Search results for "Coffin"
showing 7 items of 7 documents
Coffins in Finland : the history of production, design and attitudes
2017
AbstractCoffins as death-related objects have changed in Finland during the past 150 years and the Finnish funeral industry has been created to answer the changing needs of customers. No longer do people build coffins in the household, or only buy a coffin and some other items from the funeral company: now professionals manage entire funerals. Coffin designs have become simpler and less socially discriminating and the colour formerly reserved for children and young people, white, has become the most popular colour for a coffin. Attitudes towards coffins have also changed, from mild dislike of having a coffin in the home to general demand of hiding coffins even in funeral companies’ premises…
Customised next-generation sequencing multigene panel to screen a large cohort of individuals with chromatin-related disorder
2020
BackgroundThe regulation of the chromatin state by epigenetic mechanisms plays a central role in gene expression, cell function, and maintenance of cell identity. Hereditary disorders of chromatin regulation are a group of conditions caused by abnormalities of the various components of the epigenetic machinery, namely writers, erasers, readers, and chromatin remodelers. Although neurological dysfunction is almost ubiquitous in these disorders, the constellation of additional features characterizing many of these genes and the emerging clinical overlap among them indicate the existence of a community of syndromes. The introduction of high-throughput next generation sequencing (NGS) methods f…
Death and Rebirth: Images of Death in Sicily
2015
Photographs were often taken during funerary ceremonies in Sicily. Local photographers were commissioned to document funerals as if they were christenings, communions or wedding ceremonies; and it is no mere coincidence that in funeral portraits the relatives arranged around the coffin assumed postures similar to those seen in photos of festivities. This tradition of taking photos during such “mixed occasions” gives the images a profound significance and highlights the archaic roots of the popular ideology of death as a continuum of life.
Localization of non-specific X-linked mental retardation gene (MRX73) to Xp22.2.
2001
Clinical and molecular studies are reported on a family (MRX73) of five males with non-specific X-linked mental retardation (XLMR). A total of 33 microsatellite and RFLP markers was typed. The gene for this XLMR condition was been linked to DXS1195, with a lod score of 2.36 at theta = 0. The haplotype and multipoint linkage analyses suggest localization of the MRX73 locus to an interval of 2 cM defined by markers DXS8019 and DXS365, in Xp22.2. This interval contains the gene of Coffin-Lowry syndrome (RSK2), where a missense mutation has been associated with a form of non-specific mental retardation. Therefore, a search for RSK2 mutations was performed in the MRX73 family, but no causal muta…
Intronic L1 insertion and F268S, novel mutations in RPS6KA3 (RSK2) causing Coffin-Lowry syndrome
2003
Two novel mutations of the ribosomal S6 kinase 2 gene (also known as RSK2) have been identified in two unrelated patients with Coffin–Lowry syndrome. The first mutation consists of a de novo insertion of a 5′-truncated LINE-1 element at position −8 of intron 3, which leads to a skipping of exon 4, leading to a shift of the reading frame and a premature stop codon. The L1 fragment (2800 bp) showed a rearrangement with a small deletion, a partial inversion of the ORF 2, flanked by short direct repeats which duplicate the acceptor splice site. However, cDNA analysis of the patient shows that both sites are apparently not functional. The second family showed the nucleotide change 803T>C in exon…
Alles für die Katz’?
2014
Summary The so-called cat’s coffin of prince Thutmose (Egyptian Museum Cairo, CG 5003), which was allegedly found during an excavation at Mit Rahina in 1892, is a curious monument. Whilst prince Thutmose is commonly regarded as a son of Amenhotep III, this coffin so far delivers the only known example for him as “eldest king’s son” and high priest of Ptah at Memphis. But, for several reasons, its authenticity seems to be very dubious.
An antique lead coffin discovered in Évreux (Eure): a multidisciplinary study
2013
The Roman cemetery of le Clos au Duc in Évreux (Eure) lasted from the 1st to the 4th c. AD. The most common funerary practice in the 1st c. AD was cremation. From the beginning of the 2nd c. AD this rapidly gave place to inhumation burials. By the end of the 3rd c. lead coffins could be found in burials, but it remained a minority practice reserved for an elite. The 2010 excavation in Évreux allowed the recovery of an example of these. It was incomplete, but the good preservation of its remains made a multidisciplinary study possible. Apart from the bones of a young woman, the lead coffin contained coins, textile, fur, calcite (CaCO3) and insects. These results make it possible to retrace t…