Search results for "Coccyx"

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Near-Haploidy in a Malignant Sacrococcygeal Teratoma

1999

Cytogenetic analysis of a malignant sacrococcygeal teratoma in an adult patient revealed near-haploid (77%), near-diploid (19%), and polyploid (4%) cells. The near-haploid cells had a karyotype of 25,XX,der(5)t(5;7)(p15;p13),+7,der(9)t(6;9)(p21;q34),r(17)(p13q25) . In the near-diploid and polyploid cells identical copies of the structural chromosomal changes were found. Although some of the anomalies observed appear unique to this case, a common breakpoint in chromosome 6 was previously reported as specific in a subgroup of extragonadal germ cell tumors of adults.

SacrumCancer Researchmedicine.medical_specialtyPathologyNear-HaploidyExtragonadalChromosomal translocationHaploidyBiologyTranslocation GeneticPolyploidyFatal OutcomeGeneticsmedicineHumansMolecular BiologyAgedCoccyxPloidiesSpinal NeoplasmsfungiTeratomaCytogeneticsChromosome MappingChromosomeKaryotypeAnatomymedicine.diseaseDiploidyKaryotypingChromosomes Human Pair 5Chromosomes Human Pair 6FemaleGerm cell tumorsChromosomes Human Pair 9Tomography X-Ray ComputedSacrococcygeal teratomaChromosomes Human Pair 7Cancer Genetics and Cytogenetics
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