Search results for "Cohort Study"

showing 10 items of 3811 documents

Infective Endocarditis: Preliminary Results of a Cohort Study in the Southern Italian Population.

2020

Background Infective endocarditis (IE) is an uncommon disease with an involved interplay of clinical and surgical team management. We aimed to define diagnosis parameters and delineate in-hospital management in patients with IE admitted in a tertiary hospital of Southern Italian. Materials and methods Fifty-six consecutive patients (42 males, 14 females; age range: 34-85 years) admitted for IE in the Infectious Diseases, Cardiac Surgery, and Cardiology units, between January 2011 and August 2017, were enrolled. Demographic data, mortality, comorbidities, specimen type, microscopy results, special histological staining performed, and antimicrobial therapy were collected and analyzed. Any com…

microorganismmedicine.medical_specialtyArterial embolismcomplicationsCardiologyunivariate analysicandida endocarditi030204 cardiovascular system & hematologyendocarditi03 medical and health sciences0302 clinical medicinematlabInternal medicinemedicinegenderEndocarditisBlood cultureadult cardiac surgerymicroorganismsSurgical teamUnivariate analysismedicine.diagnostic_testbusiness.industryGeneral Engineeringmedicine.diseaseCardiac surgeryunivariate analysiscandida endocarditismultivariate analysisInfective endocarditismulti-drug resistant bacteriaendocarditisbusiness030217 neurology & neurosurgeryCohort studyCureus
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The early changes in trunk muscle strength and disability following lumbar spine fusion

2012

To analyze trunk muscle function pre- and postoperatively in patients undergoing lumbar spine fusion. Associations between changes in trunk muscle strength and disability were also studied.A total of 114 patients undergoing lumbar spine fusion participated in the study. The flexion and extension strength of the trunk was measured preoperatively and 3 months after surgery using a strain-gauge dynamometer. Disability and pain during the past week was evaluated with the Oswestry disability index (ODI) and visual analog scale (VAS), respectively.Preoperative trunk extension and flexion strength levels were 319 N and 436 N in males, respectively, and 160 N and 214 N in females, respectively. In …

musculoskeletal diseasesAdultMaleMuscle Strength Dynamometermedicine.medical_specialtyTime FactorsLumbar spine fusionVisual analogue scaleMuscle Strength DynamometerDisability EvaluationSurveys and QuestionnairesMedicineHumansDisabled PersonsMuscle StrengthProspective StudiesRange of Motion ArticularProspective cohort studyMuscle SkeletalAgedPain MeasurementPain PostoperativeLumbar Vertebraebusiness.industryRehabilitationTorsota3141Recovery of FunctionTorsoMiddle AgedTrunkSurgeryOswestry Disability Indexmedicine.anatomical_structureSpinal FusionTreatment OutcomeBack PainFemalebusinessRange of motionFollow-Up StudiesDisability and Rehabilitation
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Detection of bifid mandibular condyle using computed tomography

2011

Objective: To determine the frequency and characteristics of bifid mandibular condyle (BMC) using computed tomography (CT) evaluation. Study Design: A retrospective study was carried out using the CT records of 550 patients referred to the Medical School of Erciyes University (Kayseri, Turkey) between 2007 and 2010. T-tests were used to compare frequency of BMC between the left and right sides and between female and male patients. Statistical analysis was performed using SPSS software and a chi-squared test. Results: Of the 550 Patients, 10 patients (1.82%) were found to have BMCs. Five patients were female (50%) and five were male (50%). Of these 10 patients, 7 (70%) had unilateral and 3 (…

musculoskeletal diseasesAdultMaleTurkish populationAdolescentDentistryComputed tomographyOdontologíaCondyleYoung Adultstomatognathic systemmedicineHumansStatistical analysisChildGeneral DentistryAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologymedicine.diagnostic_testbusiness.industryMedical schoolMandibular CondyleRetrospective cohort studyMiddle Agedmusculoskeletal system:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludhumanitiesstomatognathic diseasesOtorhinolaryngologyMale patientUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleNuclear medicinebusinessTomography X-Ray ComputedBifid mandibular condyle
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Effectiveness of adalimumab for ulcerative colitis: A multicentre, retrospective study of clinical practice in Italy.

