Search results for "Colon"
showing 10 items of 2038 documents
Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme E…
2015
<b><i>Background:</i></b> Recently, we have shown anti-proliferative and pro-apoptotic effects of indicaxanthin associated with epigenetic modulation of the onco-suppressor <i>p16</i><sup><i>INK4a</i></sup> in the human colon cancer cell line CACO2. In the present study, the epigenetic activity of indicaxanthin and the mechanisms involved were further investigated in other colorectal cancer cell lines. <b><i>Methods:</i></b> LOVO1, CACO2, HT29, HCT116, and DLD1 cells were used to evaluate the potential influence of consistent dietary concentrations of indicaxanthin on DNA methylation, and the epigenetic mech…
Use of selected autochthonous lactic acid bacteria for Spanish-style table olive fermentation
2012
The present work presents a successful attempt to achieve an enhanced and more predictable fermentation process in Spanish-style green olive technology by selection and use of autochthonous starter cultures. During the first phase of this work, two Spanish-like fermentations of green table olives of cultivar (cv) “Nocellara del Belice”, coming from irrigated and not irrigated fields, were monitored, in order to highlight the best agricultural conditions for drupe production and to isolate lactic acid bacteria strains with relevant technological properties. Among 88 identified isolates, one Lactobacillus pentosus strain showed remarkable biochemical features and high acidification rate in sy…
Razzismi, discriminazioni e confinamenti
2013
"Rappresentazioni del corpo del colonizzato, riletture postcoloniali a confronto", Barbara Creed and Jeanette Hoorn (eds.), Body Trade, New York, Rou…
2003
Un'indagine interdisciplinare sulle raffigurazioni del corpo del colonizzato e del prigioniero, nel contesto del colonialismo europeo, in Australia e nel Pacifico, corre sul filo di questa raccolta di saggi, opera di autori di varie nazionalità e diversa formazione. I temi centrali di Body Trade, la mercificazione del corpo dell'Altro e le rappresentazioni del colonizzato, sono dibattuti con l'intento di riesaminare i miti della civiltà occidentale e del cannibalismo, attraverso l'analisi di un vasto repertorio di pratiche coloniali, prese a soggetto di romanzi, riviste, fotografie e film, tutte opere pubblicate lungo un arco temporale che si snoda dal Settecento ai giorni nostri.
Transverstites re-existences: A counterhistory from the visual difference in Peru
2018
El vínculo entre naturaleza y deshumanización es un discurso moderno colonial de género que mantiene su vigencia mediante la basurización simbólica y concreta de quienes son vistos como inferiores, antinaturales y hasta como animales, convertidos en un desecho de la sociedad. Una forma de visualizar al otro como elemento sobrante del sistema simbólico. En este sentido, maniobrar en el campo de la visualidad travesti, sus convenciones y estereotipos, se convierte en una práctica de resistencia en tanto que se enfrenta al régimen escópico eurocéntrico disciplinante, astutamente camuflado. Pero, igualmente, de re-existencia, al proponer la co-presencia visual de la diferencia, y por ende, la e…
Human leucocyte antigen-A2 restricted and Mycobacterium tuberculosis 19-kDa antigen-specific CD8+ T-cell responses are oligoclonal and exhibit a T-ce…
2001
CD8+ T cells can be grouped into two different types of secretory T lymphocytes, based on the cytokine-secretion pattern upon antigen exposure: those with a T-cell cytotoxic type 1 response (Tc1), which secrete interferon-gamma (IFN-gamma), or those with a T-cell cytotoxic type 2 response, which secrete interleukin (IL)-4 and IL-10. We examined the CD8+ T-cell response directed against an immunodominant human leucocyte antigen (HLA)-A2-presented peptide derived from a 19-kDa Mycobacterium tuberculosis-associated antigen. T cells were examined by functional analysis and by T-cell receptor (TCR) complementarity-determining region 3 (CDR3)-spectratyping, which defines the complexity of a T-cel…
Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B-restoration by exogenous interleuki…
2002
SUMMARYInsufficient stimulatory capacities of autologous dendritic cells (DC) may contribute in part to impaired T cell stimulation and therefore viral persistence in patients with chronic hepatitis B virus (HBV) infection. In order to characterize the antigen presenting functions of DC from chronic HBV carriers and controls antigen specific T cell responses were analysed. CD34+ peripheral blood progenitor cells were differentiated to immature DC in the presence of GM-CSF, IL-6/IL-6R fusion protein and stem cell factor. Proliferative CD4+ T cell responses and specific cytokine release were analysed in co-cultures of DC pulsed with HBV surface and core antigens or tetanus toxoid and autologo…
The polypyrimidine tract-binding protein (PTB) is involved in the post-transcriptional regulation of human inducible nitric oxide synthase expression.
2006
Human inducible nitric oxide synthase (iNOS) expression is regulated by transcriptional and post-transcriptional mechanisms. We have recently shown that the multifunctional RNA-binding proteins KH-type splicing regulatory protein and tristetraprolin are critically involved in the post-transcriptional regulation of human iNOS expression. Several reports have shown that KH-type splicing regulatory protein colocalizes with the polypyrimidine tract-binding protein (PTB), and both RNA-binding proteins seem to interact with the same mRNAs. Therefore we analyzed the involvement of PTB in human iNOS expression. In human DLD-1 cells, cytokine incubation necessary to induce iNOS expression did not ch…
Memorias silenciadas en la construcción de los servicios sociales
2006
Joaquin.Garcia-Roca@uv.es Este artículo revisa la historia de la formación del sistema público de servicios sociales en España y expone «las rutas que no se navegaron», los derechos y las aspiraciones a que dieron lugar o conformaron unas expectativas, el origen de la des institucionalización, la pérdida de movimiento social y el desarrollo comunitario. El principio neoliberal y la exaltación de la gestión, la conquista de las profesiones y la ingeniería social han contribuido a silenciar un proceso que todavía se puede recuperar. ¿Cómo? El autor plantea que los servicios sociales han de ser capaces de producir significados personales tales como el sentido de pertenencia, la confianza, la i…
AYLAN E COLONIA. DALLA GUERRA AI MIGRANTI AL RESPINGIMENTO DEI REFUGEES
2017
This contribution aims to shed light on the specific mechanism of migrant categorization implemented by the so-called «Hotspot approach», which was launched by the EU Agenda on Migration in May 2015. This approach is here envisaged as a response to the current changes in the composition of migration towards Europe. Provisions contained in EU and Italian policy documents are compared with concrete practices enacted on the ground by investigating two case studies: the initial opening of the Hotspot at Milo, in Trapani, and the first months of functioning of the Hotspot on Lampedusa. The empirical research covers the period between the last months of 2015 and the beginning of 2016. The short-t…