of FunctionInsulin-Like Growth Factor Binding Proteins030104 developmental biologyEndocrinologyFemalebusinessGrowth Hormone & IGF Research
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Analysis of Renal and Cardiac Outcomes in Male Participants in the Fabry Outcome Survey Starting Agalsidase Alfa Enzyme Replacement Therapy Before an…

2020

Rossella Parini,1,2 Guillem Pintos-Morell,3 Julia B Hennermann,4 Ting-Rong Hsu,5 Nesrin Karabul,6 Vasiliki Kalampoki,7 Andrey Gurevich,7 Uma Ramaswami8 On behalf of the FOS Study Group1Rare Metabolic Diseases Unit, MBBM Foundation, San Gerardo Hospital, Reference Centre for Hereditary Metabolic Disorders (MetabERN), Monza, Italy; 2TIGET Institute, IRCCS San Raffaele Hospital, Milan, Italy; 3Division of Rare Diseases, Reference Centre for Hereditary Metabolic Disorders (MetabERN), University Hospital Vall d’Hebron, Autonomous University of Barcelona, Barcelona, Spain; 4Villa Metabolica, Department of Pediatric and Adolescent Medicine, University Medical Center, Mainz, Germany; 5Dep…

AdultMale0301 basic medicinemedicine.medical_specialtyestimated glomerular filtration rateAdolescentPharmaceutical ScienceRenal functionLeft ventricular hypertrophyFabry Outcome SurveyYoung Adult03 medical and health sciences0302 clinical medicineInternal medicineDrug DiscoverymedicineHumansEnzyme Replacement TherapyEstimated glomerular filtration rateChildAgalsidase alfaOriginal ResearchRetrospective StudiesPharmacologyagalsidase alfaFabry diseaseProteinuriaDrug Design Development and Therapybusiness.industryLeft ventricular hypertrophyEnzyme replacement therapyMiddle Agedmedicine.diseaseFabry diseaseRecombinant Proteinsleft ventricular hypertrophyIsoenzymesTreatment Outcome030104 developmental biologyMale patientalpha-Galactosidase030220 oncology & carcinogenesisEnzyme replacement therapyCohortmedicine.symptombusinessAgalsidase alfa
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Vaccination coverage in healthcare workers: a multicenter cross-sectional study in Italy

2019

Introduction In recent years, a phenomenon known as "vaccine hesitancy" has spread throughout the world, even among health workers, determining a reduction in vaccination coverage (VC). A study aimed at evaluating VC among healthcare workers (HCWs) in 10 Italian cities (L'Aquila, Genoa, Milan, Palermo, Sassari, Catanzaro, Ferrara, Catania, Naples, Messina) was performed. Materials and methods Annex 3 of the Presidential Decree n. 445 of 28 December 2000 was used to collect information on the vaccination status of HCWs. The mean and standard deviation (SD) were calculated with regard to the quantitative variable (age), while absolute and relative frequencies were obtained for categorical dat…

AdultMale0303 health sciencesVaccines030306 microbiologyHealth PersonneleducationNursesMiddle AgedInfectious Disease Transmission Professional-to-PatientNO03 medical and health sciencesHealthcare workers; Vaccination coverage; VaccinesCross-Sectional StudiesHealthcare workers Vaccination coverage VaccinesItalyPhysiciansHealthcare workerHumansHealthcare workersOriginal ArticleFemaleVaccination coverage
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Levels and variables associated with psychological distress during confinement due to the coronavirus pandemic in a community sample of Spanish adults

2020

Due to the COVID-19 pandemic's consequences and the state of alarm, literature has shown that people worldwide have experienced severe stressors that have been associated with increased prevalence of emotional distress. In this study, we explored psychological distress (depression, anxiety, and somatization symptoms) using an online survey platform in a sample of 1,781 Spanish adults during the confinement due to COVID-19, relationships between distress and sleep problems, affect, pain, sleep, emotional regulation, gender, type of housing, history of psychopathology, and living alone during the confinement, and differences depending on demographic and psychological variables. Results showed…

