Search results for "Cod"
showing 10 items of 2985 documents
Air Pollution: Role of Extracellular Vesicles-Derived Non-Coding RNAs in Environmental Stress Response
2023
Air pollution has increased over the years, causing a negative impact on society due to the many health-related problems it can contribute to. Although the type and extent of air pollutants are known, the molecular mechanisms underlying the induction of negative effects on the human body remain unclear. Emerging evidence suggests the crucial involvement of different molecular mediators in inflammation and oxidative stress in air pollution-induced disorders. Among these, non-coding RNAs (ncRNAs) carried by extracellular vesicles (EVs) may play an essential role in gene regulation of the cell stress response in pollutant-induced multiorgan disorders. This review highlights EV-transported ncRN…
Vertaileva analyysi live coding -sävellysympäristöihin
2010
Tässä tutkielmassa selvitetään mitä live coding on ja tutustutaan nel- jään live coding -sävellysympäristöön aloittelijan näkökulmasta. Ohjelmia vertail- laan neljän piirteen avulla ensisijaisesti käytettävyyden ja helpon omaksuttavuuden kannalta.
Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD
2021
Background and aim: Coffee intake exerts protective effects against non-alcoholic fatty liver disease (NAFLD), although without fully cleared mechanisms. In this study we aimed to assess whether coffee consumption may influence the expression of long non-coding RNAs (lncRNAs) in the liver. Methods: C57BL/6J mice were fed a 12-week standard diet (SD), high-fat diet (HFD) or HFD plus decaffeinated coffee solution (HFD + coffee). Expression of specific lncRNAs involved in NAFLD was analyzed by real-time PCR. For the most differentially expressed lncRNAs, the analysis was also extended to their mRNA targets. Results: Decaffeinated coffee intake reduced body weight gain, prevented NAFLD, lowered…
Licenziamento disciplinare e dirigenza degli enti locali, tra legge, contrattazione collettiva e codici di comportamento
2022
The essay analyzes the legal and contractual discipline of the disciplinary and managerial responsibilities of the management of local authorities, with particular reference to some clauses of the codes of conduct applicable to the staff of local autonomies.
Long non-coding RNAs during embryogenesis of the sea urchin
2014
Intriguing studies suggest that long non-coding RNAs (lncRNAs) tend to act in cis with neighboring protein-coding genes. Based on this notion, we assessed whether lncRNAs originate from adjacent genomic regions of selected protein-coding genes, such as early-H2A histone and strim1, that play important functions during development of the sea urchin Paracentrotus lividus. Downregulation of H2A expression relies on the sns5 chromatin insulator placed at the 3'-end of H2A. Northern blot hybridization show that a lncRNA (of ~600 nt), not overlapping with the H2A mRNA, is transcribed from sns5, following H2A expression. The strim1 locus encodes the first echinoderm TRIM-containing factor which fu…
Low-code izstrādes platformas: lietotņu tiesību pārvaldība
2022
Low-code tehnoloģija strauji kļūst populāra, 2025.gadā 70% no komerciāli veidotajām lietotnēm būs low-code.[1] Augot tehnoloģijas popularitātei ir svarīgi arī pievērst uzmanību, ka low-code lietotnēs ir pilnvērtīga drošība. Bakalaura darbā tiek aplūkots viens no drošības aspektiem - tiesību pārvaldība. Tiesības nodrošina piekļuves kontroli izstrādātajās lietotnēs. Darba ietvaros tiek izstrādātas low-code lietotnes, lai pārliecinātos, ka pilnvērtīgi var ieviest tiesību pārvaldību un piekļuves kontroli izveidotajās lietotnēs. Rezultātā tiek parādīts, ka šobrīd low-code izstrādes platformās ir iespējams realizēt pilnvērtīgas lietotnes, bet paliek atvērts jautājums, vai mērķauditorija, kura vei…
Investigating Novice Developers’ Code Commenting Trends Using Machine Learning Techniques
2023
Code comments are considered an efficient way to document the functionality of a particular block of code. Code commenting is a common practice among developers to explain the purpose of the code in order to improve code comprehension and readability. Researchers investigated the effect of code comments on software development tasks and demonstrated the use of comments in several ways, including maintenance, reusability, bug detection, etc. Given the importance of code comments, it becomes vital for novice developers to brush up on their code commenting skills. In this study, we initially investigated what types of comments novice students document in their source code and further categoriz…
Classifying economics for the common good : a note on the links between sustainable development goals and JEL codes
2021
Purpose This brief note sheds light on the links between Journal of Economic Literature (JEL) codes and the Sustainable Development Goals (SDGs) of the United Nations. Design/methodology/approach Three alternative methods based on keyword overlap to establish links between SDGs and JEL codes are presented. Findings These simple linkages illustrate that the themes of SDGs have corresponding closely related JEL classification codes. Research limitations/implications The mappings presented in this note are based on simple keyword overlap and are therefore necessarily imperfect and incomplete. There is plenty of room for further development. Practical implications Despite the demonstrated possi…
Molecular cloning and characterization of the complementary DNA coding for the B-chain of murine Clq
1989
AbstractcDNA clones coding for the B-chain of murine Clq were isolated from a mouse macrophage library. The characterized clones include the total coding region plus a leader sequence. High homology was found with human Clq B-chain in the coding region (81%). Northern blot analysis of total RNA from different tissues of Balb/c mice showed one band of approximately 1.2 kb. The highest signal was found in RNA preparations of thioglycolate-activated peritoneal macrophages. The probe also hybridized with mRNA from spleen, thymus and heart. Extremely weak signals were found in liver, kidney, lung and intestine tissues.