Search results for "Cohort"

Eight new mutations and the expanding phenotype variability in muscular dystrophy caused by ANO5.

2012

Objective: Description of 8 new ANO5 mutations and significant expansion of the clinical phenotype spectrum associated with previously known and unknown mutations to improve diagnostic accuracy. Methods: DNA samples of 101 patients in 95 kindreds at our quaternary referral center in Finland, who had undetermined limb-girdle muscular dystrophy (LGMD), calf distal myopathy, or creatine kinase (CK) elevations of more than 2,000 IU/L, were selected for ANO5 genetic evaluation, and the clinical findings of patients with mutations were retrospectively analyzed. Results: A total of 25 patients with muscular dystrophy caused by 11 different recessive mutations in the ANO5 gene were identified. The …

Bébé compense-t-il la consommation d'un aliment plus ou moins énergétique juste avant le repas ? (ANR PUNCH)

2019

Débuter la diversification alimentaire : une décision influencée par la croissance de l'enfant ?

2019

National audience; Les pratiques d'alimentation des nourrissons sont soumises à des influences multiples. Ainsi, l'âge de début de diversification varie selon de nombreux facteurs comme les caractéristiques maternelles (tabagisme, âge, niveau d'études, corpulence, pays de naissance) ou infantiles (sexe) (Bournez et al., 2017). Nous voulions étudier si cet âge pouvait de plus dépendre de la croissance de l'enfant, et traduire ainsi une sensibilité de la mère à cet aspect du développement. Nous avons envisagé que les enfants les plus grands (ou lourds, ou corpulents) pourraient être diversifiés plus tôt que les enfants de taille « moyenne ». Les données de la cohorte ELFE (Etude Longitudinale…

Safety of hospital discharge before return of bowel function after elective colorectal surgery

2020

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

Exploring students’ identity development from the perspective of study difficulties

2020

This work-in-progress paper in research category reports preliminary findings on how students taking introductory computing courses develop identity from the perspective of study difficulties. The motivation was that students identified lack of meaning and prospects (cf. identity) as a study difficulty in a previous qualitative study. The present study further explores this finding by issuing both an identity development and a self-efficacy scale to a larger first-year student cohort. The aim is to characterize the study cohort by the aspects included in the identity development scale, and thereby increase understandings of students’ challenges. Moreover, a correlation analysis between iden…

Educational and family-related determinants of organized sports participation patterns from adolescence to emerging adulthood : A four-year follow-up…

2022

This study aimed to identify organized sports participation patterns and their prevalence from adolescence to emerging adulthood, and the educational and family-related determinants of the patterns. Adolescents in the Finnish Health Promoting Sports Club (FHPSC) study answered a health behaviour questionnaire and reported on sports club participation at ages 15 and 19 (N = 609). In emerging adulthood, dropouts (total 41.05%; females 43.72%; males 36.56%), maintainers (30.87; 26.44; 38.33), nonparticipants (27.59; 29.32; 24.67), and joiners (0.49; 0.52; 0.44) (p =.024) were identified. A mixed multinomial logistic regression analysis showed, that male gender, as compared to female gender, in…

Partnership formation and dissolution over the life course: applying sequence analysis and event history analysis in the study of recurrent events

2015

We present two types of approach to the analysis of recurrent events for discretely measured data, and show how these methods can complement each other when analysing co-residential partnership histories. Sequence analysis is a descriptive tool that gives an overall picture of the data and helps to find typical and atypical patterns in histories. Event history analysis is used to make conclusions about the effects of covariates on the timing and duration of the partnerships. As a substantive question, we studied how family background and childhood socio-emotional characteristics were related to later partnership formation and stability in a Finnish cohort born in 1959. We found that high se…

Predictors of long-term outcomes in patients undergoing periodontal maintenance

2017

Abstract Aim This retrospective study aimed to characterize the baseline status of patients following periodontal maintenance, analysing the association between the long‐term outcome of these patients, smoking, bruxism, and the main clinical and radiographic variables. Material and methods A sample of 174 patients with moderate to severe periodontitis was refined into homogeneous subsamples according to smoking and bruxism and the rate of tooth loss due to periodontal disease (TLPD): 0, 1–2, and >2 teeth. The association and the distribution (χ² test) of the variables within the subsamples were analysed. Results Smoking and bruxism were significantly associated with higher TLPD rates. Verti…

Bloodstream Infection Incidence of Different Central Venous Catheters in Neonates: A Descriptive Cohort Study

2017

Central venous catheters (CVCs) in neonates are associated with a risk of central line-associated bloodstream infections (CLABSI). Most reports on the incidence of CLABSI in neonates focus on umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs). We evaluated the incidence and risk factors for CLABSI in a cohort of neonates with femoral venous catheters (FVCs), UVCs, and PICCs, with a gestational age ≥34 weeks born between January 1, 2006 and June 30, 2013. We included 2,986 neonates with a total of 656 catheters. The CLABSI incidence rate varied from 12.3 per 1,000 catheter-days in FVCs to 10.6 per 1,000 catheter-days in UVCs and 5.3 per 1,000 catheter-days …

Appropriateness of requests for human serum albumin at the University Hospital of Palermo, Italy: a prospective study

2015

Abstract OBJECTIVE: First, to assess the appropriateness of requests for albumin using current guidelines; second, to evaluate physicians' compliance with this protocol. DESIGN: Descriptive, prospective study. SETTING: 'Paolo Giaccone' University Hospital in Palermo (Italy). PARTICIPANTS: The six departments with the highest orders for albumin. INTERVENTION: An experimental, pharmacist-driven process for daily orders of albumin was activated over a period of 1 month. Pharmacy personnel handed out order forms on six different wards. Physicians were required to select one of a number of intended uses listed on the form. MAIN OUTCOME MEASURES: Data on albumin and serum protein levels; number o…