2022

Abstract Background Adalimumab is used to treat ulcerative colitis, but additional effectiveness and safety data are needed. Patients and methods This retrospective study considered adults with ulcerative colitis treated with adalimumab at 19 hospitals. Clinical data were collected from the start of treatment, after 2, 6 and 12 months, and at the last visit. Outcome measures of effectiveness were treatment duration, reasons for discontinuation and colectomy. Results We studied 381 patients treated with adalimumab for a median of 12.1 months. Disease activity at the start of treatment was moderate to severe in 262 cases (68.8%) and endoscopic activity was moderate to severe in 339 cases (89.…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentEffectivenessYoung AdultInternal medicineAdalimumabMedicineHumansAdverse effectskin and connective tissue diseasesColectomyColectomyAgedRetrospective StudiesReal-world evidenceHepatologybusiness.industryGastroenterologyEffectiveneAdalimumabRetrospective cohort studyInduction ChemotherapyMiddle Agedmedicine.diseaseUlcerative colitisDiscontinuationClinical PracticeTreatment OutcomeUlcerative colitisItalyAdalimumab; Effectiveness; Real-world evidence; Safety; Ulcerative colitisConcomitantColitis UlcerativeFemaleTumor Necrosis Factor InhibitorsSafetybusinessmedicine.drugDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Pain and clinical findings in the low back: a study of industrial employees with 5-, 10-, and 28-year follow-ups.

2009

Little is known about the relationships of clinical findings in the low back with low back pain (LBP) in the normal working population. We studied whether physiotherapist's findings in the low back were associated with local and radiating LBP among a cohort (n=902) of employees in the engineering industry. A systematic non-proportional sample was drawn in strata by age, gender, and occupational class. The non-proportionality aimed at increasing sample size in smaller strata. Physiotherapists performed the straight-leg raising test (SRL), and made assessments of the fingertip-to-floor distance and pain in palpation of the lumbar interspinous spaces. The variables on pain at the interspinous …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyLogistic regressionSeverity of Illness IndexPhysical medicine and rehabilitationhealth services administrationSeverity of illnessmedicineCluster AnalysisHumansGeneralizability theoryProspective StudiesProspective cohort studyWorkplaceReferred painbusiness.industryMiddle AgedLow back painHealth Surveysbody regionsAnesthesiology and Pain MedicineLogistic ModelsSample size determinationCohortPhysical therapypopulation characteristicsFemalemedicine.symptombusinessLow Back PainFollow-Up StudiesEuropean journal of pain (London, England)
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Rates of Upper Facet Joint Violation in Minimally Invasive Percutaneous and Open Instrumentation: A Comparative Cohort Study of Different Insertion T…

2017

Background Minimally invasive pedicle screw placement may have a higher incidence of violation of the superior cephalad unfused facet joint. Study Aims We investigated the incidence and risk factors of upper facet joint violation in percutaneous robot-assisted instrumentation versus percutaneous fluoroscopy-guided and open transpedicular instrumentation. Methods A retrospective study including all consecutive patients who underwent lumbar instrumentation, fusion, and decompression for spondylolisthetic stenosis and degenerative disk disease was conducted between January 2012 and January 2016. All operations were performed by the same surgeon; the patients were divided into three groups acc…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyPercutaneousDecompressionIntervertebral Disc DegenerationSurgical planningNeurosurgical ProceduresZygapophyseal JointFacet joint03 medical and health sciences0302 clinical medicineLumbarSpinal StenosisPedicle ScrewsRisk FactorsmedicineHumansInstrumentation (computer programming)AgedRetrospective Studies030222 orthopedicsLumbar Vertebraebusiness.industryRetrospective cohort studyMiddle Agedmusculoskeletal systemmedicine.diseaseSurgeryStenosismedicine.anatomical_structureSpinal FusionTreatment OutcomeSurgeryFemaleNeurology (clinical)business030217 neurology & neurosurgeryJournal of neurological surgery. Part A, Central European neurosurgery
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Monitoring bone growth using quantitative ultrasound in comparison with DXA and pQCT.

2008

Quantitative ultrasound (QUS) is a safe, inexpensive, and nonradiation method for bone density assessment. QUS correlates with, and predicts fragility fractures comparable to, dual-energy X-ray absorptiometry (DXA)-derived bone mineral density (BMD) in postmenopausal women. However, its validity in monitoring bone growth in children is not well understood. Two hundred and fifty-eight 10-13 yr pubertal girls and 9 37-43 yr adults without diseases or history of medications known to affect bone metabolism were included in the 2-yr prospective study. Calcaneal broadband ultrasound attenuation (cBUA) was assessed using QUS-2 (Quidel, Santa Clara, CA), speed of sound of tibial shaft (tSOS) using …

musculoskeletal diseasesAdultmedicine.medical_specialtyBone densityAdolescentEndocrinology Diabetes and MetabolismBone remodelingFractures BoneAbsorptiometry PhotonBone DensityMedicineHumansRadiology Nuclear Medicine and imagingOrthopedics and Sports MedicineProspective StudiesQuantitative computed tomographyProspective cohort studyChildFemoral neckUltrasonographyBone growthBone mineralmedicine.diagnostic_testbusiness.industryReproducibility of ResultsConcordance correlation coefficientmedicine.anatomical_structureFemaleRadiologybusinessNuclear medicineTomography X-Ray ComputedJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
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Möglichkeiten der CT-Arthrographie in der Diagnostik von Schulterinstabilitäten