AdultMale050103 clinical psychologyAdolescentPhysical DistancingPopulationAffect (psychology)Cognitive reappraisalYoung Adult03 medical and health sciences0302 clinical medicinemedicineHumans0501 psychology and cognitive sciencesSomatoform DisorderseducationPandemicsAgedAged 80 and overDepressive Disordereducation.field_of_studySARS-CoV-205 social sciencesEmocionsCOVID-19LonelinessMiddle Agedmedicine.diseaseAnxiety Disorders030227 psychiatryAnsietatClinical PsychologyDistressSpainQuarantineAnxietyFemalemedicine.symptomPsychologySomatizationStress PsychologicalPsychopathologyClinical psychologyClinical Psychology & Psychotherapy
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Emotional and Behavioral Consequences of the COVID-19 Pandemic: The Role of Health Anxiety, Intolerance of Uncertainty, and Distress (In)Tolerance.

2020

The COVID-19 pandemic represents a worldwide threat to mental health. To optimize the allocation of health care resources, research on specific vulnerability factors, such as health anxiety, intolerance of uncertainty, and distress (in)tolerance, and particularly their effect on the time course of SARS-CoV-2 related anxiety appears crucial for supporting high risk groups suffering from elevated mental distress during the pandemic. N = 887 participants (78.4% female

AdultMale050103 clinical psychologysafety behaviorsCoronavirus disease 2019 (COVID-19)Health Toxicology and MutagenesisPneumonia Virallcsh:Medicinevirus anxietyAnxietyPsychological DistressArticle03 medical and health sciencesMental distress0302 clinical medicineGermanyPandemicHealth careSafety behaviorsintolerance of uncertaintyMedicineHumans0501 psychology and cognitive sciencesPandemicsbusiness.industry05 social scienceslcsh:RPublic Health Environmental and Occupational HealthUncertaintyCOVID-19Middle AgedMental healthDistresshealth anxietyAnxietyFemaledistress tolerancemedicine.symptombusinessCoronavirus InfectionsAttitude to Health030217 neurology & neurosurgeryClinical psychologyInternational journal of environmental research and public health
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Epidemiological, clinical and genomic snapshot of the first 100 B.1.1.7 SARS-CoV-2 cases in Madrid

2021

A new SARS-CoV-2 variant, B.1.1.7, emerged in September in the UK, and is responsible for 76.6% of COVID-19 cases.1 This variant has also been reported in another 45 countries, 17 of them European.2,3 B.1.1.7 is considered to have higher transmissibility.4 It carries an unusually high number of specific mutations/deletions, 18, mostly non-synonymous and eight concentrate in the S gene,5 including several which might have relevant functional roles. The 69/70 deletion may be associated to immune response evasion6 and the N501Y substitution increases the affinity to the ACE2 receptor.7 These findings have raised the alarm of having to face a new variant with the potential to accelerate the spr…

AdultMale2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)AdolescentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)030231 tropical medicine03 medical and health sciencesYoung Adult0302 clinical medicineResearch LetterMedicineHumans030212 general & internal medicineUKChildB.1.1.7travelAgedAged 80 and overTravelbusiness.industrySARS-CoV-2InfantCOVID-19General MedicineGenomicsMiddle AgedSpainChild PreschoolFemalebusinessHumanitiesAcademicSubjects/MED00295
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Type I interferons as the potential mechanism linking mRNA COVID-19 vaccines to Bell's palsy

2021

Therapies - Sous presse. Epreuves corrigees par l'auteur. Disponible en ligne depuis le mardi 13 avril 2021

AdultMale2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)COVID-19 vaccines030226 pharmacology & pharmacyArticle03 medical and health sciencesPharmacovigilance0302 clinical medicineBell's palsyPhase 3 clinical trialsBell PalsymedicineType I interferonsHumansBell's palsyPharmacology (medical)Potential mechanismComputingMilieux_MISCELLANEOUSAgedCOVID-19 coronavirus disease 2019Vaccines SyntheticMessenger RNASARS-CoV-2business.industryCOVID-19Bell’s palsyMiddle Agedmedicine.diseaseVirologymRNA messenger RNA3. Good healthInterferon Type IFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusiness
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Changes in Alcohol Consumption Pattern Based on Gender during COVID-19 Confinement in Spain

