Search results for "Cod"
showing 10 items of 2985 documents
NEO1 and NEO-EXT studies: Long-term safety of repeat avalglucosidase alfa dosing for 4.5 years in late-onset Pompe disease patients
2019
Safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of repeat avalglucosidase alfa dosing (5, 10, or 20 mg/kg qow) for 6 months were evaluated in NEO1 (NCT01898364) in late-onset Pompe disease patients either treatment-naive (Naive) or having received alglucosidase alfa for ≥9 months (Switch). In NEO-EXT (NCT02032524), an ongoing NEO1 extension, long-term safety and pharmacokinetics of repeat avalglucosidase alfa dosing will be monitored over 6 years. Interim safety results after 4.5 years of NEO-EXT are reported here. Mean ages at NEO1 enrollment were: Naive: 44.8 (SD:20.3, range:20-78) years and Switch: 46.7 (SD:14.1, range:21-68) years. Of the 24 NEO1 parti…
Thinking Narratively. Between Novel-Essay and Narrative Essay
2022
What is the connection between philosophical enquiries and storytelling in contemporary narrative? Is it possible to outline some features of a so-called philosophical fiction in Western literature throughout the last two centuries? This book aims to provide a plural answer, hosting extensive essays by seven young researchers coming from different fields (Theory of literature, German, American, Russian and Italian contemporary literature, history and evolution of the essayistic form). A short The volume is addressed to all those with a strong interest in both evolution of philosophical speech and history of the novel and has a strong vocation to promote interdisciplinarity in literary studi…
"Janie do Cię wracamy w czarnoleskie lipy". Polskie tradycje źródłowe w odmianach literacko-kulturowej współczesności (wybory - powtórzenia - różnice)
2018
The subject of the article - developed through the literary and cultural contexts of contemporary literature - concentrates mainly on different forms of the presence of tradition (targeting the Romantic one as key and the Old Polish as the subsequent one). A look at the styles and tones of the literature-"thriving" languages of these traditions allows us to see these traditions in a different critical light (national symbols/Polish signs/patters/transformations).
Necesidad de tratamiento ortodóncico e impacto psicosocial de la estética dental en los adolescentes de la Comunidad Valenciana (2010)
2014
La Conferencia de Alma Ata sobre Atención Primaria de Salud en 1978 declaró que ''la salud es un estado de completo bienestar físico, mental y el bienestar social y no una mera ausencia de enfermedades o dolencias''. La maloclusión se ha asociado con problemas psicosociales derivados de una estética dentofacial deficiente, alteraciones funcionales en los casos más extremos (puede verse alterada el habla, la masticación y la articulación temporo-mandibular, entre otras) y una mayor susceptibilidad de desarrollar enfermedad periodontal, caries o sufrir traumatismos dentales; así, debe ser considerada como un problema de salud. La maloclusión no es una enfermedad en el sentido estricto por lo …
Oltre i testi unici verso la neocodificazione
2008
Il saggio, partendo dall''analisi delle ragioni sottese alla semplificazione normativa, mette in luce i profili evolutivi che conducono dai testi unici alla neocodificazione.
ENABLING LOCAL GOVERNMENTS TO DESIGN AND IMPLEMENT ANTI-CORRUPTION STRATEGIES THROUGH DYNAMIC PERFORMANCE MANAGEMENT AND GOVERNANCE. A CASE-STUDY OF …
2021
Lo scopo principale di questa ricerca è quello di inquadrare le possibili relazioni causali fra corruzione negli approvvigionamenti pubblici e performance delle amministrazioni locali. A tal fine, viene adottato un disegno di ricerca che integra dinamicamente metodi quantitativi e qualitativi in ogni fase del processo di studio. Gli approcci Dynamic Performance Management (DPM) e Governance (DPG), supportati da interviste approfondite non-strutturate, modellazioni formali e simulazioni quantitative, sono qui adottati per analizzare un caso di studio rappresentativo di un piccolo comune italiano in cui si sono verificati alcuni episodi di corruzione nelle attività di approvvigionamento nei p…