1990

In the course of a prospective study, CT arthrography was carried out on 40 patients with shoulder instability. In 35 of these patients a lesion of the capsule and labrum was demonstrated, indicating glenohumeral instability; in three patients this was shown primarily by CT arthrography. In three patients, multidirectional instability was demonstrated. In four patients there was an isolated lesion of the labrum, whereas in one patient all the findings were normal. Compared with the capsulo-labral lesions, bone changes involving the head of the humerus and the glenoid were of lesser importance, although their severity affected the choice of operative treatment in four patients. Fifteen of th…

musculoskeletal diseasesLabrummedicine.medical_specialtybusiness.industryGlenohumeral instabilityCapsuleSurgeryLesionmedicine.anatomical_structuremedicineMultidirectional instabilityRadiology Nuclear Medicine and imagingHumerusCt arthrographymedicine.symptombusinessNuclear medicineProspective cohort studyRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Presence of Serum Antinuclear Antibodies Does Not Impact Long-Term Outcomes in Nonalcoholic Fatty Liver Disease

2020

Introduction We investigated the longitudinal impact of antinuclear antibody (ANA) on clinical outcomes and survival in nonalcoholic fatty liver disease (NAFLD). Methods ANA were found in 16.9% of 923 biopsy-proven NAFLD patients, but none of them had histologic autoimmune hepatitis (AIH) or developed AIH after a mean follow-up of 106±50 months. Results Although ANA-positive cases had a higher prevalence of nonalcoholic steatohepatitis at baseline, the occurrence of liver-related events, hepatocellula carcinoma, cardiovascular events, extrahepatic malignancy, and overall survival were similar to ANA-negative. Discussion Once AIH has been ruled out, the long-term outcomes and survival are un…

musculoskeletal diseasesMalemedicine.medical_specialtyAntibodies Antinuclear; Biopsy; England; Female; Humans; Italy; Longitudinal Studies; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Prevalence; Prospective Studies; Survival AnalysisAnti-nuclear antibodyBiopsySettore MED/12 - GASTROENTEROLOGIAAntibodies Antinuclear Biopsy EnglandFemale Humans Italy Longitudinal Studies Male Middle Aged Non-alcoholic Fatty Liver Disease Prevalence Prospective StudiesSurvival AnalysisAutoimmune hepatitisMalignancyGastroenterologyAntibodies03 medical and health sciences0302 clinical medicineimmune system diseasesNon-alcoholic Fatty Liver DiseaseInternal medicineAntinuclearBiopsyNonalcoholic fatty liver diseasemedicineCarcinomaPrevalenceHumansLongitudinal StudiesProspective Studiesskin and connective tissue diseasesProspective cohort studySurvival analysisHepatologymedicine.diagnostic_testbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseSurvival Analysisdigestive system diseases3. Good healthstomatognathic diseasesn/aEnglandItaly030220 oncology & carcinogenesisAntibodies Antinuclear030211 gastroenterology & hepatologyFemalebusiness
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Cemented and screw-retained implant-supported single-tooth restorations in the molar mandibular region: A retrospective comparison study after an obs…

2015

Objectives: The aim of this study was to evaluate the survival and compare the appearance of different mechanical and biological complications, in screw-retained and cemented-retained single-tooth implant-supported restorations localized in the molar mandibular region, over a period of 1 to 4 years. Material and Methods: A retrospective study was carried out with a total of eighty implant-supported restorations, which were placed in eighty patients for prosthetic rehabilitation of a mandibular molar. Forty patients were rehabilitated with a cemented-retained restoration and the other forty with a screw-retained restoration. The presence of the following complications was recorded for both t…

musculoskeletal diseasesMolarDentistryOdontologíaMucositisMedicineGeneral DentistryProsthetic DentistryImplantes dentalesbusiness.industryResearchMandibular regionSoft tissueRetrospective cohort studySingle tooth:CIENCIAS MÉDICAS [UNESCO]musculoskeletal systemequipment and suppliesmedicine.diseaseCiencias de la saludsurgical procedures operativeUNESCO::CIENCIAS MÉDICASComparison studybusinessComplication
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