2021

(1) The goal of this study was to analyze the prevalence and pattern of alcohol consumption (frequency of consumption, average daily consumption, and risky consumption) before and during confinement due to the coronavirus disease (COVID-19) in the adult population and based on gender. (2) Methods: Data from 3779 individuals were collected via a set of online surveys. The AUDIT alcohol consumption questions (AUDIT-C) were used to measure the frequency of consumption, the average daily consumption, intensive consumption, risky consumption, and standard drink units. (3) Results: During confinement, the prevalence of alcohol consumption declined in both males and females, but only intensive con…

AdultMale2019-20 coronavirus outbreakmedicine.medical_specialty6114.06 Comportamiento del ConsumidorCoronavirus disease 2019 (COVID-19)Alcohol DrinkingHealth Toxicology and Mutagenesis3309.01 Bebidas Alcohólicasrisk consumptionHealth BehaviorAdult populationFrequency of use030508 substance abusestandard drink unit (SDU)Article03 medical and health sciences0302 clinical medicine6302.02 Psicología SocialSurveys and QuestionnairesgenderMedicineHumans030212 general & internal medicineConsumption (economics)business.industryalcoholSARS-CoV-2Public healthPublic Health Environmental and Occupational HealthRCOVID-19confinement measures63 SociologíaStandard drinkSpainMedicineFemale0305 other medical sciencebusinessAlcohol consumptionDemographyInternational Journal of Environmental Research and Public Health
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Incidence of severe COVID-19 outcomes in psoriatic patients treated with systemic therapies during the pandemic: A Biobadaderm cohort analysis

2021

AdultMale2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)prospective cohortMEDLINEDermatologyregistryimmunosuppressive agentsSeverity of Illness IndexCOVID-19 (Malaltia)ArticleCohort StudiesInternal medicinePandemicPsoriasisHumansMedicinebiologic therapyRegistriesAgedbusiness.industryIncidenceIncidence (epidemiology)COVID-19COVID-19 Psoriasis biologic therapy immunosuppressive agents pharmacovigilance prospective cohort registryMiddle AgedSpainpharmacovigilanceFemalebusinessPsoriasi -- TractamentCohort studyJournal of the American Academy of Dermatology
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Long-term functional and psychological recovery in a population of acute respiratory distress syndrome patients treated with VV-ECMO and in their car…

2019

Background Acute respiratory distress syndrome (ARDS) survivors are affected with long-term physical/mental impairments, with improvements limited mostly to the first year after intensive care (ICU) discharge. Furthermore, caregivers of ICU patients exhibit psychological problems after family-member recovery. We evaluated the long-term physical and mental recovery of ARDS survivors treated with veno-venous extracorporeal membrane oxygenation (VV-ECMO), and the long-term psychological impact on their caregivers. Methods Single-center prospective evaluation of a retrospective cohort of 75 ARDS patients treated with VV-ECMO during a seven-year period (25.10.2009-11.08.2016). Primary outcomes w…

AdultMaleARDSPediatricsmedicine.medical_specialtyPopulationAnxietyStress Disorders Post-Traumatic03 medical and health sciences0302 clinical medicineExtracorporeal Membrane OxygenationTracheostomyQuality of life030202 anesthesiologyIntensive careMedicineHumansSurvivorseducationDepression (differential diagnoses)Retrospective StudiesPatient health questionnaireeducation.field_of_studyPsychological TestsRespiratory Distress Syndromebusiness.industryDepression030208 emergency & critical care medicineRetrospective cohort studyRecovery of FunctionLength of StayMiddle Agedmedicine.diseasePatient Health QuestionnaireCritical careAnesthesiology and Pain MedicineTreatment OutcomeCaregiversQuality of LifeAnxietyFemalemedicine.symptombusinessFollow-Up StudiesMinerva anestesiologica
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